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This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided b... See more...
Aliases for ABCF3 Gene
Aliases for ABCF3 Gene
External Ids for ABCF3 Gene
- HGNC: 72
- Entrez Gene: 55324
- Ensembl: ENSG00000161204
- UniProtKB: Q9NUQ8
Previous GeneCards Identifiers for ABCF3 Gene
- GC03U990120
- GC03P185305
- GC03P185224
- GC03P185386
- GC03P183903
- GC03P181310
Summaries for ABCF3 Gene
-
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
GeneCards Summary for ABCF3 Gene
ABCF3 (ATP Binding Cassette Subfamily F Member 3) is a Protein Coding gene. Diseases associated with ABCF3 include Abcd Syndrome and Microcephaly, Autosomal Dominant. Gene Ontology (GO) annotations related to this gene include ATPase activity. An important paralog of this gene is ABCF1.
UniProtKB/Swiss-Prot Summary for ABCF3 Gene
-
Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.
Additional gene information for ABCF3 Gene
- HGNC(72)
- Entrez Gene(55324)
- Ensembl(ENSG00000161204)
- UniProtKB(Q9NUQ8)
- Open Targets Platform(ENSG00000161204)
- Search for ABCF3 at DataMed
- Search for ABCF3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ABCF3 Gene
Genomics for ABCF3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ABCF3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ABCF3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ABCF3
- Top Transcription factor binding sites by QIAGEN in the ABCF3 gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- FAC1
- Lmo2
- SEF-1 (1)
- Sox9
Genomic Locations for ABCF3 Gene
Genomic Locations for ABCF3 Gene
- chr3:184,186,023-184,194,012
- (GRCh38/hg38)
- Size:
- 7,990 bases
- Orientation:
- Plus strand
- chr3:183,903,811-183,911,800
- (GRCh37/hg19)
- Size:
- 7,990 bases
- Orientation:
- Plus strand
Genomic View for ABCF3 Gene
Genes around ABCF3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q27.1 by HGNC
- 3q27.1 by Entrez Gene
- 3q27.1 by Ensembl
ABCF3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ABCF3 Gene
Proteins for ABCF3 Gene
-
Protein details for ABCF3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NUQ8-ABCF3_HUMAN
- Recommended name:
- ATP-binding cassette sub-family F member 3
- Protein Accession:
- Q9NUQ8
- A8K241
- Q86UA2
- Q8NAN1
- Q96GS8
- Q9H7A8
Protein attributes for ABCF3 Gene
- Size:
- 709 amino acids
- Molecular mass:
- 79745 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB14989.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ABCF3 Gene
Selected DME Specific Peptides for ABCF3 Gene
- Q9NUQ8:
-
- NGAGKST
- GENGAGKST
- LLLLDEP
Post-translational modifications for ABCF3 Gene
Other Protein References for ABCF3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ ABCF3 Antibody
- Novus Biologicals Antibodies for ABCF3
- Invitrogen Antibodies for ABCF3 (AFLGC-ABCF3)
- antibodies-online: Show 13 available ABCF3 Antibodies ranked by validation data
-
Biorbyt antibodies for ABCF3
-
Boster Bio Antibodies for ABCF3
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for ABCF3
- Origene Custom Protein Services for ABCF3
-
Signalway Proteins for ABCF3
Domains & Families for ABCF3 Gene
Gene Families for ABCF3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for ABCF3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ABCF3 Gene
- GenScript: Design optimal peptide antigens:
-
- ATP-binding cassette sub-family F member 3 (ABCF3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9NUQ8UniProtKB/Swiss-Prot:
ABCF3_HUMAN :- Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
- Family:
-
- Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Function for ABCF3 Gene
Molecular function for ABCF3 Gene
- UniProtKB/Swiss-Prot Function:
- Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.
