This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is loc... See more...

Aliases for ACPP Gene

Aliases for ACPP Gene

  • Acid Phosphatase, Prostate 2 3 5
  • Prostatic Acid Phosphatase 2 3 4
  • Thiamine Monophosphatase 3 4
  • Ecto-5'-Nucleotidase 3 4
  • EC 3.1.3.2 4 54
  • TMPase 3 4
  • 5'-NT 3 4
  • Prostatic Acid Phosphotase 3
  • 5'-Nucleotidase 4
  • EC 3.1.3.5 4
  • ACP-3 3
  • ACP3 3
  • PAP 4

External Ids for ACPP Gene

Previous GeneCards Identifiers for ACPP Gene

  • GC03P128977
  • GC03P132781
  • GC03P133317
  • GC03P133357
  • GC03P133518
  • GC03P132036
  • GC03P129415

Summaries for ACPP Gene

Entrez Gene Summary for ACPP Gene

  • This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

GeneCards Summary for ACPP Gene

ACPP (Acid Phosphatase, Prostate) is a Protein Coding gene. Diseases associated with ACPP include Prostate Cancer and Nephrogenic Adenoma Of The Urethra. Among its related pathways are Innate Immune System and ATP/ITP metabolism. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and phosphatase activity. An important paralog of this gene is ACP2.

UniProtKB/Swiss-Prot Summary for ACPP Gene

  • A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
  • Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.

Gene Wiki entry for ACPP Gene

Additional gene information for ACPP Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ACPP Gene

Genomics for ACPP Gene

GeneHancer (GH) Regulatory Elements for ACPP Gene

Promoters and enhancers for ACPP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J132316 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE CraniofacialAtlas 750.6 +0.4 410 2.8 CTCF TCF7L2 ZNF217 MNT SP7 PRDM1 PRDM10 CTBP1 ZBTB20 ZXDB ACPP ENSG00000261167 CPNE4 HSALNG0029010
GH03J132289 Enhancer 0.7 Ensembl ENCODE 16.3 -25.8 -25810 5.3 MYC MAX CREB1 CEBPB ATF7 ZFHX2 ATF2 POLR2A ACPP CPNE4 piR-56133-149
GH03J132282 Promoter/Enhancer 1 Ensembl ENCODE 4.5 -32.6 -32634 3.5 MAX PRDM1 RXRA SP1 CEBPB ZNF740 CTCF EP300 USF1 STAT1 CPNE4 ACPP RPL7P16 RF01210-273
GH03J132324 Enhancer 0.3 Ensembl 14.7 +8.4 8434 2 HLF ACPP CPNE4 HSALNG0029010
GH03J132346 Enhancer 0.7 Ensembl ENCODE 4.6 +29.6 29634 1.6 ZBTB40 CTBP1 SOX13 RFX1 FOXA2 DPF2 FOXP1 FOXA1 SOX5 ACPP HSALNG0029010
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ACPP on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ACPP gene promoter:
  • AREB6
  • Bach1
  • ER-alpha
  • Evi-1
  • FOXO1
  • FOXO1a
  • HNF-3beta
  • NF-E2
  • NF-E2 p45
  • Sox5

Genomic Locations for ACPP Gene

Genomic Locations for ACPP Gene
chr3:132,317,367-132,368,302
(GRCh38/hg38)
Size:
50,936 bases
Orientation:
Plus strand
chr3:132,036,211-132,087,146
(GRCh37/hg19)
Size:
50,936 bases
Orientation:
Plus strand

Genomic View for ACPP Gene

Genes around ACPP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACPP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACPP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACPP Gene

Proteins for ACPP Gene

  • Protein details for ACPP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P15309-PPAP_HUMAN
    Recommended name:
    Prostatic acid phosphatase
    Protein Accession:
    P15309
    Secondary Accessions:
    • D3DNC6
    • Q5FBY0
    • Q96KY0
    • Q96QK9
    • Q96QM0

    Protein attributes for ACPP Gene

    Size:
    386 amino acids
    Molecular mass:
    44566 Da
    Quaternary structure:
    • Homodimer; dimer formation is required for phosphatase activity.
    Miscellaneous:
    • Used as a diagnostic tool for staging metastatic prostatic cancer.

