Aliases for ACTRT1 Gene
External Ids for ACTRT1 Gene
Previous GeneCards Identifiers for ACTRT1 Gene
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]
GeneCards Summary for ACTRT1 Gene
UniProtKB/Swiss-Prot Summary for ACTRT1 Gene
Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression.