Aliases for ACOT1 Gene
External Ids for ACOT1 Gene
Previous GeneCards Identifiers for ACOT1 Gene
GeneCards Summary for ACOT1 Gene
ACOT1 (Acyl-CoA Thioesterase 1) is a Protein Coding gene. Diseases associated with ACOT1 include Aztreonam Allergy and Cefuroxime Allergy. Among its related pathways are palmitate biosynthesis and Ovarian steroidogenesis. Gene Ontology (GO) annotations related to this gene include hydrolase activity and palmitoyl-CoA hydrolase activity. An important paralog of this gene is ACOT2.
UniProtKB/Swiss-Prot Summary for ACOT1 Gene
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating intracellular levels of acyl-CoAs, free fatty acids and CoASH. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20).