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ADAL (Adenosine Deaminase Like) is a Protein Coding gene. Diseases associated with ADAL include Hypertropia and Spastic Hemiplegia. Among its related pathways are Metabolism of nucleotides and Abacavir transport and metabolism. Gene Ontology (GO) annotations related to this gene include adenosine deaminase activity and deaminase activity. An important paralog of this gene is ADA.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004000 | adenosine deaminase activity | IBA | 21873635 |
GO:0016787 | hydrolase activity | IEA | -- |
GO:0019239 | deaminase activity | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005829 | cytosol | TAS | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Metabolism of nucleotides |
.01
|
|
2 | Abacavir transport and metabolism | ||
3 | Metabolism |
.40
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006154 | adenosine catabolic process | IBA | 21873635 |
GO:0009117 | nucleotide metabolic process | IEA | -- |
GO:0017144 | drug metabolic process | TAS | -- |
GO:0043101 | purine-containing compound salvage | TAS | -- |
GO:0046103 | inosine biosynthetic process | IBA | 21873635 |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ADAL 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ADAL 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ADAL 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Adal 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | ADAL 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | ADAL 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | ADAL 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ADAL 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | adal 30 |
|
||
Str.12484 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | adal 30 31 |
|
OneToOne | |
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005158 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | Ada 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | C44B7.12 30 31 |
|
OneToOne | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT4G04880 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os07g0661000 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
Disorder | Aliases | PubMed IDs |
---|---|---|
hypertropia |
|
|
spastic hemiplegia |
|
|
lymphocytic choriomeningitis |
|
|
strabismus |
|
|