About GeneCardsFor over a decade, GeneCards has provided gene-centric information, automatically mined and integrated from a myriad of data sources, resulting in a web-based card for each of the tens of thousands of human gene entries.
The GeneCards database is developed and maintained in the Crown Human Genome Center at the Weizmann Institute of Science in Israel. Founded in 1997, the GeneCards project defined as its goal to integrate the fragments of information scattered over a variety of specialized databases into a coherent picture.
GeneCards Version 3 features a novel infrastructure, and a new speedy and sophisticated search engine. As a result of these improvements, the GeneCards user can now perform improved and better targeted queries, and evaluate search results in a more effective and user friendly manner.
GeneCards Hybrid SystemThis version is a hybrid system, in which the database, search, and minicards are new, but the actual cards remain the same as those in Version 2, with the addition of a search bar at the top of the page.
GeneCards Infrastructure and DatabaseIn GeneCards Versions 2.xx, information is stored in flat files, one file per gene, all indexed to enable full-text searches. GeneCards V3 uses a persistent object/relational model, attempting to model all of the data entities and relationships in an efficient manner so that the diverse functions of displaying single genes, extracting various slices of attributes of sets of genes, and performing well on both full text and field-specific searches are taken into account.
Commercial users can have access to the relational database in collaboration with LifeMap Sciences, Inc.
Citing GeneCards in the LiteratureIf you want to cite the GeneCards encyclopedia in a journal article or on-line publication, please note the URL www.genecards.org, and cite the relevant publication(s).
Linking to particular GeneCardsIf you are a Web developer and you want to make links to particular GeneCards, use
"http://www.genecards.org/cgi-bin/carddisp.pl?gene=XXX" (with XXX being the gene symbol).
To link using an external id, use
(where YYY is a UniProt accession, EntrezGene id, Ensembl id, or HGNC id).
Optionally, a source for the id can be specified by adding "&id_type=" to the url. The possible types are "uniprot", "entrezgene", "ensembl", and "hgnc". To avoid confusion, it is strongly recommended to use the id_type parameter, especially for numeric ids.
Extracting Information About Many GenesIn addition to the detailed "card" view of individual genes, GeneCards provides two powerful tools for working with sets of genes, GeneAlaCart and GeneAnalytics:
|GeneALaCart accepts a list (batch) of gene symbols or identifiers, together with the user's selected data fields of interest (e.g. aliases, descriptions, proteins, disorders, publications, etc), and produces a tabulated file of annotations for the gene set. GeneALaCart is free for academic use but requires registration.|
GeneAnaLytics is available at http://geneanalytics.genecards.org
FAQFrequently Asked Questions
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