Aliases for AASDH Gene
External Ids for AASDH Gene
Previous GeneCards Identifiers for AASDH Gene
This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues. [provided by RefSeq, Apr 2016]
GeneCards Summary for AASDH Gene
AASDH (Aminoadipate-Semialdehyde Dehydrogenase) is a Protein Coding gene. Diseases associated with AASDH include Hyperprolinemia, Type Ii and Hyperlysinemia, Type I. Gene Ontology (GO) annotations related to this gene include acid-thiol ligase activity. An important paralog of this gene is ACSF3.
UniProtKB/Swiss-Prot Summary for AASDH Gene
Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an, as yet, unknown acceptor. May be required for a post-translational protein modification or for post-transcriptional modification of an RNA.