    Three dimensional structures from OCA and Proteopedia for ACPP Gene

    Alternative splice isoforms for ACPP Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ACPP Gene

Selected DME Specific Peptides for ACPP Gene

P15309:
  • WPQGFGQLT
  • DRTLMSA
  • DTTVSGLQMAL
  • WQPIPVHT
  • RLQGGVL

Post-translational modifications for ACPP Gene

  • N-glycosylated. High mannose content, partially sialylated and fucosylated biantennary complex. Also fucosylated with partially sialylated triantennary complex oligosaccharides.
  • Proteolytically cleaved in seminal fluid to produce several peptides. Peptide PAPf39, the most prominent, forms amyloid beta-sheet fibrils, SEVI (semen-derived enhancer of viral infection) which entrap HIV virions, attach them to target cells and enhance infection. SEVI amyloid fibrils are degraded by polyphenol epigallocatechin-3-gallate (EGCG), a constituent of green tea. Target cell attachment and enhancement of HIV infection is inhibited by surfen. Also similarly boosts XMRV (xenotropic murine leukemia virus-related virus) infection.
  • Glycosylation at Asn94, Asn220, and Asn333
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect

Antibody Products

  • Boster Bio Antibodies for ACPP

Domains & Families for ACPP Gene

Gene Families for ACPP Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for ACPP Gene

Suggested Antigen Peptide Sequences for ACPP Gene

GenScript: Design optimal peptide antigens:
  • ACPP protein (A0PJ86_HUMAN)
  • Thiamine monophosphatase (PPAP_HUMAN)
  • cDNA FLJ54158, highly similar to Prostatic acid phosphatase (EC 3.1.3.2) (Q5FBY0_HUMAN)
  • Prostatic acid phosphotase (Q6LBH1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P15309

UniProtKB/Swiss-Prot:

PPAP_HUMAN :
  • Belongs to the histidine acid phosphatase family.
Family:
  • Belongs to the histidine acid phosphatase family.
genes like me logo Genes that share domains with ACPP: view

Function for ACPP Gene

Molecular function for ACPP Gene

UniProtKB/Swiss-Prot Function:
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
UniProtKB/Swiss-Prot Function:
Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a phosphate monoester + H2O = an alcohol + phosphate; Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879, ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2; Evidence=. ;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate; Xref=Rhea:RHEA:12484, ChEBI:CHEBI:15377, ChEBI:CHEBI:18254, ChEBI:CHEBI:43474, ChEBI:CHEBI:58043; EC=3.1.3.5; Evidence=. ;.
UniProtKB/Swiss-Prot EnzymeRegulation:
Phosphatase activity inhibited by L(+)-tartrate, and by its derivative, alpha-benzylaminobenzylphosphonic acid.
GENATLAS Biochemistry:
phosphatase acid,prostate

Enzyme Numbers (IUBMB) for ACPP Gene

Phenotypes From GWAS Catalog for ACPP Gene

Gene Ontology (GO) - Molecular Function for ACPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003993 acid phosphatase activity IMP 8132635
GO:0005515 protein binding IPI 9705354
GO:0008253 5'-nucleotidase activity IEA,IDA 18940592
GO:0016787 hydrolase activity IEA --
GO:0016791 phosphatase activity IMP 18940592
genes like me logo Genes that share ontologies with ACPP: view
genes like me logo Genes that share phenotypes with ACPP: view

Animal Models for ACPP Gene

MGI Knock Outs for ACPP:
  • Acpp Acpp<tm1Pivi>

Animal Model Products

  • Taconic Biosciences Mouse Models for ACPP

CRISPR Products

Clone Products

  • Addgene plasmids for ACPP

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ACPP Gene

Localization for ACPP Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACPP Gene

Isoform 1: Secreted.
Isoform 2: Cell membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319). {ECO:0000269 PubMed:17638863, ECO:0000269 PubMed:17897319}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ACPP gene
Compartment Confidence
plasma membrane 5
extracellular 5
lysosome 4
cytoskeleton 1
mitochondrion 1
cytosol 1
golgi apparatus 1
peroxisome 0

