Aliases for ADAMTS16 Gene
External Ids for ADAMTS16 Gene
Previous GeneCards Identifiers for ADAMTS16 Gene
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016]
GeneCards Summary for ADAMTS16 Gene
ADAMTS16 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 16) is a Protein Coding gene. Diseases associated with ADAMTS16 include Weill-Marchesani Syndrome and Cryptorchidism, Unilateral Or Bilateral. Among its related pathways are Degradation of the extracellular matrix and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include peptidase activity and metalloendopeptidase activity. An important paralog of this gene is ADAMTS18.