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ACP2 Gene(Protein Coding)

Acid Phosphatase 2, Lysosomal

GCID:
GC11M054245
GIFtS:
53
Genes Participants
UDN Logo

Aliases for ACP2 Gene

Aliases for ACP2 Gene

  • Acid Phosphatase 2, Lysosomal 2 3 5
  • Lysosomal Acid Phosphatase 2 3
  • EC 3.1.3.2 4 56
  • LAP 3 4

External Ids for ACP2 Gene

Previous GeneCards Identifiers for ACP2 Gene

  • GC11M049200
  • GC11M048138
  • GC11M047292
  • GC11M047225
  • GC11M047218
  • GC11M046959
  • GC11M047260
  • GC11M047358
  • GC11M047942
  • GC11M050794
  • GC11M051589
  • GC11M052251
  • GC11M052911
  • GC11M053579

Summaries for ACP2 Gene

Entrez Gene Summary for ACP2 Gene

  • The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]

GeneCards Summary for ACP2 Gene

ACP2 (Acid Phosphatase 2, Lysosomal) is a Protein Coding gene. Diseases associated with ACP2 include Acid Phosphatase Deficiency and Phosphatase, Acid, Of Tissues. Among its related pathways are Riboflavin metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include acid phosphatase activity. An important paralog of this gene is ACPP.

Gene Wiki entry for ACP2 Gene

Additional gene information for ACP2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACP2 Gene

Genomics for ACP2 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for ACP2 Gene

Promoters and enhancers for ACP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH11I047247 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 567.8 +0.1 121 2.2 ZFP64 FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 MEF2D ACP2 NR1H3 DDB2 NUP160 ENSG00000270060 FNBP4 RPS10P19 PACSIN3 ZNF408 ENSG00000200090
GH11I047267 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 27.5 -21.4 -21438 5.4 HDGF PKNOX1 CLOCK FOXA2 ARNT ZFP64 ARID4B SIN3A FEZF1 YY1 MADD LOC101928943 FNBP4 NUP160 ENSG00000270060 ENSG00000200090 DDB2 ACP2 RPS10P19 PACSIN3
GH11I047256 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 16.3 -9.9 -9907 3.9 MLX ARID4B DMAP1 BRCA1 ZNF48 YY1 ZNF121 GLIS2 ELK1 ARID2 NR1H3 PACSIN3 ACP2 ARFGAP2 MADD C1QTNF4
GH11I047252 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 16.3 -5.7 -5719 4.1 ELF3 MLX ARID4B DMAP1 RAD21 THRB RARA YY1 ZNF121 ZNF366 ACP2 ENSG00000256897 DDB2 PACSIN3 ARFGAP2 MADD MYBPC3 SPI1 CELF1 NR1H3
GH11I047263 Enhancer 1.3 Ensembl ENCODE dbSUPER 16.2 -16.3 -16272 2.5 HDAC1 HDGF PKNOX1 ATF1 ARNT NFRKB TCF12 ZNF766 ELK1 FOS ACP2 PACSIN3 MADD NR1H3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ACP2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ACP2 gene promoter:

Genomic Locations for ACP2 Gene

Genomic Locations for ACP2 Gene
chr11:47,239,302-47,248,906
(GRCh38/hg38)
Size:
9,605 bases
Orientation:
Minus strand
chr11:47,260,853-47,270,457
(GRCh37/hg19)

Genomic View for ACP2 Gene

Genes around ACP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACP2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for ACP2 Gene

Proteins for ACP2 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for ACP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P11117-PPAL_HUMAN
    Recommended name:
    Lysosomal acid phosphatase
    Protein Accession:
    P11117
    Secondary Accessions:
    • E9PCI1
    • Q561W5
    • Q9BTU7

    Protein attributes for ACP2 Gene

    Size:
    423 amino acids
    Molecular mass:
    48344 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ACP2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ACP2 Gene

Protein Expression for ACP2 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Selected DME Specific Peptides for ACP2 Gene

