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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal T... See more...
Aliases for ADAMTS15 Gene
Aliases for ADAMTS15 Gene
- ADAM Metallopeptidase With Thrombospondin Type 1 Motif 15 2 3 5
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs 15 3 4
- A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 15, Preproprotein 3
- A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 15 2
- Metalloprotease Disintegrin 15 With Thrombospondin Domains 3
- EC 3.4.24.82 51
External Ids for ADAMTS15 Gene
- HGNC: 16305
- NCBI Entrez Gene: 170689
- Ensembl: ENSG00000166106
- OMIM®: 607509
- UniProtKB/Swiss-Prot: Q8TE58
Previous GeneCards Identifiers for ADAMTS15 Gene
- GC11P132319
- GC11P131831
- GC11P130352
- GC11P129856
- GC11P129824
- GC11P126273
- GC11P130318
Summaries for ADAMTS15 Gene
-
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which may play a role in versican processing during skeletal muscle development. This gene may function as a tumor suppressor in colorectal and breast cancers. [provided by RefSeq, May 2016]
GeneCards Summary for ADAMTS15 Gene
ADAMTS15 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 15) is a Protein Coding gene. Diseases associated with ADAMTS15 include Thrombocytopenia, Paris-Trousseau Type and Jacobsen Syndrome. Among its related pathways are O-linked glycosylation and Diseases of glycosylation. Gene Ontology (GO) annotations related to this gene include metalloendopeptidase activity. An important paralog of this gene is ADAMTS1.
Additional gene information for ADAMTS15 Gene
- HGNC (16305)
- NCBI Entrez Gene (170689)
- Ensembl (ENSG00000166106)
- OMIM® (607509)
- UniProtKB/Swiss-Prot (Q8TE58)
- Open Targets Platform(ENSG00000166106)
- Search for ADAMTS15 at DataMed
- Search for ADAMTS15 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ADAMTS15 Gene
Genomics for ADAMTS15 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ADAMTS15 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ADAMTS15 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ADAMTS15
- Top Transcription factor binding sites by QIAGEN in the ADAMTS15 gene promoter:
-
- ER-alpha
- FOXL1
- FOXO3
- FOXO3a
- FOXO3b
- Lmo2
- STAT1
- STAT1alpha
- STAT1beta
- ZID
Genomic Locations for ADAMTS15 Gene
Latest Assembly
- chr11:130,448,645-130,478,215
- (GRCh38/hg38)
- Size:
- 29,571 bases
- Orientation:
- Plus strand
Previous Assembly
- chr11:130,318,540-130,346,540
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 28,001 bases
- Orientation:
- Plus strand
- chr11:130,318,869-130,346,532
- (GRCh37/hg19 by Ensembl)
- Size:
- 27,664 bases
- Orientation:
- Plus strand
Genomic View for ADAMTS15 Gene
Genes around ADAMTS15 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q24.3 by HGNC
- 11q24.3 by Entrez Gene
- 11q24.3 by Ensembl
ADAMTS15 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADAMTS15 Gene
Proteins for ADAMTS15 Gene
-
Protein details for ADAMTS15 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TE58-ATS15_HUMAN
- Recommended name:
- A disintegrin and metalloproteinase with thrombospondin motifs 15
- Protein Accession:
- Q8TE58
- Q32MI6
Protein attributes for ADAMTS15 Gene
- Size:
- 950 amino acids
- Molecular mass:
- 103287 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
- No Data Available
Protein Expression for ADAMTS15 Gene
Selected DME Specific Peptides for ADAMTS15 Gene
- Q8TE58:
-
- VETLVVAD
- DTAILFTRQ
- VIEDDGL
- CSRTCGGGV
- SCSVIED
- CDTLGMADVGT
- HFPWADGTSCGEGK
- GTMCDPK
- DKCGVCGG
- AHELGHVF
Post-translational modifications for ADAMTS15 Gene
- The precursor is cleaved by a furin endopeptidase.
- Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion (By similarity).
