Aliases for ADAMTS19 Gene
External Ids for ADAMTS19 Gene
Previous GeneCards Identifiers for ADAMTS19 Gene
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADAMTS19 Gene
ADAMTS19 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 19) is a Protein Coding gene. Diseases associated with ADAMTS19 include Discrete Subaortic Stenosis and Subvalvular Aortic Stenosis. Among its related pathways are Metabolism of proteins and O-glycosylation of TSR domain-containing proteins. Gene Ontology (GO) annotations related to this gene include peptidase activity and metalloendopeptidase activity. An important paralog of this gene is ADAMTS17.