Aliases for ACYP1 Gene
External Ids for ACYP1 Gene
Previous GeneCards Identifiers for ACYP1 Gene
This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
GeneCards Summary for ACYP1 Gene
ACYP1 (Acylphosphatase 1) is a Protein Coding gene. Diseases associated with ACYP1 include Niemann-Pick Disease, Type C2 and Niemann-Pick Disease, Type C1. Among its related pathways are ATP/ITP metabolism and Naphthalene metabolism. Gene Ontology (GO) annotations related to this gene include acylphosphatase activity. An important paralog of this gene is ACYP2.
UniProtKB/Swiss-Prot Summary for ACYP1 Gene
Its physiological role is not yet clear.