Aliases for ABCG4 Gene
External Ids for ABCG4 Gene
Previous GeneCards Identifiers for ABCG4 Gene
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. [provided by RefSeq, Jan 2017]
GeneCards Summary for ABCG4 Gene
ABCG4 (ATP Binding Cassette Subfamily G Member 4) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and ATPase activity. An important paralog of this gene is ABCG1.
UniProtKB/Swiss-Prot Summary for ABCG4 Gene
May be involved in macrophage lipid homeostasis.