This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. A... See more...

Aliases for ABCB8 Gene

Aliases for ABCB8 Gene

  • ATP Binding Cassette Subfamily B Member 8 2 3 5
  • MITOSUR 2 3 4
  • M-ABC1 2 3 4
  • MABC1 2 3 4
  • ATP-Binding Cassette Sub-Family B Member 8, Mitochondrial 3 4
  • ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 2 3
  • Mitochondrial Potassium Channel ATP-Binding Subunit 3 4
  • Mitochondrial ATP-Binding Cassette 1 3 4
  • Mitochondrial Sulfonylurea-Receptor 3 4
  • Mitochondrial ABC Protein 2 3
  • EST328128 2 3
  • EC 3.6.3 51
  • ABCB8 5

External Ids for ABCB8 Gene

Previous GeneCards Identifiers for ABCB8 Gene

  • GC07P148972
  • GC07P150040
  • GC07P150117
  • GC07P150164
  • GC07P150356
  • GC07P150725
  • GC07P144537

Summaries for ABCB8 Gene

Entrez Gene Summary for ABCB8 Gene

  • This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

GeneCards Summary for ABCB8 Gene

ABCB8 (ATP Binding Cassette Subfamily B Member 8) is a Protein Coding gene. Diseases associated with ABCB8 include Abcd Syndrome and Anemia, Sideroblastic, And Spinocerebellar Ataxia. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include transporter activity and ATPase activity, coupled to transmembrane movement of substances. An important paralog of this gene is ABCB9.

UniProtKB/Swiss-Prot Summary for ABCB8 Gene

  • ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). Plays a role in mitochondrial iron transport (PubMed:30623799). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).

Gene Wiki entry for ABCB8 Gene

Additional gene information for ABCB8 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ABCB8 Gene

Genomics for ABCB8 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ABCB8 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ABCB8 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ABCB8

Top Transcription factor binding sites by QIAGEN in the ABCB8 gene promoter:
  • AREB6
  • Arnt
  • E47
  • Lmo2
  • Pax-4a
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • USF1

Genomic Locations for ABCB8 Gene

Genomic Locations for ABCB8 Gene
chr7:151,028,422-151,047,782
(GRCh38/hg38)
Size:
19,361 bases
Orientation:
Plus strand
chr7:150,725,510-150,744,869
(GRCh37/hg19)
Size:
19,360 bases
Orientation:
Plus strand

Genomic View for ABCB8 Gene

Genes around ABCB8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ABCB8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ABCB8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ABCB8 Gene

Proteins for ABCB8 Gene

  • Protein details for ABCB8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NUT2-MITOS_HUMAN
    Recommended name:
    Mitochondrial potassium channel ATP-binding subunit
    Protein Accession:
    Q9NUT2
    Secondary Accessions:
    • A5D8W3
    • B2RBL8
    • B3KND2
    • B4DG02
    • G3XAP3
    • O95787
    • Q53GM0

    Protein attributes for ABCB8 Gene

    Size:
    735 amino acids
    Molecular mass:
    79989 Da
    Quaternary structure:
    • The mitochondrial potassium channel (mitoK(ATP)) is composed of 4 subunits of CCDC51/MITOK and 4 subunits of ABCB8/MITOSUR (Probable). Interacts with C10orf88/PAAT (PubMed:25063848). Interacts with NRP1; NRP1 regulates ABCB8/MITOSUR protein levels in mitochondria (PubMed:30623799).

    Three dimensional structures from OCA and Proteopedia for ABCB8 Gene

    Alternative splice isoforms for ABCB8 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ABCB8 Gene

Selected DME Specific Peptides for ABCB8 Gene

Q9NUT2:
  • IAHRLSTVR
  • VIAHRLST

Post-translational modifications for ABCB8 Gene

  • Ubiquitination at Lys247, Lys573, and Lys628
  • Modification sites at PhosphoSitePlus

Domains & Families for ABCB8 Gene

Gene Families for ABCB8 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Suggested Antigen Peptide Sequences for ABCB8 Gene

GenScript: Design optimal peptide antigens:
  • Mitochondrial ATP-binding cassette 1 (ABCB8_HUMAN)
  • cDNA FLJ14339 fis, clone SKNMC1000013, highly similar to ATP-binding cassette sub-family B member 8,mitochondrial (B3KND2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NUT2

UniProtKB/Swiss-Prot:

MITOS_HUMAN :
  • Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Family:
  • Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
genes like me logo Genes that share domains with ABCB8: view

