Aliases for ABCD3 Gene
Aliases for ABCD3 Gene
- ATP Binding Cassette Subfamily D Member 3 2 3 5
- ATP-Binding Cassette, Sub-Family D (ALD), Member 3 2 3
- 70 KDa Peroxisomal Membrane Protein 3 4
- PXMP1 3 4
- PMP70 3 4
- DJ824O18.1 (ATP-Binding Cassette, Sub-Family D (ALD), Member 3 (PMP70, PXMP1)) 3
- Peroxisomal Membrane Protein 1 (70kD, Zellweger Syndrome) 3
External Ids for ABCD3 Gene
- HGNC: 67
- Entrez Gene: 5825
- Ensembl: ENSG00000117528
- OMIM: 170995
- UniProtKB: P28288
Previous HGNC Symbols for ABCD3 Gene
- PXMP1
Previous GeneCards Identifiers for ABCD3 Gene
- GC01P095285
- GC01P094089
- GC01P094234
- GC01P094596
- GC01P094656
- GC01P094883
- GC01P093005
Summaries for ABCD3 Gene
-
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABCD3 Gene
ABCD3 (ATP Binding Cassette Subfamily D Member 3) is a Protein Coding gene. Diseases associated with ABCD3 include Bile Acid Synthesis Defect, Congenital, 5 and Zellweger Syndrome. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Peroxisome. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and ATPase activity, coupled to transmembrane movement of substances. An important paralog of this gene is ABCD2.
UniProtKB/Swiss-Prot for ABCD3 Gene
-
Probable transporter involved in the transport of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter function is a crucial step in bile acid biosynthesis (PubMed:25168382). The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity (PubMed:11248239).
Additional gene information for ABCD3 Gene
- Monarch Initiative
- Search for ABCD3 at DataMed
- Search for ABCD3 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ABCD3 Gene
Genomics for ABCD3 Gene
GeneHancer (GH) Regulatory Elements for ABCD3 Gene
Promoters and enhancers for ABCD3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ABCD3 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ABCD3 gene promoter:
Regulatory Element Products
Genomic Locations for ABCD3 Gene
Genomic Locations for ABCD3 Gene
- chr1:94,418,086-94,518,666
- (GRCh38/hg38)
- Size:
- 100,581 bases
- Orientation:
- Plus strand
- chr1:94,883,933-94,984,222
- (GRCh37/hg19)
Genomic View for ABCD3 Gene
Genes around ABCD3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p21.3 by Ensembl
- 1p21.3 by Entrez Gene
- 1p21.3 by HGNC
ABCD3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ABCD3 Gene
Proteins for ABCD3 Gene
-
Protein details for ABCD3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P28288-ABCD3_HUMAN
- Recommended name:
- ATP-binding cassette sub-family D member 3
- Protein Accession:
- P28288
- D3DT46
- Q15271
- Q6NUN5
- Q96DA3
- Q9H529
Protein attributes for ABCD3 Gene
- Size:
- 659 amino acids
- Molecular mass:
- 75476 Da
- Quaternary structure:
-
- Can form heterodimers with ABCD1/ALD and ABCD2/ALDR. Dimerization is necessary to form an active transporter. Interacts with PEX19.
- Miscellaneous:
-
- Mutation in ABCD3 have been found in two individuals affected by Zellweger syndrome. However, the role of ABCD3 in the causation of Zellweger syndrome remains uncertain.
Protein Expression for ABCD3 Gene
Post-translational modifications for ABCD3 Gene
Other Protein References for ABCD3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ABCD3
-
Abcam antibodies for ABCD3
- Invitrogen Antibodies for ABCD3
- GeneTex ABCD3 antibody for ABCD3
-
Santa Cruz Biotechnology (SCBT) Antibodies for ABCD3
Protein Products
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-
Abcam proteins for ABCD3
Assay Products
No data available for DME Specific Peptides for ABCD3 Gene
Domains & Families for ABCD3 Gene
Gene Families for ABCD3 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Disease related genes
- Potential drug targets
- Predicted membrane proteins
- Transporters
Protein Domains for ABCD3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ABCD3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P28288UniProtKB/Swiss-Prot:
ABCD3_HUMAN :- Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
- Family:
-
- Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
Function for ABCD3 Gene
Molecular function for ABCD3 Gene
- GENATLAS Biochemistry:
- ATP binding cassette superfamily,subfamily D (ALD),member 3,peroxisomal membrane protein,involved in the peroxisomal import of fatty acid or fatty acyl coA,see ZWS2
- UniProtKB/Swiss-Prot Function:
- Probable transporter involved in the transport of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter function is a crucial step in bile acid biosynthesis (PubMed:25168382). The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity (PubMed:11248239).
