Aliases for ACSBG1 Gene
External Ids for ACSBG1 Gene
Previous GeneCards Identifiers for ACSBG1 Gene
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACSBG1 Gene
ACSBG1 (Acyl-CoA Synthetase Bubblegum Family Member 1) is a Protein Coding gene. Diseases associated with ACSBG1 include Epilepsy, Idiopathic Generalized 13 and Adrenoleukodystrophy. Among its related pathways are Fatty acid biosynthesis (KEGG) and Adipocytokine signaling pathway. Gene Ontology (GO) annotations related to this gene include long-chain fatty acid-CoA ligase activity and very long-chain fatty acid-CoA ligase activity. An important paralog of this gene is ACSBG2.
UniProtKB/Swiss-Prot Summary for ACSBG1 Gene
Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:12975357, PubMed:24269233, PubMed:10954726). Can activate diverse saturated, monosaturated and polyunsaturated fatty acids (PubMed:10954726).