Aliases for ACTR10 Gene

Aliases for ACTR10 Gene

  • Actin Related Protein 10 2 3 5
  • Actin Related Protein 10 Homolog 2 3
  • Actin-Related Protein 10 3 4
  • Actin-Related Protein 11 3 4
  • HARP11 3 4
  • ACTR11 3 4
  • Actin-Related Protein 10 Homolog (S. Cerevisiae) 2
  • Arp10 3
  • Arp11 3
  • ARP11 4

External Ids for ACTR10 Gene

Previous GeneCards Identifiers for ACTR10 Gene

  • GC14P052462
  • GC14P056656
  • GC14P057736
  • GC14P058666
  • GC14P038835

Summaries for ACTR10 Gene

GeneCards Summary for ACTR10 Gene

ACTR10 (Actin Related Protein 10) is a Protein Coding gene. Diseases associated with ACTR10 include Brachydactyly, Type A3. Among its related pathways are Innate Immune System and Cell cycle_Spindle assembly and chromosome separation. An important paralog of this gene is ACTG1.

Additional gene information for ACTR10 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ACTR10 Gene

Genomics for ACTR10 Gene

GeneHancer (GH) Regulatory Elements for ACTR10 Gene

Promoters and enhancers for ACTR10 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J058199 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +0.4 421 3 RXRA MYC POLR2G SP1 ZFX POLR2A ZBTB26 TARDBP SAP30 KLF7 ACTR10 ENSG00000258682 PSMA3-AS1 ARMH4 piR-32214-190
GH14J058198 Enhancer 0.3 ENCODE 500.7 -1.8 -1802 0.2 ZBTB48 TBX21 ACTR10 lnc-ACTR10-2 ENSG00000258519 ARMH4 PSMA3-AS1
GH14J058201 Enhancer 0.3 Ensembl 500.7 -1.6 -1579 0.2 ZBTB48 TBX21 ACTR10 lnc-ACTR10-2 ENSG00000258519 ARMH4 PSMA3-AS1
GH14J058200 Enhancer 0.3 Ensembl 500.7 -2.0 -1979 0.2 TBX21 ACTR10 lnc-ACTR10-2 ENSG00000258519 ARMH4 PSMA3-AS1
GH14J058280 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 22.6 +82.3 82320 4.8 NCOR1 JUND TOE1 ATF2 TAF9B FOXA2 CEBPB NFIC SP2 ZBTB17 ACTR10 PSMA3-AS1 TOMM20L ENSG00000258682 ARID4A HMGB1P14 lnc-ARID4A-2 ARMH4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ACTR10 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ACTR10

Top Transcription factor binding sites by QIAGEN in the ACTR10 gene promoter:
  • COMP1
  • E2F
  • E2F-1
  • Evi-1
  • FOXJ2
  • FOXJ2 (long isoform)
  • HNF-4alpha2
  • RORalpha1
  • RORalpha2
  • RSRFC4

Genomic Locations for ACTR10 Gene

Genomic Locations for ACTR10 Gene
chr14:58,200,080-58,235,636
(GRCh38/hg38)
Size:
35,557 bases
Orientation:
Plus strand
chr14:58,666,798-58,702,354
(GRCh37/hg19)
Size:
35,557 bases
Orientation:
Plus strand

Genomic View for ACTR10 Gene

Genes around ACTR10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACTR10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACTR10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACTR10 Gene

Proteins for ACTR10 Gene

  • Protein details for ACTR10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NZ32-ARP10_HUMAN
    Recommended name:
    Actin-related protein 10
    Protein Accession:
    Q9NZ32
    Secondary Accessions:
    • Q9H9Y5
    • Q9NWY2

    Protein attributes for ACTR10 Gene

    Size:
    417 amino acids
    Molecular mass:
    46307 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACTR10 Gene

Post-translational modifications for ACTR10 Gene

  • Ubiquitination at Lys26, Lys44, and Lys375
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ACTR10 Gene

Domains & Families for ACTR10 Gene

Gene Families for ACTR10 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ACTR10 Gene

Blocks:
  • Actin/actin-like
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ACTR10 Gene

GenScript: Design optimal peptide antigens:
  • Actin-related protein 11 (ARP10_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NZ32

UniProtKB/Swiss-Prot:

ARP10_HUMAN :
  • Belongs to the actin family.
Family:
  • Belongs to the actin family.
genes like me logo Genes that share domains with ACTR10: view

Function for ACTR10 Gene

Phenotypes From GWAS Catalog for ACTR10 Gene

Gene Ontology (GO) - Molecular Function for ACTR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0106006 contributes_to microtubule cortical anchor activity IBA 21873635
genes like me logo Genes that share ontologies with ACTR10: view
genes like me logo Genes that share phenotypes with ACTR10: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ACTR10

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ACTR10 Gene

Localization for ACTR10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACTR10 Gene

Cytoplasm, cytoskeleton.

Subcellular locations from

COMPARTMENTS