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ABLIM2 (Actin Binding LIM Protein Family Member 2) is a Protein Coding gene. Among its related pathways are Netrin-1 signaling and Axon guidance. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is ABLIM1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003779 | actin binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO:0051015 | actin filament binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA | -- |
GO:0015629 | actin cytoskeleton | IDA | 17194709 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Developmental Biology |
.51
|
|
2 | Netrin-1 signaling | ||
3 | Axon guidance | ||
4 | Netrin Signaling |
Netrin Signaling
-
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0007010 | cytoskeleton organization | IEA | -- |
GO:0030032 | lamellipodium assembly | IBA | 21873635 |
GO:0030036 | actin cytoskeleton organization | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ABLIM2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ABLIM2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | ABLIM2 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Ablim2 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ablim2 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | ABLIM2 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
Chicken (Gallus gallus) |
Aves | ABLIM2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | ABLIM2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ablim2 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | ablim2 30 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs750016618 | Uncertain Significance: Severe Myopia | 7,983,304(-) | C/T | MISSENSE_VARIANT | |
rs757430763 | A pancreatic ductal adenocarcinoma sample | p.Gly227Arg | |||
VAR_062666 | A pancreatic ductal adenocarcinoma sample | p.Lys274Met |
No disorders were found for ABLIM2 Gene.