- GENATLAS Biochemistry:
- ATP-binding cassette superfamily,subfamily F (GCN20),member 3
Enzyme Numbers (IUBMB) for ABCF3 Gene
Phenotypes From GWAS Catalog for ABCF3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 21516116 |
| GO:0005524 | ATP binding | IBA | 21873635 |
| GO:0016887 | ATPase activity | IEA | -- |
| GO:0045296 | cadherin binding | HDA | 25468996 |
Phenotypes for ABCF3 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for ABCF3
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ABCF3 - Select products 50% OFF >
- * ABCF3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ABCF3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ABCF3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ABCF3
miRNA for ABCF3 Gene
- miRTarBase miRNAs that target ABCF3
-
- mmu-miR-34b-5p (MIRT012748)
- hsa-miR-4252 (MIRT091309)
- hsa-miR-155-3p (MIRT607597)
- hsa-miR-3941 (MIRT607598)
- hsa-miR-6845-3p (MIRT607599)
- hsa-miR-603 (MIRT607600)
- hsa-miR-362-3p (MIRT607601)
- hsa-miR-329-3p (MIRT607602)
- hsa-miR-8485 (MIRT607603)
- hsa-miR-6818-3p (MIRT608645)
- hsa-miR-548s (MIRT608646)
- hsa-miR-6864-3p (MIRT608647)
- hsa-miR-3672 (MIRT608648)
- hsa-miR-6888-3p (MIRT608649)
- hsa-miR-4684-5p (MIRT608650)
- hsa-miR-593-3p (MIRT608651)
- hsa-miR-6895-3p (MIRT608652)
- hsa-miR-3926 (MIRT608653)
- hsa-miR-769-5p (MIRT608654)
- hsa-miR-4786-5p (MIRT608655)
- hsa-miR-4738-3p (MIRT608656)
- hsa-miR-3120-5p (MIRT608657)
- hsa-miR-3190-5p (MIRT608658)
- hsa-miR-6849-3p (MIRT608659)
- hsa-miR-3664-5p (MIRT608660)
- hsa-miR-6510-3p (MIRT643618)
- hsa-miR-6873-3p (MIRT643619)
- hsa-miR-4522 (MIRT643620)
- hsa-miR-6817-3p (MIRT643621)
- hsa-miR-7110-3p (MIRT643622)
- hsa-miR-7703 (MIRT670080)
- hsa-miR-6720-5p (MIRT670081)
- hsa-miR-6512-3p (MIRT670082)
- hsa-miR-196a-3p (MIRT670083)
- hsa-miR-661 (MIRT670084)
- hsa-miR-6860 (MIRT670085)
- hsa-miR-612 (MIRT670086)
- hsa-miR-5189-5p (MIRT670087)
- hsa-miR-3187-5p (MIRT670088)
- hsa-miR-1285-3p (MIRT670089)
- hsa-miR-4793-3p (MIRT670090)
- hsa-miR-766-3p (MIRT670091)
- hsa-miR-1292-3p (MIRT670092)
- hsa-miR-939-3p (MIRT670093)
- hsa-miR-1273g-3p (MIRT670094)
- hsa-miR-3065-5p (MIRT670095)
- hsa-miR-508-5p (MIRT670096)
- hsa-miR-6827-3p (MIRT674177)
- hsa-miR-340-3p (MIRT674178)
- hsa-miR-1229-3p (MIRT761447)
- hsa-miR-1273e (MIRT761817)
- hsa-miR-1285-5p (MIRT762233)
- hsa-miR-3689d (MIRT767048)
- hsa-miR-377-5p (MIRT767348)
- hsa-miR-4537 (MIRT770115)
- hsa-miR-455-3p (MIRT770254)
- hsa-miR-4695-3p (MIRT771138)
- hsa-miR-6086 (MIRT775479)
- hsa-miR-6134 (MIRT775922)
- hsa-miR-6499-3p (MIRT776183)
- hsa-miR-6511a-3p (MIRT776751)
- hsa-miR-6511b-3p (MIRT776869)
- hsa-miR-6516-5p (MIRT777049)
- hsa-miR-665 (MIRT777520)
- hsa-miR-6784-3p (MIRT779084)
- hsa-miR-6840-3p (MIRT780101)
- hsa-miR-6851-5p (MIRT780386)
- hsa-miR-6862-3p (MIRT780594)
- hsa-miR-6880-5p (MIRT780811)
- hsa-miR-7847-3p (MIRT782129)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ABCF3
- Browse OriGene Inhibitory RNA Products For ABCF3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ABCF3
Clone Products
- Applied Biological Materials (abm): Clones for ABCF3 - Select products 50% OFF >
- * ABCF3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ABCF3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ABCF3
Cell Line Products
-
Horizon Cell Lines for ABCF3
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ABCF3 Gene
Localization for ABCF3 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
- Nucleoli (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | HDA | 19946888 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for ABCF3 Gene
Pathways & Interactions for ABCF3 Gene
Interacting Proteins for ABCF3 Gene
Selected Interacting proteins:
Q9NUQ8-ABCF3_HUMAN
ENSP00000411471
for ABCF3 Gene via
UniProtKB
MINT
STRING
IID
| Symbol | External ID(s) | Details |
|---|---|---|
| CDC5L | ||
| FCHSD2 | ||
| SNW1 | ||
| TRIM27 | ||
| ABCF2-H2BE1 |
GPS-Prot Interaction Network for ABCF3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0051607 | defense response to virus | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for ABCF3 Gene
Transcripts for ABCF3 Gene
mRNA/cDNA for ABCF3 Gene
- 4 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000429586 2624 nts (view in UCSC)
- ENST00000421340 690 nts (view in UCSC)
- ENST00000485921 813 nts (view in UCSC)
- ENST00000463685 661 nts (view in UCSC)
- ENST00000478288 754 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ABCF3 - Select products 50% OFF >
- * ABCF3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ABCF3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ABCF3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ABCF3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ABCF3
- Browse OriGene Inhibitory RNA Products For ABCF3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ABCF3
Clone Products
- Applied Biological Materials (abm): Clones for ABCF3 - Select products 50% OFF >