P11117:
  • WPQGFGQLT
  • DRTLMSA
  • EQLQNETR
  • VYDTLFC
  • NAQFLDMVANETGL
  • WQPIPVHT
  • RLQGGVL
  • PEYQNES
  • GWSRAALLQL
  • YRHGDRSPV
  • ANLAGLFP
  • PKLLVYSAHDTTLVALQMAL
  • EDRLLKFPLGPCPR
  • YPKDPYQEE
  • GNFSVEMYFRN
  • ADTEVIVALAVCGSILFLLIVLLLT
  • LPPWASPQT
  • RSTDFDRTL
  • VYNGEQAPYASCH

Post-translational modifications for ACP2 Gene

  • N-glycosylated. The intermediates formed during enzymatic deglycosylation suggest that all eight predicted N-glycosylation sites are used.
  • The membrane-bound form is converted to the soluble form by sequential proteolytic processing. First, the C-terminal cytoplasmic tail is removed. Cleavage by a lysosomal protease releases the soluble form in the lysosome lumen.
  • Glycosylation at posLast=9292, Asn133, posLast=167167, posLast=177177, posLast=191191, Asn267, Asn322, and Asn331
  • Modification sites at PhosphoSitePlus

Other Protein References for ACP2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for ACP2 Gene

Gene Families for ACP2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for ACP2 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ACP2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P11117

UniProtKB/Swiss-Prot:

PPAL_HUMAN :
  • Belongs to the histidine acid phosphatase family.
Family:
  • Belongs to the histidine acid phosphatase family.
genes like me logo Genes that share domains with ACP2: view

Function for ACP2 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Molecular function for ACP2 Gene

GENATLAS Biochemistry:
phosphatase acid,lysosomal
UniProtKB/Swiss-Prot CatalyticActivity:
A phosphate monoester + H(2)O = an alcohol + phosphate.

Enzyme Numbers (IUBMB) for ACP2 Gene

Phenotypes From GWAS Catalog for ACP2 Gene

Gene Ontology (GO) - Molecular Function for ACP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003993 acid phosphatase activity IEA,TAS --
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ACP2: view
genes like me logo Genes that share phenotypes with ACP2: view

Human Phenotype Ontology for ACP2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for ACP2 Gene

MGI Knock Outs for ACP2:

Animal Model Products

miRNA for ACP2 Gene

miRTarBase miRNAs that target ACP2

Clone Products

No data available for Transcription Factor Targets and HOMER Transcription for ACP2 Gene

Localization for ACP2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACP2 Gene

Lysosome membrane; Single-pass membrane protein; Lumenal side. Lysosome lumen. Note=The soluble form arises by proteolytic processing of the membrane-bound form. {ECO:0000269 PubMed:2684640, ECO:0000269 PubMed:3056714}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ACP2 gene
Compartment Confidence
extracellular 5
lysosome 5
plasma membrane 2
mitochondrion 2
golgi apparatus 2
nucleus 1
endoplasmic reticulum 1
endosome 1

Gene Ontology (GO) - Cellular Components for ACP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005764 lysosome IDA 3160696
GO:0005765 lysosomal membrane IEA --
GO:0016020 membrane IEA,HDA 19946888
GO:0016021 integral component of membrane IEA --
GO:0043202 lysosomal lumen IEA --
genes like me logo Genes that share ontologies with ACP2: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ACP2 Gene

Pathways & Interactions for ACP2 Gene

genes like me logo Genes that share pathways with ACP2: view

Pathways by source for ACP2 Gene

3 KEGG pathways for ACP2 Gene
1 GeneGo (Thomson Reuters) pathway for ACP2 Gene

Gene Ontology (GO) - Biological Process for ACP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001501 skeletal system development IEA --
GO:0007040 lysosome organization IEA --
GO:0016311 dephosphorylation IEA --
genes like me logo Genes that share ontologies with ACP2: view

No data available for SIGNOR curated interactions for ACP2 Gene

Drugs & Compounds for ACP2 Gene

Products:

  1. Drug

(10) Drugs for ACP2 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Isopropyl alcohol Approved, Investigational Pharma 0
Phosphoric acid Approved Pharma 0
Propyl alcohol Approved, Experimental Pharma 0
Water Approved Pharma 0
Riboflavin Approved, Investigational, Vet_approved Nutra 188