Function for ABCB8 Gene

Molecular function for ABCB8 Gene

UniProtKB/Swiss-Prot Function:
ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). Plays a role in mitochondrial iron transport (PubMed:30623799). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).
UniProtKB/Swiss-Prot Induction:
SP1 transcription factor binds to the ABCB8 core promoter region, possibly regulating its transcription.
UniProtKB/Swiss-Prot EnzymeRegulation:
Channel activity inhibited by ATP via ABCB8/MITOSUR subunit.
GENATLAS Biochemistry:
ATP binding cassette superfamily,subfamily B (MDR/TAP),member 8,ubiquitously expressed,located in mitochondrial inner membrane

Enzyme Numbers (IUBMB) for ABCB8 Gene

Phenotypes From GWAS Catalog for ABCB8 Gene

Gene Ontology (GO) - Molecular Function for ABCB8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0005515 protein binding IPI 25063848
GO:0005524 ATP binding IDA 31435016
GO:0016887 ATPase activity IEA --
GO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA 21873635
genes like me logo Genes that share ontologies with ABCB8: view
genes like me logo Genes that share phenotypes with ABCB8: view

Animal Model Products

  • Taconic Biosciences Mouse Models for ABCB8

CRISPR Products

miRNA for ABCB8 Gene

miRTarBase miRNAs that target ABCB8

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ABCB8

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ABCB8 Gene

Localization for ABCB8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ABCB8 Gene

Mitochondrion inner membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ABCB8 gene
Compartment Confidence
plasma membrane 5
mitochondrion 5
nucleus 4
extracellular 1
cytoskeleton 1
peroxisome 1
endoplasmic reticulum 1
endosome 1
cytosol 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (3)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ABCB8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005730 nucleolus IDA --
GO:0005739 mitochondrion IEA,IDA --
GO:0005743 mitochondrial inner membrane IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with ABCB8: view

Pathways & Interactions for ABCB8 Gene

genes like me logo Genes that share pathways with ABCB8: view

Pathways by source for ABCB8 Gene

Gene Ontology (GO) - Biological Process for ABCB8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport IEA --
GO:0006813 potassium ion transport IEA --
GO:0055085 transmembrane transport IBA 21873635
GO:0071805 potassium ion transmembrane transport IDA 31435016
genes like me logo Genes that share ontologies with ABCB8: view

No data available for SIGNOR curated interactions for ABCB8 Gene

Drugs & Compounds for ABCB8 Gene

(1) Drugs for ABCB8 Gene - From: DrugBank

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Doxorubicin Approved, Investigational Pharma Transporter, substrate Topo II inhibitor,immunosuppresive antineoplastic antibiotic 2029
genes like me logo Genes that share compounds with ABCB8: view

Transcripts for ABCB8 Gene

mRNA/cDNA for ABCB8 Gene

4 REFSEQ mRNAs :
21 NCBI additional mRNA sequence :
22 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ABCB8

Alternative Splicing Database (ASD) splice patterns (SP) for ABCB8 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b ^ 7a · 7b · 7c ^
SP1: - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - - - - -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: - - - - - - - - - - - - - - - - - - -
SP11:
SP12: - - - -
SP13: - - - - - - - - - - - - - - - - -
SP14: - - - - - - - - - - - -
SP15: - -
SP16: - - - - - - - - - - - -
SP17: - - - - - - - - - - -
SP18: - - - - - - - - - - - - - - - - -
SP19: - -
SP20: - - - - - - - - - -
SP21:
SP22:
SP23: - - - - - - - -
SP24: - - - - - - - - -
SP25: - - - - - -
SP26: - - - - - -
SP27: - - - - - - - -

ExUns: 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22 ^ 23a · 23b · 23c ^
SP1: - - - - -
SP2: - - - - -
SP3: - - - - -
SP4: - - - - -
SP5:
SP6: -
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: -
SP22:
SP23:
SP24:
SP25:
SP26:
SP27:

ExUns: 24 ^ 25 ^ 26 ^ 27a · 27b ^ 28a · 28b ^ 29 ^ 30 ^ 31 ^ 32a · 32b · 32c
SP1:
SP2:
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:
SP26:
SP27:

Relevant External Links for ABCB8 Gene

GeneLoc Exon Structure for
ABCB8

Expression for ABCB8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ABCB8 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ABCB8 Gene

This gene is overexpressed in Serum (54.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ABCB8 Gene



Protein tissue co-expression partners for ABCB8 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ABCB8

SOURCE GeneReport for Unigene cluster for ABCB8 Gene:

Hs.647118

mRNA Expression by UniProt/SwissProt for ABCB8 Gene:

Q9NUT2-MITOS_HUMAN
Tissue specificity: Ubiquitous.