Phenotypes From GWAS Catalog for ABCD3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005324 | long-chain fatty acid transporter activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 10551832 |
| GO:0005524 | ATP binding | IDA | 11248239 |
| GO:0016887 | ATPase activity | IDA | 11248239 |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | -- |
Phenotypes for ABCD3 Gene
- MGI mutant phenotypes for ABCD3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ABCD3:
Animal Models for ABCD3 Gene
- MGI Knock Outs for ABCD3:
-
- Abcd3 tm1Safe
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ABCD3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCD3 gene
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-
OriGene CRISPR knockouts for ABCD3
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-
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miRNA for ABCD3 Gene
- miRTarBase miRNAs that target ABCD3
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Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for available ABCD3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCD3 gene
Clone Products
- Sino Biological Human cDNA Clone for ABCD3
- VectorBuilder custom plasmid, inducible vectors for ABCD3
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available ABCD3 gene related products
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- Applied Biological Materials Clones for ABCD3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for ABCD3
-
ViGene Biosciences adenoviral particle packaged cDNA for ABCD3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ABCD3 gene
-
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No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ABCD3 Gene
Localization for ABCD3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ABCD3 Gene
- Peroxisome membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| peroxisome | 5 |
| cytosol | 5 |
| mitochondrion | 4 |
| plasma membrane | 1 |
| extracellular | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
- Peroxisomes (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005743 | mitochondrial inner membrane | IEA | -- |
| GO:0005777 | peroxisome | IDA,IEA | 9425230 |
| GO:0005778 | peroxisomal membrane | TAS | -- |
| GO:0005782 | peroxisomal matrix | IDA | 9765053 |
Pathways & Interactions for ABCD3 Gene
Pathways by source for ABCD3 Gene
1 BioSystems pathway for ABCD3 Gene
3 Reactome pathways for ABCD3 Gene
2 KEGG pathways for ABCD3 Gene
Interacting Proteins for ABCD3 Gene
Selected Interacting proteins:
P28288-ABCD3_HUMAN
ENSP00000359233
for ABCD3 Gene via
IID
STRING
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006633 | fatty acid biosynthetic process | IMP | 25168382 |
| GO:0006635 | fatty acid beta-oxidation | IGI | 9425230 |
| GO:0006810 | transport | IEA | -- |
| GO:0007031 | peroxisome organization | IMP | 9765053 |
| GO:0014070 | response to organic cyclic compound | IEA | -- |
No data available for SIGNOR curated interactions for ABCD3 Gene
Transcripts for ABCD3 Gene
mRNA/cDNA for ABCD3 Gene
- (7) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (228) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ABCD3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ABCD3
- genomics-online: gRNA clones - Search results for available ABCD3 gene related products
- Applied Biological Materials CRISPR for ABCD3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ABCD3
- GenScript: Design CRISPR guide RNA sequences for ABCD3
miRNA Products
- Search ViGene Biosciences for ABCD3
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for ABCD3
- Browse OriGene Inhibitory RNA Products For ABCD3
- genomics-online: shRNA clones - Search results for available ABCD3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ABCD3 gene
Clone Products
- Sino Biological Human cDNA Clone for ABCD3
- VectorBuilder custom plasmid, inducible vectors for ABCD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ABCD3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available ABCD3 gene related products
- orf clones - Search results for available ABCD3 gene related products
- Applied Biological Materials Clones for ABCD3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: |
Expression for ABCD3 Gene
This gene is overexpressed in Nasal epithelium (51.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ABCD3 Gene
NURSA nuclear receptor signaling pathways regulating expression of ABCD3 Gene:
ABCD3SOURCE GeneReport for Unigene cluster for ABCD3 Gene:
Hs.700576Evidence on tissue expression from TISSUES for ABCD3 Gene
- Nervous system(4.9)
- Liver(4.6)
- Lung(4.4)
- Adrenal gland(2.7)
- Kidney(2.6)
- Stomach(2.5)
- Gall bladder(2.2)
- Intestine(2.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ABCD3 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cheek
- chin
- cranial nerve
- ear
- eye
- eyelid
- face
- forehead
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- outer ear
- skull
Thorax:
- chest wall
- clavicle
- lung
- rib
- rib cage
- scapula
- sternum
- thymus
Abdomen:
- kidney
- liver
- spleen
Pelvis:
- pelvis
- testicle
- vagina
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- blood
- peripheral nerve
- peripheral nervous system
- red blood cell
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for ABCD3
- genomics-online: primer clones - Search results for available ABCD3 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ABCD3 Gene
Orthologs for ABCD3 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ABCD3 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ABCD3 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ABCD3 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ABCD3 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ABCD3 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Abcd3 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Abcd3 33 16 34 |
|
||
| chicken (Gallus gallus) |
Aves | ABCD3 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ABCD3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | abcd3 33 |
