Aliases for AANAT Gene
Aliases for AANAT Gene
External Ids for AANAT Gene
- HGNC: 19
- Entrez Gene: 15
- Ensembl: ENSG00000129673
- OMIM: 600950
- UniProtKB: Q16613
Previous GeneCards Identifiers for AANAT Gene
- GC17P074297
- GC17P077455
- GC17P074927
- GC17P075060
- GC17P071975
- GC17P074449
- GC17P069877
Summaries for AANAT Gene
-
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
GeneCards Summary for AANAT Gene
AANAT (Aralkylamine N-Acetyltransferase) is a Protein Coding gene. Diseases associated with AANAT include Dissociative Amnesia and Dissociative Disorder. Among its related pathways are Biogenic Amine Synthesis and Amine-derived hormones. Gene Ontology (GO) annotations related to this gene include N-acetyltransferase activity and arylamine N-acetyltransferase activity.
UniProtKB/Swiss-Prot for AANAT Gene
-
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
Additional gene information for AANAT Gene
- Monarch Initiative
- Search for AANAT at DataMed
- Search for AANAT at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AANAT Gene
Genomics for AANAT Gene
GeneHancer (GH) Regulatory Elements for AANAT Gene
Promoters and enhancers for AANAT Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around AANAT on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for AANAT Gene
Genomic Locations for AANAT Gene
- chr17:76,452,853-76,470,790
- (GRCh38/hg38)
- Size:
- 17,938 bases
- Orientation:
- Plus strand
- chr17:74,449,433-74,466,199
- (GRCh37/hg19)
Genomic View for AANAT Gene
Genes around AANAT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by Entrez Gene
- 17q25.1 by HGNC
- 17q25.1 by Ensembl
AANAT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AANAT Gene
Proteins for AANAT Gene
-
Protein details for AANAT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q16613-SNAT_HUMAN
- Recommended name:
- Serotonin N-acetyltransferase
- Protein Accession:
- Q16613
- A0AVF2
- J3KMZ5
- Q562F4
Protein attributes for AANAT Gene
- Size:
- 207 amino acids
- Molecular mass:
- 23344 Da
- Quaternary structure:
-
- Monomer (By similarity). Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ, preferentially when phosphorylated at Thr-31. Phosphorylation on Ser-205 also allows binding to YWHAZ, but with lower affinity. The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protects the enzyme from dephosphorylation and proteasomal degradation (By similarity). It may also prevent thiol-dependent inactivation (By similarity).
- SequenceCaution:
-
- Sequence=AAH69434.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Post-translational modifications for AANAT Gene
- cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for AANAT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for AANAT
- Invitrogen Antibodies for AANAT
- GeneTex Aanat Antibody for AANAT
Protein Products
-
OriGene Purified Proteins for AANAT
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- Novus Biologicals proteins for AANAT
- Search GeneTex for Proteins for AANAT
Assay Products
No data available for DME Specific Peptides for AANAT Gene
Domains & Families for AANAT Gene
Gene Families for AANAT Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for AANAT Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for AANAT Gene
Graphical View of Domain Structure for InterPro Entry
Q16613- Family:
-
- Belongs to the acetyltransferase family. AANAT subfamily.