(4) Additional Compounds for ACP2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
1-Hexanol
  • 1-Hexanol
  • 1-Hexyl alcohol
  • 1-Hydroxyhexane
  • Alcohol C-6
  • Alcohol(C6)
 111-27-3
1-Pentanol
  • 1-Pentanol
  • 1-Pentol
  • 1-Pentyl alcohol
  • Alcool amylique
  • Alcool amylique (french)
 71-41-0
Isobutanol
  • 1-Hydroxymethylpropane
  • 2-Methyl propanol
  • 2-Methyl-1-propanol
  • 2-Methyl-1-propanyl alcohol
  • 2-Methylpropan-1-ol
 78-83-1
Phosphate
  • NFB Orthophosphate
  • O-Phosphoric acid
  • Ortho-phosphate
  • Orthophosphate (PO43-)
  • Orthophosphate(3-)
 14265-44-2
genes like me logo Genes that share compounds with ACP2: view

Transcripts for ACP2 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for ACP2 Gene

(7) REFSEQ mRNAs :
(15) Additional mRNA sequences :
(293) Selected AceView cDNA sequences:
(14) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ACP2 Gene

Acid phosphatase 2, lysosomal:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACP2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1: - - - -
SP2: - - -
SP3:
SP4: -
SP5:
SP6:

Relevant External Links for ACP2 Gene

GeneLoc Exon Structure for
ACP2
ECgene alternative splicing isoforms for
ACP2

Expression for ACP2 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ACP2 Gene

mRNA expression in normal human tissues for ACP2 Gene
mRNA expression by BioGPS for ACP2 GenemRNA expression by GTEx for ACP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ACP2 Gene

This gene is overexpressed in Urine (23.7) and Nasal epithelium (13.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ACP2 Gene



NURSA nuclear receptor signaling pathways regulating expression of ACP2 Gene:

ACP2

SOURCE GeneReport for Unigene cluster for ACP2 Gene:

Hs.532492

Evidence on tissue expression from TISSUES for ACP2 Gene

  • Nervous system(5)
  • Kidney(4.8)
  • Liver(4.7)
  • Blood(4.6)
  • Lung(2.9)
  • Intestine(2.6)
  • Spleen(2.4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for ACP2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • nervous
  • skeletal muscle
Regions:
Head and neck:
  • brain
  • head
Thorax:
  • esophagus
Abdomen:
  • stomach
General:
  • blood
  • blood vessel
  • coagulation system
  • peripheral nerve
  • peripheral nervous system
genes like me logo Genes that share expression patterns with ACP2: view

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ACP2 Gene

Orthologs for ACP2 Gene

This gene was present in the common ancestor of animals.

Orthologs for ACP2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ACP2 33 34
  • 99.61 (n)
dog
(Canis familiaris)
 Mammalia ACP2 33 34
  • 91.65 (n)
cow
(Bos Taurus)
 Mammalia ACP2 33 34
  • 88.97 (n)
mouse
(Mus musculus)
 Mammalia Acp2 33 16 34
  • 88.1 (n)
rat
(Rattus norvegicus)
 Mammalia Acp2 33
  • 87.71 (n)
oppossum
(Monodelphis domestica)
 Mammalia ACP2 34
  • 83 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia ACP2 34
  • 74 (a)
 OneToOne
chicken
(Gallus gallus)
 Aves ACP2 33 34
  • 69.42 (n)
lizard
(Anolis carolinensis)
 Reptilia ACP2 34
  • 66 (a)
 OneToOne
tropical clawed frog
(Silurana tropicalis)
 Amphibia acp2 33
  • 62.29 (n)
Str.3282 33
zebrafish
(Danio rerio)
 Actinopterygii acp2 33
  • 60.1 (n)
ACP2 34
  • 53 (a)
 OneToOne
Dr.25243 33
fruit fly
(Drosophila melanogaster)
 Insecta Acph-1 35 33 34
  • 49.21 (n)
CG9449 35 34
  • 34 (a)
CG9451 35 34
  • 34 (a)
CG9452 35 34
  • 32 (a)
CG6656 35 34
  • 31 (a)
African malaria mosquito
(Anopheles gambiae)
 Insecta AgaP_AGAP002387 33
  • 48.71 (n)
worm
(Caenorhabditis elegans)
 Secernentea pho-5 33 34
  • 44.01 (n)
R13H4.3 35
  • 33 (a)
T13B5.3 35
  • 33 (a)
F52E1.8 35
  • 31 (a)
T21B6.2 35
  • 31 (a)
B0361.7 35
  • 30 (a)
pho-14 34
  • 28 (a)
 ManyToMany
pho-12 34
  • 26 (a)
 ManyToMany
acp-5 34
  • 24 (a)
 ManyToMany
pho-1 34
  • 24 (a)
 ManyToMany
pho-10 34
  • 24 (a)
 ManyToMany
pho-4 34
  • 24 (a)
 ManyToMany
F26C11.1 34
  • 23 (a)
 ManyToMany
pho-13 34
  • 23 (a)
 ManyToMany
C27A2.12 34
  • 22 (a)
 ManyToMany
pho-11 34
  • 22 (a)
 ManyToMany
acp-1 34
  • 20 (a)
 ManyToMany
acp-3 34
  • 19 (a)
 ManyToMany
acp-2 34
  • 18 (a)
 ManyToMany
acp-4 34
  • 18 (a)
 ManyToMany
sea squirt
(Ciona savignyi)
 Ascidiacea -- 34
  • 34 (a)
 OneToMany
Species where no ortholog for ACP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ACP2 Gene

