Aliases for ACOT12 Gene
- Acyl-CoA Thioesterase 12 2 3 4 5
- STARD15 2 3 4
- StAR-Related Lipid Transfer (START) Domain Containing 15 2 3
- START Domain-Containing Protein 15 3 4
- Cytoplasmic Acetyl-CoA Hydrolase 1 3 4
- Acyl-CoA Thioester Hydrolase 12 3 4
- Acyl-Coenzyme A Thioesterase 12 3 4
- Acetyl-Coenzyme A Thioesterase 3 4
- EC 18.104.22.168 4 50
External Ids for ACOT12 Gene
Previous GeneCards Identifiers for ACOT12 Gene
GeneCards Summary for ACOT12 Gene
ACOT12 (Acyl-CoA Thioesterase 12) is a Protein Coding gene. Diseases associated with ACOT12 include Leukoencephalopathy With Vanishing White Matter. Among its related pathways are Metabolism and Fatty Acyl-CoA Biosynthesis. Gene Ontology (GO) annotations related to this gene include lipid binding and acetyl-CoA hydrolase activity. An important paralog of this gene is ACOT11.
UniProtKB/Swiss-Prot Summary for ACOT12 Gene
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16951743). Acyl-coenzyme A thioesterase 12/ACOT12 preferentially hydrolyzes acetyl-CoA (PubMed:16951743).