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Aliases for ADAMTSL4-AS1 Gene

Subcategory (RNA class) for ADAMTSL4-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for ADAMTSL4-AS1 Gene

  • ADAMTSL4 Antisense RNA 1 2 3 4 5
  • C1orf138 3 4
  • Chromosome 1 Open Reading Frame 138 2
  • ADAMTSL4 Antisense Gene Protein 1 4

External Ids for ADAMTSL4-AS1 Gene

Previous HGNC Symbols for ADAMTSL4-AS1 Gene

  • C1orf138

Previous GeneCards Identifiers for ADAMTSL4-AS1 Gene

  • GC01M150533

Summaries for ADAMTSL4-AS1 Gene

GeneCards Summary for ADAMTSL4-AS1 Gene

ADAMTSL4-AS1 (ADAMTSL4 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for ADAMTSL4-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAMTSL4-AS1 Gene

Genomics for ADAMTSL4-AS1 Gene

GeneHancer (GH) Regulatory Elements for ADAMTSL4-AS1 Gene

Promoters and enhancers for ADAMTSL4-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J150514 Promoter/Enhancer 1.5 Ensembl ENCODE 12.2 +58.7 58738 2.7 HDGF PKNOX1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B SLC30A9 FALEC GC01P150516 ADAMTSL4 MRPS21 PIP5K1A SETDB1 CYCSP51 C1orf56 LOC100289061 ADAMTSL4-AS1
GH01J150507 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 11.6 +66.1 66082 2.3 HDGF HDAC1 PTBP1 NFXL1 POLR2B GLIS2 E2F8 ZNF366 SMARCC2 ZFP91 ECM1 PRPF3 PI4KB MRPS21 ADAMTSL4 RPRD2 SETDB1 ZNF687 GABPB2 POGZ
GH01J150476 Enhancer 0.9 Ensembl ENCODE 11.5 +96.9 96866 2.2 HDAC1 MEIS2 LEF1 FOXA2 ZNF133 FEZF1 ZBTB7B ZFHX2 MTA3 CTBP1 ECM1 MRPS21 ADAMTSL4 LOC100289061 ADAMTSL4-AS1 PIP5K1A APH1A C1orf54 PI4KB GABPB2
GH01J150472 Enhancer 0.9 ENCODE 11.5 +100.9 100923 1.6 FOXA2 ARID4B ZNF48 YY1 NFKBIZ RXRA SP5 PPARG KAT8 NFIL3 ADAMTSL4 ECM1 LOC100289061 ADAMTSL4-AS1 APH1A C1orf54 HORMAD1 PRUNE1 RNU6-884P TARS2
GH01J150484 Enhancer 0.9 Ensembl ENCODE 11.1 +89.7 89669 0.8 GTF2F1 CTCF RAD21 E2F1 FOSL1 CC2D1A NCOR1 BRD9 ARID2 VEZF1 ECM1 ADAMTSL4 LOC100289061 ADAMTSL4-AS1 PRPF3 APH1A C1orf54 CA14 UBE2D3P3 CTSK
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADAMTSL4-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ADAMTSL4-AS1 Gene

Genomic Locations for ADAMTSL4-AS1 Gene
chr1:150,560,202-150,574,552
(GRCh38/hg38)
Size:
14,351 bases
Orientation:
Minus strand
chr1:150,533,480-150,533,969
(GRCh37/hg19)
Size:
490 bases
Orientation:
Minus strand

Genomic View for ADAMTSL4-AS1 Gene

Genes around ADAMTSL4-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAMTSL4-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAMTSL4-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAMTSL4-AS1 Gene

Proteins for ADAMTSL4-AS1 Gene

  • Protein details for ADAMTSL4-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T5F5-A4AS1_HUMAN
    Recommended name:
    Uncharacterized protein ADAMTSL4-AS1
    Protein Accession:
    Q5T5F5
    Secondary Accessions:
    • Q6ZS69

