Aliases for AACS Gene
External Ids for AACS Gene
Previous GeneCards Identifiers for AACS Gene
GeneCards Summary for AACS Gene
AACS (Acetoacetyl-CoA Synthetase) is a Protein Coding gene. Diseases associated with AACS include Spinal Muscular Atrophy, Type Iii and Spinal Muscular Atrophy, Type Ii. Among its related pathways are Butanoate metabolism and Ketone body metabolism. Gene Ontology (GO) annotations related to this gene include butyrate-CoA ligase activity and acetoacetate-CoA ligase activity. An important paralog of this gene is ACSS2.
UniProtKB/Swiss-Prot Summary for AACS Gene
Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).