Aliases for ABTB1 Gene
External Ids for ABTB1 Gene
Previous GeneCards Identifiers for ABTB1 Gene
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
GeneCards Summary for ABTB1 Gene
ABTB1 (Ankyrin Repeat And BTB Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include translation elongation factor activity. An important paralog of this gene is ABTB2.
UniProtKB/Swiss-Prot Summary for ABTB1 Gene
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.