Aliases for AASDHPPT Gene
External Ids for AASDHPPT Gene
Previous GeneCards Identifiers for AASDHPPT Gene
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for AASDHPPT Gene
AASDHPPT (Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase) is a Protein Coding gene. Diseases associated with AASDHPPT include Pipecolic Acidemia and Chronic Maxillary Sinusitis. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include magnesium ion binding and holo-[acyl-carrier-protein] synthase activity.
UniProtKB/Swiss-Prot for AASDHPPT Gene
Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.