Gene Ontology (GO) - Cellular Components for ACPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005615 extracellular space IMP 22389722
GO:0005634 nucleus HDA 21630459
GO:0005764 lysosome IEA --
GO:0005765 lysosomal membrane IEA,HDA 17897319
genes like me logo Genes that share ontologies with ACPP: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ACPP Gene

Pathways & Interactions for ACPP Gene

PathCards logo

SuperPathways for ACPP Gene

genes like me logo Genes that share pathways with ACPP: view

Pathways by source for ACPP Gene

3 Reactome pathways for ACPP Gene
1 GeneGo (Thomson Reuters) pathway for ACPP Gene

Gene Ontology (GO) - Biological Process for ACPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006144 purine nucleobase metabolic process IEA --
GO:0006772 thiamine metabolic process IEA,ISS --
GO:0009117 nucleotide metabolic process IEA --
GO:0016311 dephosphorylation IMP 8132635
GO:0043312 neutrophil degranulation TAS --
genes like me logo Genes that share ontologies with ACPP: view

No data available for SIGNOR curated interactions for ACPP Gene

Drugs & Compounds for ACPP Gene

(53) Drugs for ACPP Gene - From: DrugBank, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Sipuleucel-T Approved, Investigational Pharma Target, other 0
Flavin Mononucleotide Approved, Investigational Pharma 10
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
Riboflavin Approved, Investigational, Vet_approved Nutra 214

(27) Additional Compounds for ACPP Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Phosphate
  • [po(OH)3]
  • Acide phosphorique
  • Acidum phosphoricum
  • H3PO4
  • Orthophosphoric acid
14066-19-4, 14265-44-2
genes like me logo Genes that share compounds with ACPP: view

Transcripts for ACPP Gene

CRISPR Products

Clone Products

  • Addgene plasmids for ACPP

Alternative Splicing Database (ASD) splice patterns (SP) for ACPP Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11
SP1: - - - -
SP2: - -
SP3: - - -
SP4:
SP5: - - -
SP6:

Relevant External Links for ACPP Gene

GeneLoc Exon Structure for
ACPP
ECgene alternative splicing isoforms for
ACPP

Expression for ACPP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ACPP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ACPP Gene

This gene is overexpressed in Prostate (x47.6).

Protein differential expression in normal tissues from HIPED for ACPP Gene

This gene is overexpressed in Urine (28.4), Prostate (20.6), and Seminal vesicle (10.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ACPP Gene



NURSA nuclear receptor signaling pathways regulating expression of ACPP Gene:

ACPP

SOURCE GeneReport for Unigene cluster for ACPP Gene:

Hs.433060

mRNA Expression by UniProt/SwissProt for ACPP Gene:

P15309-PPAP_HUMAN
Tissue specificity: Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer.

Evidence on tissue expression from TISSUES for ACPP Gene

  • Kidney(2.2)
  • Blood(2.1)
genes like me logo Genes that share expression patterns with ACPP: view

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ACPP Gene

Orthologs for ACPP Gene

This gene was present in the common ancestor of animals.

Orthologs for ACPP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ACPP 33 32
  • 99.44 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ACPP 33 32
  • 85.07 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ACPP 33 32
  • 84.61 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Acpp 17 33 32
  • 82.86 (n)
rat
(Rattus norvegicus)
Mammalia Acpp 32
  • 82 (n)
oppossum
(Monodelphis domestica)
Mammalia ACPP 33
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ACPP 33
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves ACPP 33 32
  • 61.21 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ACPP 33
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia acpp 32
  • 58.03 (n)
fruit fly
(Drosophila melanogaster)
Insecta Acph-1 33 34
  • 32 (a)
ManyToMany
CG9449 33 34
  • 30 (a)
ManyToMany
CG9451 33 34
  • 29 (a)
ManyToMany
CG9452 33 34
  • 27 (a)
ManyToMany
CG6656 33 34
  • 26 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea pho-6 32
  • 43.24 (n)
T13B5.3 34
  • 32 (a)
F52E1.8 34
  • 32 (a)
T21B6.2 34
  • 31 (a)
pho-14 33
  • 30 (a)
ManyToMany
R13H4.3 34
  • 29 (a)
pho-5 33
  • 28 (a)
ManyToMany
pho-12 33
  • 25 (a)
ManyToMany
pho-10 33
  • 25 (a)
ManyToMany
pho-1 33 34
  • 24 (a)
ManyToMany
F26C11.1 33
  • 24 (a)
ManyToMany
C27A2.12 33
  • 23 (a)
ManyToMany
pho-11 33
  • 23 (a)
ManyToMany
pho-13 33
  • 22 (a)
ManyToMany
pho-4 33
  • 22 (a)
ManyToMany
acp-1 33
  • 21 (a)
ManyToMany
acp-5 33
  • 21 (a)
ManyToMany
acp-3 33
  • 21 (a)
ManyToMany
acp-2 33
  • 20 (a)
ManyToMany
acp-4 33
  • 18 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 33
  • 35 (a)
OneToMany
Cin.11668 32
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.11668 32
Species where no ortholog for ACPP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ACPP Gene

ENSEMBL:
Gene Tree for ACPP (if available)
TreeFam:
Gene Tree for ACPP (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ACPP: view image

Paralogs for ACPP Gene

Paralogs for ACPP Gene

(2) SIMAP similar genes for ACPP Gene using alignment to 5 proteins:

  • PPAP_HUMAN
  • A0PJ86_HUMAN
  • E9PFE6_HUMAN
  • H0Y8T3_HUMAN
  • Q6LBH1_HUMAN
genes like me logo Genes that share paralogs with ACPP: view

Variants for ACPP Gene

Sequence variations from dbSNP and Humsavar for ACPP Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs864309497 uncertain-significance, Acute megakaryoblastic leukemia, Mediastinal germ cell tumor 132,349,986(+) TCATCAT/TCAT coding_sequence_variant, inframe_deletion
rs1000006397 -- 132,348,241(+) G/T intron_variant
rs1000084793 -- 132,347,190(+) C/T intron_variant
rs1000124506 -- 132,361,432(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000144114 -- 132,357,053(+) C/T 3_prime_UTR_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ACPP Gene

Variant ID Type Subtype PubMed ID
esv2762346 CNV loss 21179565
esv3597825 CNV loss 21293372
nsv478509 CNV novel sequence insertion 20440878
nsv508245 CNV deletion 20534489
nsv829728 CNV gain 17160897

Variation tolerance for ACPP Gene

Residual Variation Intolerance Score: 21.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.68; 32.12% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ACPP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ACPP

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACPP Gene

Disorders for ACPP Gene

MalaCards: The human disease database

(6) MalaCards diseases for ACPP Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
prostate cancer
  • prostate cancer, somatic
nephrogenic adenoma of the urethra
  • nephrogenic adenoma of urethra
phosphatase, acid, of tissues
  • lysosomal acid phosphatase
prostate disease
  • prostate diseases
atypical choroid plexus papilloma
  • atypical papilloma of choroid plexus
- elite association - COSMIC cancer census association via MalaCards
Search ACPP in MalaCards View complete list of genes associated with diseases

Additional Disease Information for ACPP

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ACPP: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ACPP Gene

Publications for ACPP Gene

  1. Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase. (PMID: 9804805) LaCount MW … Lebioda L (The Journal of biological chemistry 1998) 3 4 23 56
  2. Structure of human prostatic acid phosphatase gene. (PMID: 1375464) Sharief FS … Li SS (Biochemical and biophysical research communications 1992) 2 3 4 56
  3. Molecular cloning and sequence analysis of cDNA encoding human prostatic acid phosphatase. (PMID: 2842184) Vihko P … Huhtala ML (FEBS letters 1988) 2 3 4 56
  4. Prostatic acid phosphatase expression in human tissues. (PMID: 21487525) Graddis TJ … Trager JB (International journal of clinical and experimental pathology 2011) 3 4 56
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 43 56

Products for ACPP Gene

  • Addgene plasmids for ACPP

Sources for ACPP Gene