ACP3 Gene (Protein Coding)

Acid Phosphatase 3

GC03P132319
GIFtS:
36
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is loc... See more...

Aliases for ACP3 Gene

Aliases for ACP3 Gene

  • Acid Phosphatase 3 2 3
  • Prostatic Acid Phosphatase 2 3 4
  • Acid Phosphatase, Prostate 2 3 5
  • Thiamine Monophosphatase 3 4
  • Ecto-5'-Nucleotidase 3 4
  • EC 3.1.3.2 4 52
  • TMPase 3 4
  • 5'-NT 3 4
  • ACPP 3 5
  • Prostatic Acid Phosphotase 3
  • 5'-Nucleotidase 4
  • EC 3.1.3.5 4
  • TM-PAP 3
  • ACP-3 3
  • PAP 4

External Ids for ACP3 Gene

Previous HGNC Symbols for ACP3 Gene

  • ACPP

Summaries for ACP3 Gene

Entrez Gene Summary for ACP3 Gene

  • This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

GeneCards Summary for ACP3 Gene

ACP3 (Acid Phosphatase 3) is a Protein Coding gene. Diseases associated with ACP3 include Prostatitis and Prostatic Hyperplasia, Benign. Among its related pathways are Innate Immune System and ATP/ITP metabolism. An important paralog of this gene is ACP2.

UniProtKB/Swiss-Prot Summary for ACP3 Gene

  • A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
  • [Isoform 2]: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.

Gene Wiki entry for ACP3 Gene

Additional gene information for ACP3 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ACP3 Gene

Genomics for ACP3 Gene

GeneHancer (GH) Regulatory Elements for ACP3 Gene

Promoters and enhancers for ACP3 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH03J132316 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +0.4 410 2.8 ZNF217 POLR2A TRIM28 RFX1 CUX1 CTBP1 ZNF341 OSR2 SIN3A ESRRA ACP3 ENSG00000261167 CPNE4 HSALNG0029010
GH03J132289 Enhancer 0.7 Ensembl ENCODE 16.3 -25.8 -25810 5.3 ATF2 CREB1 CEBPB SPI1 ZFHX2 POLR2A JUND MYC MAX JUN ACP3 CPNE4 piR-56133-149
GH03J132282 Promoter/Enhancer 1 Ensembl ENCODE 4.5 -32.6 -32634 3.5 CTCF USF1 EP300 HINFP CEBPB GTF2A2 SPI1 STAT1 GATA2 USF2 CPNE4 ACP3 RPL7P16 RF01210-273
GH03J132324 Enhancer 0.3 Ensembl 14.7 +8.4 8434 2 HLF ACP3 CPNE4 HSALNG0029010
GH03J132346 Enhancer 0.8 Ensembl ENCODE 4.7 +29.6 29634 1.6 TCF12 RFX1 CTBP1 FOXA2 SPI1 ESR1 FOXP1 FOXA1 DPF2 ZBTB40 ACP3 HSALNG0029010
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ACP3 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ACP3

Genomic Locations for ACP3 Gene

Genomic Locations for ACP3 Gene
chr3:132,317,367-132,368,302
(GRCh38/hg38)
Size:
50,936 bases
Orientation:
Plus strand
chr3:132,036,211-132,087,146
(GRCh37/hg19)
Size:
50,936 bases
Orientation:
Plus strand

Genomic View for ACP3 Gene

Genes around ACP3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACP3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACP3 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for ACP3 Gene

Proteins for ACP3 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for ACP3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P15309-PPAP_HUMAN
    Recommended name:
    Prostatic acid phosphatase
    Protein Accession:
    P15309
    Secondary Accessions:
    • D3DNC6
    • Q5FBY0
    • Q96KY0
    • Q96QK9
    • Q96QM0

    Protein attributes for ACP3 Gene

    Size:
    386 amino acids
    Molecular mass:
    44566 Da
    Quaternary structure:
    • Homodimer; dimer formation is required for phosphatase activity.
    Miscellaneous:
    • Used as a diagnostic tool for staging metastatic prostatic cancer.

