Aliases for ABCB10 Gene
External Ids for ABCB10 Gene
Previous GeneCards Identifiers for ABCB10 Gene
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABCB10 Gene
ABCB10 (ATP Binding Cassette Subfamily B Member 10) is a Protein Coding gene. Diseases associated with ABCB10 include Specific Developmental Disorder. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and ATPase activity. An important paralog of this gene is ABCB8.
UniProtKB/Swiss-Prot for ABCB10 Gene
May mediate critical mitochondrial transport functions related to heme biosynthesis.