Aliases for ACYP2 Gene
External Ids for ACYP2 Gene
Previous GeneCards Identifiers for ACYP2 Gene
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
GeneCards Summary for ACYP2 Gene
ACYP2 (Acylphosphatase 2) is a Protein Coding gene. Diseases associated with ACYP2 include Polyneuropathy Due To Drug and Drug-Induced Hearing Loss. Among its related pathways are ATP/ITP metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include acylphosphatase activity. An important paralog of this gene is ACYP1.
UniProtKB/Swiss-Prot Summary for ACYP2 Gene
Its physiological role is not yet clear.