Aliases for ACOT12 Gene
- Acyl-CoA Thioesterase 12 2 3 4 5
- STARD15 2 3 4
- StAR-Related Lipid Transfer (START) Domain Containing 15 2 3
- START Domain-Containing Protein 15 3 4
- Cytoplasmic Acetyl-CoA Hydrolase 1 3 4
- Acyl-CoA Thioester Hydrolase 12 3 4
- Acyl-Coenzyme A Thioesterase 12 3 4
- Acetyl-Coenzyme A Thioesterase 3 4
- EC 18.104.22.168 4 51
External Ids for ACOT12 Gene
Previous GeneCards Identifiers for ACOT12 Gene
GeneCards Summary for ACOT12 Gene
ACOT12 (Acyl-CoA Thioesterase 12) is a Protein Coding gene. Diseases associated with ACOT12 include Leukoencephalopathy With Vanishing White Matter. Among its related pathways are Metabolism and Pyruvate metabolism. Gene Ontology (GO) annotations related to this gene include lipid binding and acetyl-CoA hydrolase activity. An important paralog of this gene is ACOT11.
UniProtKB/Swiss-Prot Summary for ACOT12 Gene
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16951743). Acyl-coenzyme A thioesterase 12/ACOT12 preferentially hydrolyzes acetyl-CoA (PubMed:16951743).