Aliases for ACAP1 Gene
External Ids for ACAP1 Gene
Previous HGNC Symbols for ACAP1 Gene
Previous GeneCards Identifiers for ACAP1 Gene
GeneCards Summary for ACAP1 Gene
ACAP1 (ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 1) is a Protein Coding gene. Diseases associated with ACAP1 include Ileum Cancer. Among its related pathways are Arf6 trafficking events and Nucleotide-binding Oligomerization Domain (NOD) pathway. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ACAP2.
UniProtKB/Swiss-Prot Summary for ACAP1 Gene
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.