-
Glycosylation at Asn141, Asn591, Asn623, and Asn679
- NX_Q8TE58 (NX_Q8TE58-1)
- Modification sites at PhosphoSitePlus
Other Protein References for ADAMTS15 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for ADAMTS15
- Novus Biologicals Antibodies for ADAMTS15
-
Abcam antibodies for ADAMTS15
- Invitrogen Antibodies for ADAMTS15 (AFLGC-ADAMTS15)
-
Santa Cruz Biotechnology (SCBT) Antibodies for ADAMTS15
- Sino Biological Antibodies for ADAMTS15
Protein products for research
-
OriGene Purified Proteins for ADAMTS15
- Search Origene for MassSpec and Protein Over-expression Lysates for ADAMTS15
- Origene Custom Protein Services for ADAMTS15
- antibodies-online: Show 3 available ADAMTS15 Proteins ranked by validation data
- Compare Top ADAMTS15 Proteins
-
Quality Products:
-
Abcam proteins for ADAMTS15
Domains & Families for ADAMTS15 Gene
Gene Families for ADAMTS15 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for ADAMTS15 Gene
- InterPro:
- Blocks:
-
- Thrombospondin, type I
- Disintegrin
- Thrombospondin type 1 repeat signature
- Metalloendopeptidase M12B
- ADAM-TS Spacer 1
- ProtoNet:
Suggested Antigen Peptide Sequences for ADAMTS15 Gene
- GenScript: Design optimal peptide antigens:
-
- A disintegrin and metalloproteinase with thrombospondin motifs 15 (ATS15_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8TE58UniProtKB/Swiss-Prot:
ATS15_HUMAN :- The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellular matrix.
- Domain:
-
- The spacer domain and the TSP type-1 domains are important for a tight interaction with the extracellular matrix.
- The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Function for ADAMTS15 Gene
Enzyme Numbers (IUBMB) for ADAMTS15 Gene
Phenotypes From GWAS Catalog for ADAMTS15 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004175 | endopeptidase activity | IEA | -- |
| GO:0004222 | metalloendopeptidase activity | IBA | 21873635 |
| GO:0008201 | heparin binding | IEA | -- |
| GO:0008233 | peptidase activity | IEA | -- |
| GO:0008237 | metallopeptidase activity | IEA | -- |
Phenotypes for ADAMTS15 Gene
- MGI mutant phenotypes for ADAMTS15:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ADAMTS15:
Animal Models for ADAMTS15 Gene
- MGI Knock Outs for ADAMTS15:
-
- Adamts15 Adamts15<tm1.1(KOMP)Vlcg>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ADAMTS15 - Starting at $85 >
- * ADAMTS15 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ADAMTS15
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ADAMTS15
-
Santa Cruz Biotechnology (SCBT) CRISPR for ADAMTS15
miRNA for ADAMTS15 Gene
- miRTarBase miRNAs that target ADAMTS15
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ADAMTS15
- Browse OriGene Inhibitory RNA Products For ADAMTS15
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Clone products for research
- Applied Biological Materials (abm): Clones for ADAMTS15 - Starting at $45 >
- * ADAMTS15 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ADAMTS15
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ADAMTS15
Cell Lines for research
-
Horizon Cell Lines for ADAMTS15
No data available for Molecular function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ADAMTS15 Gene
Localization for ADAMTS15 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ADAMTS15 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| plasma membrane | 3 |
| cytosol | 2 |
| cytoskeleton | 1 |
| nucleus | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005615 | extracellular space | IEA | -- |
| GO:0009986 | cell surface | IEA | -- |
| GO:0031012 | extracellular matrix | IBA | 21873635 |
| GO:0062023 | collagen-containing extracellular matrix | IEA | -- |
Pathways & Interactions for ADAMTS15 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | O-glycosylation of TSR domain-containing proteins | ||
| 2 | Diseases of glycosylation | ||
| 3 | Metabolism of proteins | ||
| 4 | HIV Life Cycle |
.45
|
|
| 5 | O-linked glycosylation | ||
Pathways by source for ADAMTS15 Gene
8 Reactome pathways for ADAMTS15 Gene
Interacting Proteins for ADAMTS15 Gene
GPS-Prot Interaction Network for ADAMTS15
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA | -- |
| GO:0030198 | extracellular matrix organization | IBA | 21873635 |
No data available for SIGNOR curated interactions for ADAMTS15 Gene
Transcripts for ADAMTS15 Gene
mRNA/cDNA for ADAMTS15 Gene
- 1 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000299164 5673 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for ADAMTS15 - Starting at $85 >
- * ADAMTS15 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for ADAMTS15
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ADAMTS15
-
Santa Cruz Biotechnology (SCBT) CRISPR for ADAMTS15
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ADAMTS15
- Browse OriGene Inhibitory RNA Products For ADAMTS15
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADAMTS15
Clone products for research
- Applied Biological Materials (abm): Clones for ADAMTS15 - Starting at $45 >
- * ADAMTS15 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for ADAMTS15
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ADAMTS15
Relevant External Links for ADAMTS15 Gene
- GeneLoc Exon Structure for
- ADAMTS15
Expression for ADAMTS15 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Cartilage (Muscoskeletal System)
- Intervertebral Disc Annulus Fibrosus Cells Annulus Fibrosus
-
Heart (Cardiovascular System)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for ADAMTS15 Gene
This gene is overexpressed in Adipose - Visceral (Omentum) (x4.6).
This gene is overexpressed in Heart (68.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ADAMTS15 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ADAMTS15
SOURCE GeneReport for Unigene cluster for ADAMTS15 Gene:
Hs.534221mRNA Expression by UniProt/SwissProt for ADAMTS15 Gene:
Q8TE58-ATS15_HUMAN
Tissue specificity:
Expressed in fetal liver and kidney, but not in any of the adult tissues examined.
Primer products for research
-
OriGene qPCR primer pairs for ADAMTS15
Gene Expression Assays for research
No data available for Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAMTS15 Gene
Orthologs for ADAMTS15 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ADAMTS15 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ADAMTS15 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ADAMTS15 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Adamts15 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Adamts15 30 17 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ADAMTS15 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ADAMTS15 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ADAMTS15 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ADAMTS15 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | adamts15 30 |
|
||
| Str.13514 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | adamts15b 31 |
|
OneToMany | |
| adamts15a 31 |
|
OneToMany |
- Species where no ortholog for ADAMTS15 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for ADAMTS15 Gene
- ENSEMBL:
- Gene Tree for ADAMTS15 (if available)
- TreeFam:
- Gene Tree for ADAMTS15 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ADAMTS15: view image
Paralogs for ADAMTS15 Gene
Paralogs for ADAMTS15 Gene
(9) SIMAP similar genes for ADAMTS15 Gene using alignment to 1 proteins:
- ATS15_HUMAN
Variants for ADAMTS15 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ADAMTS15 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs61744317 | Benign: not provided | 130,473,807(+) |
C/T NM_139055.3(ADAMTS15):c.2839C>T (p.Leu947=) |
SYNONYMOUS | |
| rs61746092 | Benign: not provided | 130,473,128(+) |
C/T NM_139055.3(ADAMTS15):c.2160C>T (p.Ile720=) |
SYNONYMOUS | |
| rs61753090 | Benign: not provided | 130,449,676(+) |
G/A NM_139055.3(ADAMTS15):c.703G>A (p.Gly235Ser) |
MISSENSE | |
| rs61753091 | Benign: not provided | 130,473,248(+) |
C/T NM_139055.3(ADAMTS15):c.2280C>T (p.Ser760=) |
SYNONYMOUS | |
| rs61757474 | Benign: not provided | 130,473,473(+) |
G/A NM_139055.3(ADAMTS15):c.2505G>A (p.Pro835=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
74% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.36;
76.86% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ADAMTS15 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADAMTS15 Gene
Disorders for ADAMTS15 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| thrombocytopenia, paris-trousseau type |
|
|
| jacobsen syndrome |
|
|
| splenomegaly |
|
|
| deficiency anemia |
|
|
| strabismus |
|
|
Search ADAMTS15 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ADAMTS15
- Genetic Association Database
- (GAD)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ADAMTS15 Gene
Publications for ADAMTS15 Gene
- Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains. (PMID: 11867212) Cal S … López-Otín C (Gene 2002) 2 3 4
- Genetic inactivation of ADAMTS15 metalloprotease in human colorectal cancer. (PMID: 19458070) Viloria CG … López-Otín C (Cancer research 2009) 3 23
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition. (PMID: 30631154) Hu Q … Yang L (Cell research 2019) 3
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
ExternalLinks
Products for ADAMTS15 Gene
- Custom Antibody ServicesOriGene Antibodies for ADAMTS15
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- Custom Assay Services
- OriGene Purified Proteins for ADAMTS15
- Search Origene for MassSpec and Protein Over-expression Lysates for ADAMTS15
- Origene Custom Protein Services for ADAMTS15
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ADAMTS15
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- OriGene qPCR primer pairs for ADAMTS15
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- Sino Biological Human cDNA Clone for ADAMTS15
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ADAMTS15
- Novus Biologicals proteins and lysates for ADAMTS15
- Browse Antibodies
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- Browse Primary Antibodies
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- Browse Proteins and Peptides
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- Browse Recombinant Antibodies
- Invitrogen Antibodies for ADAMTS15 (AFLGC-ADAMTS15)
- VectorBuilder Custom and pre-made DNA vectors for ADAMTS15 (ie. gene expression, shRNA knockdown, CRISPR)
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- VectorBuilder Stable cell line generation for ADAMTS15
- antibodies-online: Show 33 available ADAMTS15 Antibodies ranked by validation data
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- antibodies-online: Show 16 available ADAMTS15 Elisa Kits ranked by validation data
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- antibodies-online: Show 3 available ADAMTS15 Proteins ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for ADAMTS15
- Search Santa Cruz Biotechnology (SCBT) for ADAMTS15 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ADAMTS15
- Horizon Cell Lines for ADAMTS15
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ADAMTS15
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ADAMTS15
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ADAMTS15
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Sources for ADAMTS15 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
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- (55) TGDB
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- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
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- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
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- (115) NCBI Bookshelf
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- (118) HPO
- (119) UDN
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- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
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- (130) CIViC
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- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB