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Aliases for ACTA2-AS1 Gene

Subcategory (RNA class) for ACTA2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for ACTA2-AS1 Gene

  • ACTA2 Antisense RNA 1 2 3 5
  • Uc001kfo.1 3
  • ZXF1 3

External Ids for ACTA2-AS1 Gene

Previous GeneCards Identifiers for ACTA2-AS1 Gene

  • GC10P090693

Summaries for ACTA2-AS1 Gene

GeneCards Summary for ACTA2-AS1 Gene

ACTA2-AS1 (ACTA2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with ACTA2-AS1 include Lung Cancer Susceptibility 3 and Moyamoya Disease 5.

Additional gene information for ACTA2-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACTA2-AS1 Gene

Genomics for ACTA2-AS1 Gene

GeneHancer (GH) Regulatory Elements for ACTA2-AS1 Gene

Promoters and enhancers for ACTA2-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J088931 Enhancer 1.2 Ensembl ENCODE dbSUPER 650.7 +0.2 183 2.6 PKNOX1 ZNF2 BRCA1 RAD21 RFX5 YY1 ZNF335 ZNF213 SCRT2 ZNF143 ACTA2-AS1 STAMBPL1 LIPN LIPM FAS GC10M088853
GH10J088878 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.5 -48.2 -48174 10.9 HDGF PKNOX1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF213 STAMBPL1 RPL11P3 KIF20B FAS ACTA2-AS1 RNLS ENSG00000201548 LIPJ LIPM LIPN
GH10J088988 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 11.2 +60.9 60852 8.6 HDGF PKNOX1 SMAD1 ARID4B SIN3A FEZF1 ZNF2 IRF4 YY1 ZNF213 FAS ACTA2 ENSG00000275693 FAS-AS1 ENSG00000240996 ACTA2-AS1 CH25H GC10M088853
GH10J088835 Enhancer 1.2 FANTOM5 Ensembl ENCODE 11.8 -96.8 -96848 1 RB1 ZNF2 IRF4 BRCA1 RAD21 RFX5 ZEB1 YY1 ZNF366 ZNF143 ACTA2-AS1 STAMBPL1 LIPM LIPF ANKRD22 FAS LIPN IFIT3 IFIT2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ACTA2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ACTA2-AS1 Gene

Genomic Locations for ACTA2-AS1 Gene
8,431 bases
Plus strand
7,969 bases
Plus strand

Genomic View for ACTA2-AS1 Gene

Genes around ACTA2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACTA2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACTA2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACTA2-AS1 Gene

Proteins for ACTA2-AS1 Gene

Post-translational modifications for ACTA2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ACTA2-AS1 Gene

Domains & Families for ACTA2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ACTA2-AS1 Gene

Function for ACTA2-AS1 Gene

Phenotypes From GWAS Catalog for ACTA2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ACTA2-AS1 Gene

Localization for ACTA2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ACTA2-AS1 Gene

Pathways & Interactions for ACTA2-AS1 Gene

SuperPathways for ACTA2-AS1 Gene

No Data Available

Interacting Proteins for ACTA2-AS1 Gene

Gene Ontology (GO) - Biological Process for ACTA2-AS1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ACTA2-AS1 Gene

Drugs & Compounds for ACTA2-AS1 Gene

No Compound Related Data Available

Transcripts for ACTA2-AS1 Gene

mRNA/cDNA for ACTA2-AS1 Gene

(4) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(5) RNA Central transcripts :

Unigene Clusters for ACTA2-AS1 Gene

ACTA2 antisense RNA 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACTA2-AS1 Gene

No ASD Table

Relevant External Links for ACTA2-AS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ACTA2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ACTA2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ACTA2-AS1 Gene

This gene is overexpressed in Artery - Tibial (x7.0), Artery - Coronary (x5.6), Artery - Aorta (x5.5), and Esophagus - Gastroesophageal Junction (x4.2).

SOURCE GeneReport for Unigene cluster for ACTA2-AS1 Gene:

genes like me logo Genes that share expression patterns with ACTA2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ACTA2-AS1 Gene

Orthologs for ACTA2-AS1 Gene

Evolution for ACTA2-AS1 Gene

Gene Tree for ACTA2-AS1 (if available)
Gene Tree for ACTA2-AS1 (if available)

No data available for Orthologs for ACTA2-AS1 Gene

Paralogs for ACTA2-AS1 Gene

No data available for Paralogs for ACTA2-AS1 Gene

Variants for ACTA2-AS1 Gene

Sequence variations from dbSNP and Humsavar for ACTA2-AS1 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1057518929 uncertain-significance, Arterial tortuosity, Descending aortic aneurysm, not specified 88,935,354(+) G/C non_coding_transcript_variant
rs1060503847 likely-benign, Aortic aneurysm, familial thoracic 6 88,939,529(+) G/A non_coding_transcript_variant
rs111352790 likely-benign, Aortic aneurysm, familial thoracic 6 88,935,310(+) G/A non_coding_transcript_variant
rs112208466 likely-benign, not specified, Aortic aneurysm, familial thoracic 6 88,939,508(+) G/A/C non_coding_transcript_variant
rs121434527 pathogenic, Aortic aneurysm, familial thoracic 6, Moyamoya disease 5, not provided 88,939,542(+) C/T non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ACTA2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv948130 CNV duplication 23825009
nsv831943 CNV gain 17160897
nsv831942 CNV gain 17160897
esv3624144 CNV gain 21293372
esv3624143 CNV loss 21293372
esv3624139 CNV gain 21293372

Additional Variant Information for ACTA2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ACTA2-AS1 Gene

Disorders for ACTA2-AS1 Gene

MalaCards: The human disease database

(4) MalaCards diseases for ACTA2-AS1 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
lung cancer susceptibility 3
  • lncr3
moyamoya disease 5
  • mymy5
multisystemic smooth muscle dysfunction syndrome
  • mydriasis, congenital, with patent ductus arteriosus, thoracic aortic aneurysm, and vasculopathy
aortic aneurysm, familial thoracic 6
  • aat6
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ACTA2-AS1

genes like me logo Genes that share disorders with ACTA2-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ACTA2-AS1 Gene

Publications for ACTA2-AS1 Gene

  1. Enhanced expression of long non-coding RNA ZXF1 promoted the invasion and metastasis in lung adenocarcinoma. (PMID: 24721325) Zhang L … Zhao JP (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014) 2 3 58
  2. Differential expression of genes in HepG2 cells caused by UC001kfo RNAi as shown by RNA-seq. (PMID: 28786067) Pan YF … Qin T (Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2017) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  4. Mechanical vs. disease-oriented treatment of dental caries: educational aspects. (PMID: 2808873) Thylstrup A (Journal of dental research 1989) 2 58
  5. Long non-coding RNA UC001kfo promotes hepatocellular carcinoma proliferation and metastasis by targeting α-SMA. (PMID: 28088733) Pan Y … Mu L (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017) 3

Products for ACTA2-AS1 Gene

Sources for ACTA2-AS1 Gene

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