Aliases for ACRBP Gene
External Ids for ACRBP Gene
Previous GeneCards Identifiers for ACRBP Gene
The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACRBP Gene
ACRBP (Acrosin Binding Protein) is a Protein Coding gene. Diseases associated with ACRBP include Optic Atrophy 11.
UniProtKB/Swiss-Prot Summary for ACRBP Gene
[Acrosin-binding protein, mature form]: Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.