    Three dimensional structures from OCA and Proteopedia for ACP3 Gene

    Alternative splice isoforms for ACP3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ACP3 Gene

Selected DME Specific Peptides for ACP3 Gene

P15309:
  • WPQGFGQLT
  • DRTLMSA
  • DTTVSGLQMAL
  • WQPIPVHT
  • RLQGGVL

Post-translational modifications for ACP3 Gene

  • N-glycosylated. High mannose content, partially sialylated and fucosylated biantennary complex. Also fucosylated with partially sialylated triantennary complex oligosaccharides.
  • Proteolytically cleaved in seminal fluid to produce several peptides. Peptide PAPf39, the most prominent, forms amyloid beta-sheet fibrils, SEVI (semen-derived enhancer of viral infection) which entrap HIV virions, attach them to target cells and enhance infection. SEVI amyloid fibrils are degraded by polyphenol epigallocatechin-3-gallate (EGCG), a constituent of green tea. Target cell attachment and enhancement of HIV infection is inhibited by surfen. Also similarly boosts XMRV (xenotropic murine leukemia virus-related virus) infection.
  • Glycosylation at Asn94, Asn220, and Asn333
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect

Other Protein References for ACP3 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Boster Bio Antibodies for ACP3

Domains & Families for ACP3 Gene

Gene Families for ACP3 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for ACP3 Gene

Blocks:
  • Histidine acid phosphatase
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ACP3 Gene

GenScript: Design optimal peptide antigens:
  • ACPP protein (A0PJ86_HUMAN)
  • Thiamine monophosphatase (PPAP_HUMAN)
  • cDNA FLJ54158, highly similar to Prostatic acid phosphatase (EC 3.1.3.2) (Q5FBY0_HUMAN)
  • Prostatic acid phosphotase (Q6LBH1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P15309

UniProtKB/Swiss-Prot:

PPAP_HUMAN :
  • Belongs to the histidine acid phosphatase family.
Family:
  • Belongs to the histidine acid phosphatase family.
genes like me logo Genes that share domains with ACP3: view

Function for ACP3 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for ACP3 Gene

UniProtKB/Swiss-Prot Function:
A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
UniProtKB/Swiss-Prot Function:
[Isoform 2]: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a phosphate monoester + H2O = an alcohol + phosphate; Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879, ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2; Evidence=. ;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate; Xref=Rhea:RHEA:12484, ChEBI:CHEBI:15377, ChEBI:CHEBI:18254, ChEBI:CHEBI:43474, ChEBI:CHEBI:58043; EC=3.1.3.5; Evidence=. ;.
UniProtKB/Swiss-Prot EnzymeRegulation:
Phosphatase activity inhibited by L(+)-tartrate, and by its derivative, alpha-benzylaminobenzylphosphonic acid.

Enzyme Numbers (IUBMB) for ACP3 Gene

Phenotypes From GWAS Catalog for ACP3 Gene

Gene Ontology (GO) - Molecular Function for ACP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003993 acid phosphatase activity IMP 8132635
GO:0005515 protein binding IPI 9705354
GO:0008253 5'-nucleotidase activity IDA,IEA 18940592
GO:0016787 hydrolase activity IEA --
GO:0016791 phosphatase activity IMP 18940592
genes like me logo Genes that share ontologies with ACP3: view
genes like me logo Genes that share phenotypes with ACP3: view

Animal Models for ACP3 Gene

MGI Knock Outs for ACP3:
  • Acpp Acpp<tm1Pivi>

Animal Model Products

  • Taconic Biosciences Mouse Models for ACP3

CRISPR Products

miRNA for ACP3 Gene

miRTarBase miRNAs that target ACP3

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ACP3 Gene

Localization for ACP3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACP3 Gene

[Isoform 1]: Secreted.
[Isoform 2]: Cell membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319). {ECO:0000269 PubMed:17638863, ECO:0000269 PubMed:17897319}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ACP3 gene
Compartment Confidence
plasma membrane 5
extracellular 5
lysosome 4
cytoskeleton 2
mitochondrion 2
nucleus 2
cytosol 2
golgi apparatus 2
endoplasmic reticulum 1
endosome 1
peroxisome 0

