Aliases for ACSBG1 Gene
External Ids for ACSBG1 Gene
Previous GeneCards Identifiers for ACSBG1 Gene
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACSBG1 Gene
ACSBG1 (Acyl-CoA Synthetase Bubblegum Family Member 1) is a Protein Coding gene. Diseases associated with ACSBG1 include Malignant Ovarian Surface Epithelial-Stromal Neoplasm and Ovary Epithelial Cancer. Among its related pathways are fatty acid beta-oxidation (peroxisome) and PPAR signaling pathway. Gene Ontology (GO) annotations related to this gene include long-chain fatty acid-CoA ligase activity and very long-chain fatty acid-CoA ligase activity. An important paralog of this gene is ACSBG2.
UniProtKB/Swiss-Prot Summary for ACSBG1 Gene
Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:12975357, PubMed:24269233, PubMed:10954726). Can activate diverse saturated, monosaturated and polyunsaturated fatty acids (PubMed:10954726).