Function for AANAT Gene
Molecular function for AANAT Gene
- UniProtKB/Swiss-Prot Function:
- Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Acetyl-CoA + a 2-arylethylamine = CoA + an N-acetyl-2-arylethylamine.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=0.13 mM for tryptamine {ECO:0000269 PubMed:11313340}; KM=2.6 mM for 5-hydroxytryptamine {ECO:0000269 PubMed:11313340}; KM=0.55 mM for phenylethylamine {ECO:0000269 PubMed:11313340}; KM=10.6 mM for tyramine {ECO:0000269 PubMed:11313340};
- GENATLAS Biochemistry:
- arylalkylamine N-acetyltransferase,23kDa,expressed in the pineal gland,penultimate step in melatonin synthesis,controlling the circadian rythm of production of melatonin,rhythmic activity controlled by ICER,an early response repressor
Enzyme Numbers (IUBMB) for AANAT Gene
Phenotypes From GWAS Catalog for AANAT Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004059 | aralkylamine N-acetyltransferase activity | TAS | -- |
| GO:0004060 | arylamine N-acetyltransferase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008080 | N-acetyltransferase activity | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for AANAT Gene
- MGI mutant phenotypes for AANAT:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for AANAT:
-
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased viability in esophageal squamous lineage
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability after Maraba virus infection
- Decreased NF-kappaB reporter expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
CRISPR Products
-
OriGene CRISPR knockouts for AANAT
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- genomics-online: gRNA clones - Search results for 100 available AANAT gene related products
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-
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miRNA for AANAT Gene
- miRTarBase miRNAs that target AANAT
miRNA Products
Inhibitory RNA Products
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Clone Products
- VectorBuilder custom plasmid, inducible vectors for AANAT
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-
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for AANAT
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AANAT Gene
Localization for AANAT Gene
Subcellular locations from UniProtKB/Swiss-Prot for AANAT Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA,IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0048471 | perinuclear region of cytoplasm | IDA | 11313340 |
Pathways & Interactions for AANAT Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | superpathway of tryptophan utilization | ||
| 2 | Amine-derived hormones | ||
| 3 | Metabolism |
.37
|
|
| 4 | Viral mRNA Translation | ||
| 5 | Biogenic Amine Synthesis | ||
Pathways by source for AANAT Gene
5 BioSystems pathways for AANAT Gene
4 Reactome pathways for AANAT Gene
2 KEGG pathways for AANAT Gene
UniProtKB/Swiss-Prot Q16613-SNAT_HUMAN
- Pathway: Aromatic compound metabolism; melatonin biosynthesis; melatonin from serotonin: step 1/2.
Interacting Proteins for AANAT Gene
Selected Interacting proteins:
Q16613-SNAT_HUMAN
ENSP00000250615
for AANAT Gene via
IID
UniProtKB
MINT
STRING
GPS-Prot Interaction Network for AANAT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006474 | N-terminal protein amino acid acetylation | IDA | 11313340 |
| GO:0007623 | circadian rhythm | NAS | 8661026 |
| GO:0009416 | response to light stimulus | IBA | -- |
| GO:0009648 | photoperiodism | IEA | -- |
| GO:0010043 | response to zinc ion | IEA | -- |
No data available for SIGNOR curated interactions for AANAT Gene
Drugs & Compounds for AANAT Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| cannabidiol | Approved, Investigational | Pharma | Partial agonist, Agonist, Antagonist, Channel blocker, Activator, Enzyme | 0 | ||
| Nabiximols | Approved, Investigational | Pharma | Enzyme | 0 | ||
| Coa-S-Acetyl 5-Bromotryptamine | Experimental | Pharma | Target | 0 | ||
| Coa-S-Acetyl Tryptamine | Experimental | Pharma | Target | 0 | ||
| Coa-S-Trimethylene-Acetyl-Tryptamine | Experimental | Pharma | Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| acetyl-coa |
|
72-89-9 | ||||
| n-acetylserotonin |
|
1210-83-9 | ||||
| 5-Methoxytryptamine |
|
608-07-1 |
|
Transcripts for AANAT Gene
mRNA/cDNA for AANAT Gene
- (16) Selected AceView cDNA sequences:
- (8) Additional mRNA sequences :
- (3) REFSEQ mRNAs :
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000250615 1913 bps (uc021udg.1)
- ENST00000392492 1005 bps (uc002jro.4)
- ENST00000585649 478 bps (uc060kjg.1)
- ENST00000587798 796 bps (uc060kjf.1)
Unigene Clusters for AANAT Gene
CRISPR Products
-
OriGene CRISPR knockouts for AANAT
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- genomics-online: gRNA clones - Search results for 100 available AANAT gene related products
- Overview of 100 available AANAT gene related products
- Applied Biological Materials CRISPR for AANAT
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for AANAT
- GenScript: Design CRISPR guide RNA sequences for AANAT
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for AANAT
- Browse OriGene Inhibitory RNA Products For AANAT
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AANAT
- genomics-online: shRNA clones - Search results for 100 available AANAT gene related products
- Overview of 100 available AANAT gene related products
Clone Products
- VectorBuilder custom plasmid, inducible vectors for AANAT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AANAT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AANAT
- Applied Biological Materials Clones for AANAT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for AANAT Gene
mRNA differential expression in normal tissues according to GTEx for AANAT Gene
This gene is overexpressed in Testis (x8.8).