Evidence on tissue expression from TISSUES for ABCB8 Gene

  • Nervous system(4.9)
  • Kidney(4.4)
  • Skin(2.5)
  • Heart(2.1)
  • Muscle(2)
genes like me logo Genes that share expression patterns with ABCB8: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ABCB8 Gene

Orthologs for ABCB8 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ABCB8 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ABCB8 30 31
  • 99.35 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia ABCB8 30 31
  • 86.12 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia ABCB8 30 31
  • 85.69 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Abcb8 30 17 31
  • 83.03 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Abcb8 30
  • 82.96 (n)
Oppossum
(Monodelphis domestica)
Mammalia ABCB8 31
  • 70 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia ABCB8 31
  • 56 (a)
OneToOne
Chicken
(Gallus gallus)
Aves ABCB8 30
  • 70.68 (n)
Lizard
(Anolis carolinensis)
Reptilia ABCB8 31
  • 58 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia abcb8 30
  • 63.95 (n)
Zebrafish
(Danio rerio)
Actinopterygii abcb8 30 31
  • 65.57 (n)
OneToOne
Dr.18475 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006273 30
  • 56.9 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta CG1824 30 31 32
  • 56.88 (n)
OneToOne
CG10226 32
  • 54 (a)
Worm
(Caenorhabditis elegans)
Secernentea haf-6 30 31
  • 53.75 (n)
OneToOne
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MDL1 31
  • 28 (a)
ManyToMany
MDL2 31
  • 26 (a)
ManyToMany
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.6372 30
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 53 (a)
OneToOne
Species where no ortholog for ABCB8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for ABCB8 Gene

ENSEMBL:
Gene Tree for ABCB8 (if available)
TreeFam:
Gene Tree for ABCB8 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ABCB8: view image

Paralogs for ABCB8 Gene

(15) SIMAP similar genes for ABCB8 Gene using alignment to 13 proteins:

  • ABCB8_HUMAN
  • A5D8W3_HUMAN
  • B3KND2_HUMAN
  • C9JA03_HUMAN
  • C9JTY4_HUMAN
  • C9JYI3_HUMAN
  • E7ENE8_HUMAN
  • F2Z2Z1_HUMAN
  • F2Z3G8_HUMAN
  • F8WC43_HUMAN
  • G3XAP3_HUMAN
  • H7C5K9_HUMAN
  • L8EAK9_HUMAN
genes like me logo Genes that share paralogs with ABCB8: view

Variants for ABCB8 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ABCB8 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
727305 Benign: not provided 151,033,839(+) C/T SYNONYMOUS_VARIANT,INTRON_VARIANT
733966 Benign: not provided 151,033,812(+) C/T SYNONYMOUS_VARIANT,INTRON_VARIANT
734474 Likely Benign: not provided 151,045,241(+) C/T SYNONYMOUS_VARIANT
768217 Benign: not provided 151,044,104(+) A/G SYNONYMOUS_VARIANT
769736 Benign: not provided 151,033,625(+) G/A MISSENSE_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for ABCB8 Gene

Structural Variations from Database of Genomic Variants (DGV) for ABCB8 Gene

Variant ID Type Subtype PubMed ID
dgv3695n106 OTHER inversion 24896259
dgv6756n100 CNV gain 25217958
nsv1067934 OTHER inversion 25765185
nsv1151906 OTHER inversion 26484159
nsv524928 CNV gain 19592680
nsv526410 CNV loss 19592680
nsv609011 CNV loss 21841781
nsv831188 CNV loss 17160897
nsv951648 CNV deletion 24416366

Variation tolerance for ABCB8 Gene

Residual Variation Intolerance Score: 60.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.39; 77.03% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ABCB8 Gene

Human Gene Mutation Database (HGMD)
ABCB8
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ABCB8

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ABCB8 Gene

Disorders for ABCB8 Gene

MalaCards: The human disease database

(3) MalaCards diseases for ABCB8 Gene - From: DISEASES

Disorder Aliases PubMed IDs
abcd syndrome
  • abcds
anemia, sideroblastic, and spinocerebellar ataxia
  • asat
tick infestation
  • tick infestations
- elite association - COSMIC cancer census association via MalaCards
Search ABCB8 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for ABCB8

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with ABCB8: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ABCB8 Gene

Publications for ABCB8 Gene

  1. Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein. (PMID: 9878413) Hogue DL … Ling V (Journal of molecular biology 1999) 3 4 23
  2. Identification of an ATP-sensitive potassium channel in mitochondria. (PMID: 31435016) Paggio A … De Stefani D (Nature 2019) 3 4
  3. PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis. (PMID: 25063848) Yang X … Liang J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014) 3 4
  4. Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8. (PMID: 21046154) Sachrajda I … Ratajewski M (Molecular genetics and genomics : MGG 2011) 3 4
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41

Products for ABCB8 Gene

Sources for ABCB8 Gene