Aliases for AATK Gene
External Ids for AATK Gene
Previous GeneCards Identifiers for AATK Gene
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for AATK Gene
AATK (Apoptosis Associated Tyrosine Kinase) is a Protein Coding gene. Diseases associated with AATK include Neuroblastoma. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is LMTK3.
UniProtKB/Swiss-Prot Summary for AATK Gene
May be involved in neuronal differentiation.