Aliases for ABCA10 Gene
External Ids for ABCA10 Gene
Previous GeneCards Identifiers for ABCA10 Gene
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008]
GeneCards Summary for ABCA10 Gene
ABCA10 (ATP Binding Cassette Subfamily A Member 10) is a Protein Coding gene. Diseases associated with ABCA10 include Donnai-Barrow Syndrome. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include ATPase activity and ATPase activity, coupled to transmembrane movement of substances. An important paralog of this gene is ABCA9.
UniProtKB/Swiss-Prot Summary for ABCA10 Gene
Probable transporter which may play a role in macrophage lipid homeostasis.