Aliases for ABHD3 Gene
External Ids for ABHD3 Gene
Previous GeneCards Identifiers for ABHD3 Gene
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABHD3 Gene
ABHD3 (Abhydrolase Domain Containing 3, Phospholipase) is a Protein Coding gene. Among its related pathways are Synthesis of PC and Metabolism. Gene Ontology (GO) annotations related to this gene include carboxylic ester hydrolase activity and phospholipase A1 activity. An important paralog of this gene is ABHD1.
UniProtKB/Swiss-Prot Summary for ABHD3 Gene
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.