Aliases for ADAM32 Gene
External Ids for ADAM32 Gene
Previous GeneCards Identifiers for ADAM32 Gene
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
GeneCards Summary for ADAM32 Gene
ADAM32 (ADAM Metallopeptidase Domain 32) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include metalloendopeptidase activity. An important paralog of this gene is ADAM18.
UniProtKB/Swiss-Prot Summary for ADAM32 Gene
May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.