- * ABCF3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ABCF3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ABCF3
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: |
| ExUns: | 14a | · | 14b | · | 14c | · | 14d | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22a | · | 22b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||||
| SP16: | |||||||||||||||||||||||||||||||
| SP17: | |||||||||||||||||||||||||||||||
| SP18: | |||||||||||||||||||||||||||||||
| SP19: | |||||||||||||||||||||||||||||||
| SP20: | - |
Relevant External Links for ABCF3 Gene
- GeneLoc Exon Structure for
- ABCF3
Expression for ABCF3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Head Mesenchyme (Muscoskeletal System)
- Gut Tube (Gastrointestinal Tract)
-
Adrenal Gland (Endocrine System)
-
Limb (Muscoskeletal System)
This gene is overexpressed in Peripheral blood mononuclear cells (15.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ABCF3 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ABCF3
SOURCE GeneReport for Unigene cluster for ABCF3 Gene:
Hs.361323Evidence on tissue expression from TISSUES for ABCF3 Gene
- Nervous system(4.9)
- Muscle(4.4)
- Skin(4.4)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for ABCF3
-
OriGene qPCR primer pairs and template standards for ABCF3
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ABCF3 Gene
Orthologs for ABCF3 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ABCF3 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ABCF3 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ABCF3 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ABCF3 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Abcf3 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Abcf3 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ABCF3 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | ABCF3 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ABCF3 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100145696 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC398565 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | ABCF3 31 |
|
OneToOne | |
| LOC100331227 30 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP012005 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG9330 30 31 |
|
OneToOne | |
| Worm (Caenorhabditis elegans) |
Secernentea | abcf-3 30 31 |
|
OneToOne | |
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AEL032W 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | GCN20 30 31 33 |
|
OneToMany | |
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A10857g 30 |
|
||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | GCN3 30 |
|
||
| Soybean (Glycine max) |
eudicotyledons | Gma.4290 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os.10758 30 |
|
||
| Corn (Zea mays) |
Liliopsida | Zm.4768 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.1523 31 |
|
OneToOne | |
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU04051 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPBC29A3.09c 30 |
|
||
| Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.11475 30 |
|
- Species where no ortholog for ABCF3 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ABCF3 Gene
- ENSEMBL:
- Gene Tree for ABCF3 (if available)
- TreeFam:
- Gene Tree for ABCF3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ABCF3: view image
Paralogs for ABCF3 Gene
Variants for ABCF3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ABCF3 Gene
| SNP ID | Clinical significance and condition | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs143852274 | Uncertain Significance: Malignant tumor of prostate | 184,189,867(+) | C/T | MISSENSE_VARIANT | |
| rs11706273 | - | p.Pro503Leu | |||
| rs9811715 | - | p.Arg510His |
Residual Variation Intolerance Score:
26.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.80;
58.27% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ABCF3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ABCF3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABCF3 Gene
Disorders for ABCF3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| abcd syndrome |
|
|
| microcephaly, autosomal dominant |
|
|
| hemophagocytic lymphohistiocytosis, familial, 3 |
|
|
Search ABCF3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ABCF3
No data available for UniProtKB/Swiss-Prot and Genatlas for ABCF3 Gene
Publications for ABCF3 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. (PMID: 8894702) Allikmets R … Dean M (Human molecular genetics 1996) 2 3
- BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion. (PMID: 31519766) Chan CJ … Melançon P (Molecular & cellular proteomics : MCP 2019) 3
- PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. (PMID: 31091453) Shami Shah A … Baskin JM (Cell reports 2019) 3
ExternalLinks
Products for ABCF3 Gene
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Sources for ABCF3 Gene
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