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Aliases for ADAM1A Gene

Aliases for ADAM1A Gene

  • ADAM Metallopeptidase Domain 1A (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 1 (Fertilin Alpha) Pseudogene 2 3
  • ADAM Metallopeptidase Domain 1, Pseudogene 2 3
  • Fertilin Alpha 2 3
  • A Disintegrin And Metalloproteinase Domain 1 ( Fertilin Alpha) 3
  • ADAM Metallopeptidase Domain 1 (Fertilin Alpha) Pseudogene 3
  • ADAM Metallopeptidase Domain 1A, Pseudogene 2
  • ADAM1P 3
  • PH-30a 3
  • FTNAP 3
  • ADAM1 3
  • Ftna 3

External Ids for ADAM1A Gene

Previous HGNC Symbols for ADAM1A Gene

  • ADAM1

Previous GeneCards Identifiers for ADAM1A Gene

  • GC12P112340
  • GC12P112344
  • GC12P112351
  • GC12P112357

Summaries for ADAM1A Gene

GeneCards Summary for ADAM1A Gene

ADAM1A (ADAM Metallopeptidase Domain 1A (Pseudogene)) is a Pseudogene.

Additional gene information for ADAM1A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM1A Gene

Genomics for ADAM1A Gene

GeneHancer (GH) Regulatory Elements for ADAM1A Gene

Promoters and enhancers for ADAM1A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J111402 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 28.6 -490.1 -490070 13.1 HDGF ZNF652 SP1 CC2D1A ZFX ELF3 ZKSCAN8 MNT CBFA2T2 ZNF148 SH2B3 ATXN2 ADAM1A HSPA8P14 HECTD4 ARPC3 MAPKAPK5 RPS2P41 PHETA1 ALDH2
GH12J111424 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 35.7 -463.0 -462999 23.7 SP1 ZNF121 CEBPG ZNF687 MAFK TRIM24 SP7 RELA PPARG POLR2A PIR45326 ADAM1A SH2B3 MAPKAPK5 PCNPP1 ATXN2 PHETA1 HECTD4 ALDH2 TMEM116
GH12J112417 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 31.6 +520.0 520038 3 CTCF ZFX ELF3 MNT SIX5 NKRF POLR2A MLLT1 CEBPG GTF2F1 ATXN2 PTPN11 RPL6 ADAM1A PCNPP1 TMEM116 GC12M112409
GH12J112407 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 30.8 +509.7 509670 3 ELF3 ZFX SIX5 NKRF POLR2A MLLT1 ZNF121 GTF2F1 CSDE1 ZNF384 RPL6 ADAM1A MAPKAPK5 DDX54 SLC8B1 ERP29 RPS2P41 TMEM116 PTPN11 GC12M112409
GH12J111055 Enhancer 1.9 VISTA UCNEbase FANTOM5 ENCODE 24.2 -841.9 -841872 2.9 ZNF473 KLF14 ZNF548 MLLT1 EGR1 ZNF547 IKZF1 CREB1 ZNF600 IKZF2 ADAM1A ATXN2 IFT81 MAPKAPK5 PCNPP1 CUX2 BRAP ATXN2-AS ANAPC7 MYL2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADAM1A on UCSC Golden Path with GeneCards custom track

Genomic Locations for ADAM1A Gene

Genomic Locations for ADAM1A Gene
chr12:111,899,063-111,901,902
(GRCh38/hg38)
Size:
2,840 bases
Orientation:
Plus strand
chr12:112,336,867-112,340,042
(GRCh37/hg19)
Size:
3,176 bases
Orientation:
Plus strand

Genomic View for ADAM1A Gene

Genes around ADAM1A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM1A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM1A Gene

Proteins for ADAM1A Gene

Post-translational modifications for ADAM1A Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAM1A Gene

Domains & Families for ADAM1A Gene

Gene Families for ADAM1A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAM1A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAM1A Gene

Function for ADAM1A Gene

Phenotypes From GWAS Catalog for ADAM1A Gene

Animal Model Products

CRISPR Products

miRNA for ADAM1A Gene

miRTarBase miRNAs that target ADAM1A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ADAM1A Gene

Localization for ADAM1A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ADAM1A Gene

Pathways & Interactions for ADAM1A Gene

PathCards logo

SuperPathways for ADAM1A Gene

No Data Available

Interacting Proteins for ADAM1A Gene

Gene Ontology (GO) - Biological Process for ADAM1A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAM1A Gene

Drugs & Compounds for ADAM1A Gene

No Compound Related Data Available

Transcripts for ADAM1A Gene

mRNA/cDNA for ADAM1A Gene

(2) Additional mRNA sequences :
(32) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for ADAM1A Gene

ADAM metallopeptidase domain 1A, pseudogene:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM1A Gene

No ASD Table

Relevant External Links for ADAM1A Gene

GeneLoc Exon Structure for
ADAM1A
ECgene alternative splicing isoforms for
ADAM1A

Expression for ADAM1A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADAM1A Gene

NURSA nuclear receptor signaling pathways regulating expression of ADAM1A Gene:

ADAM1A

SOURCE GeneReport for Unigene cluster for ADAM1A Gene:

Hs.661708
genes like me logo Genes that share expression patterns with ADAM1A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAM1A Gene

Orthologs for ADAM1A Gene

Evolution for ADAM1A Gene

ENSEMBL:
Gene Tree for ADAM1A (if available)
TreeFam:
Gene Tree for ADAM1A (if available)

No data available for Orthologs for ADAM1A Gene

Paralogs for ADAM1A Gene

No data available for Paralogs for ADAM1A Gene

Variants for ADAM1A Gene

Sequence variations from dbSNP and Humsavar for ADAM1A Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1001022541 -- 111,897,199(+) A/G upstream_transcript_variant
rs1001074655 -- 111,897,494(+) T/C upstream_transcript_variant
rs1001155966 -- 111,897,841(+) T/TT upstream_transcript_variant
rs1001273482 -- 111,899,782(+) T/C non_coding_transcript_variant
rs1001477609 -- 111,898,325(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ADAM1A Gene

Variant ID Type Subtype PubMed ID
esv1010936 CNV deletion 20482838
nsv1044606 CNV gain 25217958
nsv1045488 CNV gain 25217958

Additional Variant Information for ADAM1A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADAM1A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADAM1A Gene

Disorders for ADAM1A Gene

Additional Disease Information for ADAM1A

No disorders were found for ADAM1A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM1A Gene

Publications for ADAM1A Gene

  1. The human fertilin alpha gene is non-functional: implications for its proposed role in fertilization. (PMID: 9032439) Jury JA … Hall L (The Biochemical journal 1997) 2 3 23 58
  2. The transmembrane homotrimer of ADAM 1 in model lipid bilayers. (PMID: 17189481) Gan SW … Torres J (Protein science : a publication of the Protein Society 2007) 23 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. The mechanism of sperm-oocyte fusion in mammals. (PMID: 15047933) Kaji K … Kudo A (Reproduction (Cambridge, England) 2004) 23 58
  5. Positive selection within sperm-egg adhesion domains of fertilin: an ADAM gene with a potential role in fertilization. (PMID: 12519902) Civetta A (Molecular biology and evolution 2003) 23 58

Products for ADAM1A Gene

Sources for ADAM1A Gene

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