This gene represents readthrough transcription between ABCF2 and a downstream histone H2B-like gene. [provided by RefSeq, Mar 2019] See more...

Aliases for ABCF2-H2BE1 Gene

Aliases for ABCF2-H2BE1 Gene

  • ABCF2-H2BE1 Readthrough 2 3
  • ATP-Binding Cassette Sub-Family F Member 2 4
  • ATP Binding Cassette Subfamily F Member 2 5
  • Iron-Inhibited ABC Transporter 2 4
  • ABCF2-H2B Readthrough 3
  • ABCF2-H2B Protein 3
  • EC 3.6.3.17 51
  • EC 3.6.3 51
  • ABCF2 5

External Ids for ABCF2-H2BE1 Gene

Summaries for ABCF2-H2BE1 Gene

Entrez Gene Summary for ABCF2-H2BE1 Gene

  • This gene represents readthrough transcription between ABCF2 and a downstream histone H2B-like gene. [provided by RefSeq, Mar 2019]

GeneCards Summary for ABCF2-H2BE1 Gene

ABCF2-H2BE1 (ABCF2-H2BE1 Readthrough) is a Protein Coding gene. An important paralog of this gene is ABCF2.

Additional gene information for ABCF2-H2BE1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ABCF2-H2BE1 Gene

Genomics for ABCF2-H2BE1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ABCF2-H2BE1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J151225 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.0 1 3.2 CEBPG SP1 CREB1 PRDM10 REST ZNF629 SIX5 LEF1 SOX13 IKZF1 ABCF2 ABCF2-H2BE1 lnc-CHPF2-4 lnc-SMARCD3-1 H2BE1 RF00017-6756
GH07J151206 Enhancer 1 Ensembl ENCODE 0.4 +19.7 19705 2.6 PRDM10 LEF1 IKZF1 JUND PHF21A PKNOX1 MTA1 REST DPF2 HDAC1 IQCA1L ABCF2 GBX1 CHPF2 SMARCD3 ENSG00000243018 H2BE1 RF00017-6756 ABCF2-H2BE1
GH07J151223 Promoter 0.3 EPDnew 0.7 +3.4 3443 0.1 ABCF2 ABCF2-H2BE1 lnc-SMARCD3-1 H2BE1 RF00017-6756
GH07J151218 Promoter 0.3 EPDnew 0.4 +9.1 9078 0.1 ABCF2 ABCF2-H2BE1 H2BE1 lnc-SMARCD3-1 RF00017-6756
GH07J151210 Enhancer 0.3 Ensembl 0.4 +16.5 16504 1 SUPT5H ZNF148 H2BE1 ABCF2 RF00017-6756 ABCF2-H2BE1 lnc-SMARCD3-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ABCF2-H2BE1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ABCF2-H2BE1 Gene

Genomic Locations for ABCF2-H2BE1 Gene
chr7:151,207,837-151,227,205
(GRCh38/hg38)
Size:
19,369 bases
Orientation:
Minus strand

Genomic View for ABCF2-H2BE1 Gene

Genes around ABCF2-H2BE1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABCF2-H2BE1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABCF2-H2BE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABCF2-H2BE1 Gene

Proteins for ABCF2-H2BE1 Gene

  • Protein details for ABCF2-H2BE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UG63-ABCF2_HUMAN
    Recommended name:
    ATP-binding cassette sub-family F member 2
    Protein Accession:
    Q9UG63
    Secondary Accessions:
    • O60864
    • Q75MJ0
    • Q75MJ1
    • Q96TE8

    Protein attributes for ABCF2-H2BE1 Gene

    Size:
    623 amino acids
    Molecular mass:
    71290 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ABCF2-H2BE1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABCF2-H2BE1 Gene

Selected DME Specific Peptides for ABCF2-H2BE1 Gene

Q9UG63:
  • NGAGKST
  • NGAGKSTLLK
  • GPNGAGKS

Post-translational modifications for ABCF2-H2BE1 Gene

  • Ubiquitination at Lys315, Lys339, Lys365, Lys436, Lys508, Lys602, and Lys618
  • Modification sites at PhosphoSitePlus

Other Protein References for ABCF2-H2BE1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for ABCF2-H2BE1 Gene

Protein Domains for ABCF2-H2BE1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UG63

UniProtKB/Swiss-Prot:

ABCF2_HUMAN :
  • Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Family:
  • Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
genes like me logo Genes that share domains with ABCF2-H2BE1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for ABCF2-H2BE1 Gene

Function for ABCF2-H2BE1 Gene

Enzyme Numbers (IUBMB) for ABCF2-H2BE1 Gene

Phenotypes From GWAS Catalog for ABCF2-H2BE1 Gene

Gene Ontology (GO) - Molecular Function for ABCF2-H2BE1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0005524 ATP binding IBA --
GO:0016887 ATPase activity IEA --
genes like me logo Genes that share ontologies with ABCF2-H2BE1: view

miRNA for ABCF2-H2BE1 Gene

miRTarBase miRNAs that target ABCF2-H2BE1

No data available for Molecular function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ABCF2-H2BE1 Gene

Localization for ABCF2-H2BE1 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ABCF2-H2BE1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane HDA --
genes like me logo Genes that share ontologies with ABCF2-H2BE1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ABCF2-H2BE1 Gene

Pathways & Interactions for ABCF2-H2BE1 Gene

PathCards logo

SuperPathways for ABCF2-H2BE1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ABCF2-H2BE1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ABCF2-H2BE1 Gene

Drugs & Compounds for ABCF2-H2BE1 Gene

No Compound Related Data Available

Transcripts for ABCF2-H2BE1 Gene

mRNA/cDNA for ABCF2-H2BE1 Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ABCF2-H2BE1 Gene

No ASD Table

Relevant External Links for ABCF2-H2BE1 Gene

GeneLoc Exon Structure for
ABCF2-H2BE1

Expression for ABCF2-H2BE1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ABCF2-H2BE1 Gene

Orthologs for ABCF2-H2BE1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ABCF2-H2BE1 Gene

Organism Taxonomy Gene Similarity Type Details
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ARB1 33
Species where no ortholog for ABCF2-H2BE1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for ABCF2-H2BE1 Gene

ENSEMBL:
Gene Tree for ABCF2-H2BE1 (if available)
TreeFam:
Gene Tree for ABCF2-H2BE1 (if available)

Paralogs for ABCF2-H2BE1 Gene

Paralogs for ABCF2-H2BE1 Gene

genes like me logo Genes that share paralogs with ABCF2-H2BE1: view

Variants for ABCF2-H2BE1 Gene

Additional dbSNP identifiers (rs#s) for ABCF2-H2BE1 Gene

Additional Variant Information for ABCF2-H2BE1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ABCF2-H2BE1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for ABCF2-H2BE1 Gene

Disorders for ABCF2-H2BE1 Gene

Additional Disease Information for ABCF2-H2BE1

No disorders were found for ABCF2-H2BE1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ABCF2-H2BE1 Gene

Publications for ABCF2-H2BE1 Gene

  1. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4
  2. N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P … Aldabe R (Proceedings of the National Academy of Sciences of the United States of America 2012) 4
  3. Initial characterization of the human central proteome. (PMID: 21269460) Burkard TR … Colinge J (BMC systems biology 2011) 4
  4. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PMID: 19608861) Choudhary C … Mann M (Science (New York, N.Y.) 2009) 4
  5. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4

No data available for Mastermind for ABCF2-H2BE1 Gene

Products for ABCF2-H2BE1 Gene

Sources for ABCF2-H2BE1 Gene