Gene Ontology (GO) - Cellular Components for ACP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005615 extracellular space IMP 22389722
GO:0005634 nucleus HDA 21630459
GO:0005764 lysosome IEA --
GO:0005765 lysosomal membrane IEA,HDA 17897319
genes like me logo Genes that share ontologies with ACP3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ACP3 Gene

Pathways & Interactions for ACP3 Gene

PathCards logo

SuperPathways for ACP3 Gene

SuperPathway Contained pathways
1 Innate Immune System
Immune System
.61
Innate Immune System
.61
Neutrophil degranulation
.38
2 ATP/ITP metabolism
ATP/ITP metabolism
-
genes like me logo Genes that share pathways with ACP3: view

Pathways by source for ACP3 Gene

3 Reactome pathways for ACP3 Gene
1 GeneGo (Thomson Reuters) pathway for ACP3 Gene
  • ATP/ITP metabolism

Gene Ontology (GO) - Biological Process for ACP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006144 purine nucleobase metabolic process IEA --
GO:0006772 thiamine metabolic process IEA,ISS --
GO:0009117 nucleotide metabolic process IEA --
GO:0016311 dephosphorylation IMP 8132635
GO:0043312 neutrophil degranulation TAS --
genes like me logo Genes that share ontologies with ACP3: view

No data available for SIGNOR curated interactions for ACP3 Gene

Drugs & Compounds for ACP3 Gene

Products:

  1. Drug

(53) Drugs for ACP3 Gene - From: DrugBank, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Sipuleucel-T Approved, Investigational Pharma Target, other 0
Flavin Mononucleotide Approved, Investigational Pharma 11
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
Riboflavin Approved, Investigational, Vet_approved Nutra 220

(27) Additional Compounds for ACP3 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Phosphate
  • [po(OH)3]
  • Acide phosphorique
  • Acidum phosphoricum
  • H3PO4
  • Orthophosphoric acid
 14066-19-4, 14265-44-2
genes like me logo Genes that share compounds with ACP3: view

Transcripts for ACP3 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for ACP3 Gene

3 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACP3 Gene

No ASD Table

Relevant External Links for ACP3 Gene

GeneLoc Exon Structure for
ACP3

Expression for ACP3 Gene

Products:

  1. Primer

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ACP3

SOURCE GeneReport for Unigene cluster for ACP3 Gene:

Hs.433060

mRNA Expression by UniProt/SwissProt for ACP3 Gene:

P15309-PPAP_HUMAN
Tissue specificity: Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer.

Evidence on tissue expression from TISSUES for ACP3 Gene

  • Kidney(2.2)
  • Blood(2.1)
genes like me logo Genes that share expression patterns with ACP3: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ACP3 Gene

Orthologs for ACP3 Gene

This gene was present in the common ancestor of animals.

Orthologs for ACP3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ACPP 31 30
  • 99.44 (n)
 OneToOne
cow
(Bos Taurus)
 Mammalia ACPP 31 30
  • 85.07 (n)
 OneToOne
dog
(Canis familiaris)
 Mammalia ACPP 31 30
  • 84.61 (n)
 OneToOne
mouse
(Mus musculus)
 Mammalia Acpp 17 31 30
  • 82.86 (n)
rat
(Rattus norvegicus)
 Mammalia Acpp 30
  • 82 (n)
oppossum
(Monodelphis domestica)
 Mammalia ACPP 31
  • 67 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia ACPP 31
  • 67 (a)
 OneToOne
chicken
(Gallus gallus)
 Aves ACPP 31 30
  • 61.21 (n)
 OneToOne
lizard
(Anolis carolinensis)
 Reptilia ACPP 31
  • 51 (a)
 OneToOne
tropical clawed frog
(Silurana tropicalis)
 Amphibia acpp 30
  • 58.03 (n)
fruit fly
(Drosophila melanogaster)
 Insecta Acph-1 31
  • 32 (a)
 ManyToMany
CG9449 31
  • 30 (a)
 ManyToMany
CG9451 31
  • 29 (a)
 ManyToMany
CG9452 31
  • 27 (a)
 ManyToMany
CG6656 31
  • 26 (a)
 ManyToMany
worm
(Caenorhabditis elegans)
 Secernentea pho-6 30
  • 43.24 (n)
pho-14 31
  • 30 (a)
 ManyToMany
pho-5 31
  • 28 (a)
 ManyToMany
pho-12 31
  • 25 (a)
 ManyToMany
pho-10 31
  • 25 (a)
 ManyToMany
pho-1 31
  • 24 (a)
 ManyToMany
F26C11.1 31
  • 24 (a)
 ManyToMany
C27A2.12 31
  • 23 (a)
 ManyToMany
pho-11 31
  • 23 (a)
 ManyToMany
pho-13 31
  • 22 (a)
 ManyToMany
pho-4 31
  • 22 (a)
 ManyToMany
acp-1 31
  • 21 (a)
 ManyToMany
acp-5 31
  • 21 (a)
 ManyToMany
acp-3 31
  • 21 (a)
 ManyToMany
acp-2 31
  • 20 (a)
 ManyToMany
acp-4 31
  • 18 (a)
 ManyToMany
sea squirt
(Ciona savignyi)
 Ascidiacea -- 31
  • 35 (a)
 OneToMany
Cin.11668 30
sea squirt
(Ciona intestinalis)
 Ascidiacea Cin.11668 30
Species where no ortholog for ACP3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ACP3 Gene