    Protein attributes for ADAMTSL4-AS1 Gene

    Size:
    129 amino acids
    Molecular mass:
    14090 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ADAMTSL4-AS1 Gene

Post-translational modifications for ADAMTSL4-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAMTSL4-AS1 Gene

Domains & Families for ADAMTSL4-AS1 Gene

Protein Domains for ADAMTSL4-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAMTSL4-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAMTSL4-AS1 Gene

Function for ADAMTSL4-AS1 Gene

Phenotypes From GWAS Catalog for ADAMTSL4-AS1 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADAMTSL4-AS1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAMTSL4-AS1 Gene

Localization for ADAMTSL4-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ADAMTSL4-AS1 gene
Compartment Confidence
extracellular 2
cytosol 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ADAMTSL4-AS1 Gene

Pathways & Interactions for ADAMTSL4-AS1 Gene

SuperPathways for ADAMTSL4-AS1 Gene

No Data Available

Interacting Proteins for ADAMTSL4-AS1 Gene

Gene Ontology (GO) - Biological Process for ADAMTSL4-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAMTSL4-AS1 Gene

Drugs & Compounds for ADAMTSL4-AS1 Gene

No Compound Related Data Available

Transcripts for ADAMTSL4-AS1 Gene

mRNA/cDNA for ADAMTSL4-AS1 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(1) RNA Central transcripts :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADAMTSL4-AS1

Alternative Splicing Database (ASD) splice patterns (SP) for ADAMTSL4-AS1 Gene

No ASD Table

Relevant External Links for ADAMTSL4-AS1 Gene

GeneLoc Exon Structure for
ADAMTSL4-AS1
ECgene alternative splicing isoforms for
ADAMTSL4-AS1

Expression for ADAMTSL4-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADAMTSL4-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ADAMTSL4-AS1 Gene

This gene is overexpressed in Whole Blood (x19.6).

Evidence on tissue expression from TISSUES for ADAMTSL4-AS1 Gene

  • Nervous system(4.4)
genes like me logo Genes that share expression patterns with ADAMTSL4-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAMTSL4-AS1 Gene

Orthologs for ADAMTSL4-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ADAMTSL4-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ADAMTSL4-AS1 34
  • 97 (a)
OneToOne
Species where no ortholog for ADAMTSL4-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ADAMTSL4-AS1 Gene

ENSEMBL:
Gene Tree for ADAMTSL4-AS1 (if available)
TreeFam:
Gene Tree for ADAMTSL4-AS1 (if available)

Paralogs for ADAMTSL4-AS1 Gene

No data available for Paralogs for ADAMTSL4-AS1 Gene

Variants for ADAMTSL4-AS1 Gene

Sequence variations from dbSNP and Humsavar for ADAMTSL4-AS1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs111660862 likely-benign, Ectopia lentis 150,560,949(-) T/A non_coding_transcript_variant
rs114181942 uncertain-significance, Ectopia lentis 150,560,491(-) G/C downstream_transcript_variant
rs181259344 uncertain-significance, Ectopia lentis 150,560,472(-) G/A downstream_transcript_variant
rs35531650 uncertain-significance, Ectopia lentis 150,560,832(-) C/A downstream_transcript_variant
rs587633776 uncertain-significance, Ectopia lentis 150,560,529(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ADAMTSL4-AS1 Gene

Variant ID Type Subtype PubMed ID
esv3587506 CNV loss 21293372
nsv1006838 CNV gain 25217958
nsv527379 CNV loss 19592680

Variation tolerance for ADAMTSL4-AS1 Gene

Gene Damage Index Score: 1.41; 27.75% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ADAMTSL4-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADAMTSL4-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADAMTSL4-AS1 Gene

Disorders for ADAMTSL4-AS1 Gene

Additional Disease Information for ADAMTSL4-AS1

No disorders were found for ADAMTSL4-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAMTSL4-AS1 Gene

Publications for ADAMTSL4-AS1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ADAMTSL4-AS1 Gene

Sources for ADAMTSL4-AS1 Gene

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