Aliases for ACAP1 Gene
External Ids for ACAP1 Gene
Previous HGNC Symbols for ACAP1 Gene
Previous GeneCards Identifiers for ACAP1 Gene
GeneCards Summary for ACAP1 Gene
ACAP1 (ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 1) is a Protein Coding gene. Diseases associated with ACAP1 include Ileum Cancer. Among its related pathways are Arf6 signaling events and Arf6 trafficking events. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ACAP2.
UniProtKB/Swiss-Prot Summary for ACAP1 Gene
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.