NURSA nuclear receptor signaling pathways regulating expression of AANAT Gene:
AANATSOURCE GeneReport for Unigene cluster for AANAT Gene:
Hs.431417mRNA Expression by UniProt/SwissProt for AANAT Gene:
Q16613-SNAT_HUMAN
Tissue specificity:
Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland.
Evidence on tissue expression from TISSUES for AANAT Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for AANAT
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for AANAT Gene
Orthologs for AANAT Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AANAT 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Aanat 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Aanat 16 34 33 |
|
||
| dog (Canis familiaris) |
Mammalia | AANAT 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | LOC618594 33 |
|
||
| AANAT 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | AANAT 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | AANAT 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | AANAT 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | AANAT 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | aanat 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | aanat1 34 33 |
|
OneToMany | |
| aanat2 34 |
|
OneToMany | |||
| zgc73074 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.11691 33 |
|
- Species where no ortholog for AANAT was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for AANAT Gene
- ENSEMBL:
- Gene Tree for AANAT (if available)
- TreeFam:
- Gene Tree for AANAT (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for AANAT: view image
Paralogs for AANAT Gene
No data available for Paralogs for AANAT Gene
Variants for AANAT Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1001896063 | uncertain-significance, Howel-Evans syndrome | 76,470,907(+) | A/C | downstream_transcript_variant | |
| rs1009901117 | uncertain-significance, Howel-Evans syndrome | 76,470,931(+) | G/A/C | downstream_transcript_variant | |
| rs111924263 | benign, Howel-Evans syndrome | 76,471,053(+) | G/A/C | downstream_transcript_variant | |
| rs11553544 | likely-benign, Howel-Evans syndrome | 76,471,122(+) | C/T | downstream_transcript_variant | |
| rs137910466 | likely-benign, Howel-Evans syndrome | 76,470,922(+) | T/C | downstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1058263 | CNV | gain | 25217958 |
| nsv833549 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
83.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.59;
30.65% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for AANAT Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AANAT Gene
Disorders for AANAT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| dissociative amnesia |
|
|
| dissociative disorder |
|
|
| evans' syndrome |
|
|
| pineocytoma |
|
|
| advanced sleep phase syndrome |
|
|
Search AANAT in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for AANAT
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for AANAT Gene
Publications for AANAT Gene
- Significant association of the arylalkylamine N-acetyltransferase ( AA-NAT) gene with delayed sleep phase syndrome. (PMID: 12736803) Hohjoh H … Tokunaga K (Neurogenetics 2003) 3 4 22 44 58
- The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression. (PMID: 8661026) Coon SL … Rodriguez IR (Genomics 1996) 2 3 4 22 58
- Association study of tryptophan hydroxylase 1 and arylalkylamine N-acetyltransferase polymorphisms with adolescent idiopathic scoliosis in Han Chinese. (PMID: 18794762) Wang H … Qiu G (Spine 2008) 3 22 44 58
- Arylalkylamine N-acetyltransferase (AANAT) genotype as a personal trait in melatonin synthesis. (PMID: 18569588) Blomeke B … Roemer HC (Journal of toxicology and environmental health. Part A 2008) 3 22 44 58
- A naturally occurring -263G/C variant of the human AA-NAT gene and overnight melatonin production. (PMID: 14728993) Ying GW … Lee EJ (Molecular genetics and metabolism 2004) 3 22 44 58
Products for AANAT Gene
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- Mammalian expression: PiggyBac
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- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
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- Yeast expression
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Sources for AANAT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
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- (112) RVIS
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- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
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- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
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- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio