Aliases for ADAM6 Gene

Aliases for ADAM6 Gene

  • ADAM Metallopeptidase Domain 6 (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 6 2 3
  • TMDCIV 2 3
  • Metalloprotease-Like, Disintegrin-Like Protein Pseudogene 3
  • ADAM Metallopeptidase Domain 6, Pseudogene 2
  • Chromosome 14 Open Reading Frame 96 2
  • ADAM Metallopeptidase Domain 6 2
  • C14orf96 3
  • ADAM6 5

External Ids for ADAM6 Gene

Previous HGNC Symbols for ADAM6 Gene

  • C14orf96

Previous GeneCards Identifiers for ADAM6 Gene

  • GC00U990447
  • GC14U900437
  • GC14M105506
  • GC14M106435
  • GC14M086568

Summaries for ADAM6 Gene

GeneCards Summary for ADAM6 Gene

ADAM6 (ADAM Metallopeptidase Domain 6 (Pseudogene)) is a Pseudogene.

Additional gene information for ADAM6 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ADAM6 Gene

Genomics for ADAM6 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ADAM6 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J105975 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.7 -2.9 -2931 0.8 CTCF REST ZNF444 VEZF1 MAZ RAD21 TRIM22 GLIS2 ADAM6 lnc-BRF1-14 RPS8P1 IGHV1-2 IGHV6-1 lnc-TMEM121-2 NONHSAG016150.2 COPDA1 lnc-BRF1-23 lnc-BRF1-42
GH14J105967 Enhancer 0.3 Ensembl 0.7 +3.7 3668 2.8 SCRT2 SPI1 ADAM6 lnc-BRF1-14 piR-48553-114 IGHV1-2 IGHV6-1 lnc-TMEM121-2 NONHSAG016150.2 COPDA1 lnc-BRF1-23 lnc-BRF1-42
GH14J105966 Enhancer 0.2 Ensembl 0.4 +6.0 5968 0.2 piR-48553-114 ADAM6 lnc-BRF1-14 IGHV1-2 IGHV6-1 lnc-TMEM121-2 NONHSAG016150.2 COPDA1 lnc-BRF1-23 lnc-BRF1-42
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADAM6 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the ADAM6 gene promoter:
  • Cart-1
  • ER-alpha
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v3
  • Nkx3-1 v4
  • Pax-5
  • SRF
  • SRF (504 AA)

Genomic Locations for ADAM6 Gene

Genomic Locations for ADAM6 Gene
2,541 bases
Minus strand
2,540 bases
Minus strand

Genomic View for ADAM6 Gene

Genes around ADAM6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM6 Gene

Proteins for ADAM6 Gene

No data available for DME Specific Peptides for ADAM6 Gene

Domains & Families for ADAM6 Gene

Gene Families for ADAM6 Gene

genes like me logo Genes that share domains with ADAM6: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ADAM6 Gene

Function for ADAM6 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAM6 Gene

Localization for ADAM6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ADAM6 Gene

Pathways & Interactions for ADAM6 Gene

PathCards logo

SuperPathways for ADAM6 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ADAM6 Gene


No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ADAM6 Gene

Drugs & Compounds for ADAM6 Gene

No Compound Related Data Available

Transcripts for ADAM6 Gene

mRNA/cDNA for ADAM6 Gene

4 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM6 Gene

No ASD Table

Relevant External Links for ADAM6 Gene

GeneLoc Exon Structure for

Expression for ADAM6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ADAM6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

  • Testis (Reproductive System)

mRNA differential expression in normal tissues according to GTEx for ADAM6 Gene

This gene is overexpressed in Testis (x52.8).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ADAM6

SOURCE GeneReport for Unigene cluster for ADAM6 Gene:

genes like me logo Genes that share expression patterns with ADAM6: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAM6 Gene

Orthologs for ADAM6 Gene

Evolution for ADAM6 Gene

Gene Tree for ADAM6 (if available)
Gene Tree for ADAM6 (if available)