ENSEMBL:
Gene Tree for ACP3 (if available)
TreeFam:
Gene Tree for ACP3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ACP3: view image

Paralogs for ACP3 Gene

Paralogs for ACP3 Gene

genes like me logo Genes that share paralogs with ACP3: view

Variants for ACP3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ACP3 Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
714205 Benign: not provided 132,352,758(+) T/G MISSENSE_VARIANT
714983 Benign: not provided 132,332,272(+) T/C SYNONYMOUS_VARIANT
729506 Likely Benign: not provided 132,337,518(+) A/G SYNONYMOUS_VARIANT,INTRON_VARIANT
740129 Likely Benign: not provided 132,328,263(+) T/C INTRON_VARIANT
rs864309497 Uncertain Significance: Acute megakaryoblastic leukemia; Mediastinal germ cell tumor 132,349,985(+) CTCA/C INFRAME_DELETION

Additional dbSNP identifiers (rs#s) for ACP3 Gene

Structural Variations from Database of Genomic Variants (DGV) for ACP3 Gene

Variant ID Type Subtype PubMed ID
esv2762346 CNV loss 21179565
esv3597825 CNV loss 21293372
nsv478509 CNV novel sequence insertion 20440878
nsv508245 CNV deletion 20534489
nsv829728 CNV gain 17160897

Variation tolerance for ACP3 Gene

Residual Variation Intolerance Score: 21.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.68; 32.12% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ACP3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ACP3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACP3 Gene

Disorders for ACP3 Gene

MalaCards: The human disease database

(17) MalaCards diseases for ACP3 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
prostatitis
prostatic hyperplasia, benign
  • bph
clear cell adenocarcinoma
  • malignant mesonephroma
phosphatase, acid, of tissues
  • lysosomal acid phosphatase
prostate cancer
  • prostate cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search ACP3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for ACP3

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ACP3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ACP3 Gene

Publications for ACP3 Gene

  1. Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase. (PMID: 9804805) LaCount MW … Lebioda L (The Journal of biological chemistry 1998) 3 4 23 54
  2. Structure of human prostatic acid phosphatase gene. (PMID: 1375464) Sharief FS … Li SS (Biochemical and biophysical research communications 1992) 2 3 4 54
  3. Molecular cloning and sequence analysis of cDNA encoding human prostatic acid phosphatase. (PMID: 2842184) Vihko P … Huhtala ML (FEBS letters 1988) 2 3 4 54
  4. Prostatic acid phosphatase expression in human tissues. (PMID: 21487525) Graddis TJ … Trager JB (International journal of clinical and experimental pathology 2011) 3 4 54
  5. Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth. (PMID: 20498373) Chuang TD … Lin MF (The Journal of biological chemistry 2010) 3 4 54

ExternalLinks

View latest publications for ACP3 gene in Mastermind

Products for ACP3 Gene

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