|
||
| Str.14736 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.1498 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | abcd3b 34 |
|
OneToMany | |
| abcd3a 33 34 |
|
||||
| Dr.3614 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4773 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG12703 35 |
|
|
|
| Pmp70 33 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000440 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | pmp-2 33 34 |
|
||
| C44B7.9 35 |
|
|
|||
| C44B7.8 35 |
|
|
|||
| pmp-1 34 |
|
OneToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PXA1 34 |
|
OneToMany | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | PXA1 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os05g0107600 33 |
|
||
| Os.28988 33 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4944 33 |
|
- Species where no ortholog for ABCD3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ABCD3 Gene
(4) SIMAP similar genes for ABCD3 Gene using alignment to 3 proteins:
Variants for ABCD3 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs121917999 | uncertain-significance, Zellweger syndrome 2 | 94,418,528(+) | G/A | 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, intron_variant, missense_variant | |
| rs786200917 | uncertain-significance, Zellweger syndrome 2 | 94,515,203(+) | G/A | genic_downstream_transcript_variant, splice_donor_variant | |
| rs147055150 | likely-benign, not specified | 94,517,078(+) | C/G | coding_sequence_variant, genic_downstream_transcript_variant, synonymous_variant | |
| rs16946 | benign, not specified | 94,464,789(+) | G/A/T | 5_prime_UTR_variant, coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, synonymous_variant | |
| rs1000016176 | -- | 94,394,573(+) | T/C | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1930968 | CNV | deletion | 18987734 |
| esv2714951 | CNV | deletion | 23290073 |
| esv2714962 | CNV | deletion | 23290073 |
| esv2714973 | CNV | deletion | 23290073 |
| esv3120 | CNV | loss | 18987735 |
| esv3578013 | CNV | loss | 25503493 |
| nsv1122378 | CNV | deletion | 24896259 |
| nsv546851 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
16.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.05;
21.53% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ABCD3 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABCD3 Gene
Disorders for ABCD3 Gene
(6) MalaCards diseases for ABCD3 Gene - From: HGMD, OMIM, ClinVar, GTR, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| bile acid synthesis defect, congenital, 5 |
|
|
| zellweger syndrome |
|
|
| adrenoleukodystrophy |
|
|
| congenital bile acid synthesis defect |
|
|
| cerebral degeneration |
|
|
Search ABCD3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ABCD3_HUMAN- Congenital bile acid synthesis defect 5 (CBAS5) [MIM:616278]: An autosomal recessive disorder characterized by hepatosplenomegaly, hepatic fibrosis, progressive liver failure, and accumulation of peroxisomal C27-bile acid intermediates in plasma. {ECO:0000269 PubMed:25168382}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for ABCD3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for ABCD3 Gene
Publications for ABCD3 Gene
- Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. (PMID: 1301993) Gärtner J … Valle D (Nature genetics 1992) 2 3 4 22 58
- Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters. (PMID: 11248239) Roerig P … Gärtner J (FEBS letters 2001) 3 4 22 58
- Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p. (PMID: 10777694) Gloeckner CJ … Roscher AA (Biochemical and biophysical research communications 2000) 3 4 22 58
- Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1). (PMID: 9521874) Gärtner J … Valle D (Genomics 1998) 3 4 22 58
- Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters. (PMID: 1536884) Kamijo K … Hashimoto T (Biochimica et biophysica acta 1992) 3 4 22 58
Products for ABCD3 Gene
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ABCD3
- Novus Biologicals proteins for ABCD3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
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- Browse Peptides and Proteins
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- Abcam antibodies for ABCD3
- Abcam proteins for ABCD3
- Find your target
- Browse Primary Antibodies
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- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
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- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for ABCD3
- VectorBuilder custom plasmid, inducible vectors for ABCD3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ABCD3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 34 available ABCD3 Antibodies ranked by validation data
- Compare Top ABCD3 Antibodies
- antibodies-online: Search results for available ABCD3 related products ranked by validation data
- antibodies-online: Search results for available ABCD3 related products ranked by validation data
- GeneTex ABCD3 antibody for ABCD3
- Search GeneTex for Proteins for ABCD3
- ViGene Biosciences adenoviral particle packaged cDNA for ABCD3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ABCD3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ABCD3 gene
- Search ViGene Biosciences for ABCD3
- Santa Cruz Biotechnology (SCBT) Antibodies for ABCD3
- Search Santa Cruz Biotechnology (SCBT) for ABCD3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ABCD3
- Horizon Cell Lines for ABCD3
- genomics-online: cdna clones - Search results for available ABCD3 gene related products
- orf clones - Search results for available ABCD3 gene related products
- genomics-online: gRNA clones - Search results for available ABCD3 gene related products
- genomics-online: primer clones - Search results for available ABCD3 gene related products
- genomics-online: shRNA clones - Search results for available ABCD3 gene related products
Sources for ABCD3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