ENSEMBL:
Gene Tree for ACP2 (if available)
TreeFam:
Gene Tree for ACP2 (if available)

Paralogs for ACP2 Gene

Paralogs for ACP2 Gene

(2) SIMAP similar genes for ACP2 Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with ACP2: view

Variants for ACP2 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for ACP2 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1050244 likely-benign, Xeroderma pigmentosum 47,238,926(-) C/T downstream_transcript_variant
rs4647760 uncertain-significance, Xeroderma pigmentosum 47,239,000(-) C/A downstream_transcript_variant
rs4647761 uncertain-significance, Xeroderma pigmentosum 47,239,182(-) CAC/C downstream_transcript_variant
rs554676341 uncertain-significance, Xeroderma pigmentosum 47,238,975(-) T/C downstream_transcript_variant
rs1000214685 -- 47,250,638(-) A/C upstream_transcript_variant

Variation tolerance for ACP2 Gene

Residual Variation Intolerance Score: 34% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.87; 34.98% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ACP2 Gene

Human Gene Mutation Database (HGMD)
ACP2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ACP2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ACP2 Gene

Disorders for ACP2 Gene

MalaCards: The human disease database

(4) MalaCards diseases for ACP2 Gene - From: HGMD, OMIM, GTR, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
acid phosphatase deficiency
  • lysosomal acid phosphatase deficiency
phosphatase, acid, of tissues
  • lysosomal acid phosphatase
atrichia with papular lesions
  • apl
keratoconus
  • conical cornea
- elite association - COSMIC cancer census association via MalaCards
Search ACP2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

PPAL_HUMAN
  • Note=Lysosomal acid phosphatase has been shown to be deficient in cultured fibroblasts from patients manifesting intermittent vomiting, hypotonia, lethargy, opisthotonos, terminal bleeding and death in early infancy. {ECO:0000269 PubMed:5410815}.

Genatlas disease for ACP2 Gene

phosphatase acid,deficiency

Additional Disease Information for ACP2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ACP2: view

Publications for ACP2 Gene

  1. Polymorphisms in mitochondrial genes and prostate cancer risk. (PMID: 19064571) Wang L … Thibodeau SN (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008) 3 44 58
  2. Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms. (PMID: 17357082) Melquist S … Stephan DA (American journal of human genetics 2007) 3 22 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes. (PMID: 11801736) Obermüller S … Höning S (Journal of cell science 2002) 3 22 58
  5. Sequential processing of lysosomal acid phosphatase by a cytoplasmic thiol proteinase and a lysosomal aspartyl proteinase. (PMID: 2684640) Gottschalk S … von Figura K (The EMBO journal 1989) 3 4 58

Products for ACP2 Gene

Sources for ACP2 Gene

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