Aliases for ACOT1 Gene
External Ids for ACOT1 Gene
Previous GeneCards Identifiers for ACOT1 Gene
GeneCards Summary for ACOT1 Gene
ACOT1 (Acyl-CoA Thioesterase 1) is a Protein Coding gene. Diseases associated with ACOT1 include Retinitis Pigmentosa 67 and Spindle Cell Hemangioma. Among its related pathways are alpha-linolenic acid (ALA) metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include hydrolase activity and palmitoyl-CoA hydrolase activity. An important paralog of this gene is ACOT2.
UniProtKB/Swiss-Prot Summary for ACOT1 Gene
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating intracellular levels of acyl-CoAs, free fatty acids and CoASH. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20).