No data available for Orthologs for ADAM6 Gene

Paralogs for ADAM6 Gene

No data available for Paralogs for ADAM6 Gene

Variants for ADAM6 Gene

Structural Variations from Database of Genomic Variants (DGV) for ADAM6 Gene

Variant ID Type Subtype PubMed ID
dgv1982n100 CNV gain 25217958
dgv1985n100 CNV loss 25217958
dgv1995n100 CNV gain 25217958
dgv1996n100 CNV loss 25217958
dgv2004n100 CNV gain 25217958
dgv2005n100 CNV gain 25217958
dgv2012n100 CNV gain 25217958
dgv2013n100 CNV loss 25217958
dgv2014n100 CNV gain 25217958
dgv2015n100 CNV loss 25217958
dgv2016n100 CNV loss 25217958
dgv2017n100 CNV gain 25217958
dgv2018n100 CNV loss 25217958
dgv2019n100 CNV loss 25217958
dgv2020n100 CNV gain 25217958
dgv2021n100 CNV loss 25217958
dgv2022n100 CNV loss 25217958
dgv2023n100 CNV loss 25217958
dgv2024n100 CNV gain+loss 25217958
dgv2025n100 CNV gain 25217958
dgv2026n100 CNV loss 25217958
dgv2027n100 CNV loss 25217958
dgv2028n100 CNV gain 25217958
dgv2029n100 CNV gain 25217958
dgv2031n100 CNV loss 25217958
dgv2032n100 CNV loss 25217958
dgv27n68 CNV gain+loss 17160897
dgv392n67 CNV loss 20364138
dgv394n67 CNV loss 20364138
dgv423e199 CNV deletion 23128226
esv1001368 CNV loss 20482838
esv1002625 CNV gain 20482838
esv27023 CNV gain+loss 19812545
esv2749327 CNV deletion 23290073
esv2749328 CNV deletion 23290073
esv2760346 CNV gain+loss 21179565
esv29981 CNV gain 17803354
esv32669 CNV gain+loss 17666407
esv3568731 CNV gain 25503493
esv3581458 CNV loss 25503493
esv3581459 CNV loss 25503493
esv3581461 CNV loss 25503493
esv3635665 CNV loss 21293372
esv3892583 CNV gain 25118596
esv3892584 CNV gain 25118596
esv3892585 CNV gain 25118596
nsv1036179 CNV gain+loss 25217958
nsv1039720 CNV gain 25217958
nsv1047682 CNV gain+loss 25217958
nsv1048883 CNV loss 25217958
nsv1050165 CNV gain+loss 25217958
nsv1052391 CNV gain 25217958
nsv1052873 CNV gain+loss 25217958
nsv1053673 CNV loss 25217958
nsv1054255 CNV loss 25217958
nsv1443 CNV deletion 18451855
nsv436179 CNV deletion 17901297
nsv436184 CNV deletion 17901297
nsv456477 CNV loss 19166990
nsv471673 CNV gain+loss 15918152
nsv511038 OTHER complex 20534489
nsv511534 CNV gain 21212237
nsv517055 CNV gain+loss 19592680
nsv566351 CNV loss 21841781
nsv566486 CNV loss 21841781
nsv817649 CNV loss 17921354
nsv819133 CNV gain 19587683
nsv821677 CNV gain 15273396
nsv827099 CNV loss 20364138
nsv827138 CNV loss 20364138
nsv827147 CNV loss 20364138
nsv827155 CNV loss 20364138
nsv832895 CNV gain+loss 17160897
nsv974376 CNV duplication 23825009
nsv974377 CNV duplication 23825009
nsv976376 CNV duplication 23825009
nsv977508 CNV duplication 23825009

Additional Variant Information for ADAM6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for ADAM6 Gene

Disorders for ADAM6 Gene

Additional Disease Information for ADAM6

No disorders were found for ADAM6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM6 Gene

Publications for ADAM6 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  2. Comparative genomic analysis of human and chimpanzee proteases. (PMID: 16162398) Puente XS … López-Otín C (Genomics 2005) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  4. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F … Honjo T (The Journal of experimental medicine 1998) 3

Products for ADAM6 Gene

Sources for ADAM6 Gene