The following is a list of "hot" genes: those that have been most frequently requested at the GeneCards home site since Jan 1, 2009, sorted by frequency of access.

  1. EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  2. TUBA8 tubulin, alpha 8
  3. TP53 tumor protein p53
  4. PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
  5. JAK2 Janus kinase 2
  6. GAPDH glyceraldehyde-3-phosphate dehydrogenase
  7. BRCA1 breast cancer 1, early onset
  8. TUBE1 tubulin, epsilon 1
  9. ADD1 adducin 1 (alpha)
  10. HTT huntingtin
  11. BCL2 B-cell CLL/lymphoma 2
  12. MYC v-myc myelocytomatosis viral oncogene homolog (avian)
  13. HGF hepatocyte growth factor (hepapoietin A; scatter factor)
  14. GH1 growth hormone 1
  15. CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  16. BRAF v-raf murine sarcoma viral oncogene homolog B1
  17. ESR1 estrogen receptor 1
  18. BAX BCL2-associated X protein
  19. FUK fucokinase
  20. KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  21. KDR kinase insert domain receptor (a type III receptor tyrosine kinase)
  22. ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  23. ARNT aryl hydrocarbon receptor nuclear translocator
  24. PAX6 paired box 6
  25. PTEN phosphatase and tensin homolog
  26. CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
  27. DMD dystrophin
  28. GATA4 GATA binding protein 4
  29. TNF tumor necrosis factor (TNF superfamily, member 2)
  30. HBB hemoglobin, beta
  31. BRCA2 breast cancer 2, early onset
  32. APOE apolipoprotein E
  33. MTHFR 5,10-methylenetetrahydrofolate reductase (NADPH)
  34. CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
  35. WTAP Wilms tumor 1 associated protein
  36. TERT telomerase reverse transcriptase
  37. VEGFA vascular endothelial growth factor A
  38. PPARG peroxisome proliferator-activated receptor gamma
  39. ATM ataxia telangiectasia mutated
  40. PCNA proliferating cell nuclear antigen
  41. AKT1 v-akt murine thymoma viral oncogene homolog 1
  42. BDNF brain-derived neurotrophic factor
  43. RB1 retinoblastoma 1
  44. IL6 interleukin 6 (interferon, beta 2)
  45. CCND1 cyclin D1
  46. EGR1 early growth response 1
  47. ACTB actin, beta
  48. CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  49. RET ret proto-oncogene
  50. NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  51. NF1 neurofibromin 1
  52. GCK glucokinase (hexokinase 4)
  53. ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
  54. KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  55. SOD1 superoxide dismutase 1, soluble
  56. SIRT1 sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
  57. APC adenomatous polyposis coli
  58. CXCR4 chemokine (C-X-C motif) receptor 4
  59. IGF1 insulin-like growth factor 1 (somatomedin C)
  60. JUN jun oncogene
  61. AKT2 v-akt murine thymoma viral oncogene homolog 2
  62. CD44 CD44 molecule (Indian blood group)
  63. FOS FBJ murine osteosarcoma viral oncogene homolog
  64. CASP3 caspase 3, apoptosis-related cysteine peptidase
  65. MET met proto-oncogene (hepatocyte growth factor receptor)
  66. STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
  67. FOXP2 forkhead box P2
  68. FGFR3 fibroblast growth factor receptor 3
  69. NOS3 nitric oxide synthase 3 (endothelial cell)
  70. JUP junction plakoglobin
  71. G6PD glucose-6-phosphate dehydrogenase
  72. CDH1 cadherin 1, type 1, E-cadherin (epithelial)
  73. MDM2 Mdm2 p53 binding protein homolog (mouse)
  74. VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
  75. RUNX1 runt-related transcription factor 1
  76. SP1 Sp1 transcription factor
  77. RAF1 v-raf-1 murine leukemia viral oncogene homolog 1
  78. TGFB1 transforming growth factor, beta 1
  79. EP300 E1A binding protein p300
  80. MMP1 matrix metallopeptidase 1 (interstitial collagenase)
  81. CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
  82. PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide
  83. GATA5 GATA binding protein 5
  84. POU5F1 POU class 5 homeobox 1
  85. MAPK3 mitogen-activated protein kinase 3
  86. HPRT1 hypoxanthine phosphoribosyltransferase 1
  87. FGG fibrinogen gamma chain
  88. SOX2 SRY (sex determining region Y)-box 2
  89. ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  90. ABL1 c-abl oncogene 1, receptor tyrosine kinase
  91. HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  92. CCR5 chemokine (C-C motif) receptor 5
  93. AR androgen receptor
  94. HFE hemochromatosis
  95. SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  96. CCL2 chemokine (C-C motif) ligand 2
  97. MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  98. FOXP3 forkhead box P3
  99. PHB prohibitin
  100. SPP1 secreted phosphoprotein 1
  101. SMAD4 SMAD family member 4
  102. AIM2 absent in melanoma 2
  103. APP amyloid beta (A4) precursor protein
  104. PLAU plasminogen activator, urokinase
  105. IGF1R insulin-like growth factor 1 receptor
  106. BTK Bruton agammaglobulinemia tyrosine kinase
  107. MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  108. PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  109. EMP3 epithelial membrane protein 3
  110. COMT catechol-O-methyltransferase
  111. FN1 fibronectin 1
  112. WT1 Wilms tumor 1
  113. CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
  114. BCL2L1 BCL2-like 1
  115. MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
  116. INSR insulin receptor
  117. FOXA2 forkhead box A2
  118. SOX9 SRY (sex determining region Y)-box 9
  119. FGFR2 fibroblast growth factor receptor 2
  120. CASR calcium-sensing receptor
  121. SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  122. MBP myelin basic protein
  123. GBA glucosidase, beta; acid (includes glucosylceramidase)
  124. MAPK1 mitogen-activated protein kinase 1
  125. IL8 interleukin 8
  126. MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
  127. FAS Fas (TNF receptor superfamily, member 6)
  128. NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
  129. MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  130. COL1A1 collagen, type I, alpha 1
  131. IGF2 insulin-like growth factor 2 (somatomedin A)
  132. SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  133. FLT3 fms-related tyrosine kinase 3
  134. BMP2 bone morphogenetic protein 2
  135. NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  136. MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
  137. VIM vimentin
  138. GSK3B glycogen synthase kinase 3 beta
  139. PML promyelocytic leukemia
  140. IL1B interleukin 1, beta
  141. NRG1 neuregulin 1
  142. KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1
  143. SHH sonic hedgehog homolog (Drosophila)
  144. GSTM1 glutathione S-transferase mu 1
  145. STAT1 signal transducer and activator of transcription 1, 91kDa
  146. SCN1A sodium channel, voltage-gated, type I, alpha subunit
  147. FBN1 fibrillin 1
  148. PGR progesterone receptor
  149. BMI1 BMI1 polycomb ring finger oncogene
  150. NQO1 NAD(P)H dehydrogenase, quinone 1
  151. HEXA hexosaminidase A (alpha polypeptide)
  152. MAPT microtubule-associated protein tau
  153. E2F1 E2F transcription factor 1
  154. BMP4 bone morphogenetic protein 4
  155. MAOA monoamine oxidase A
  156. BIRC5 baculoviral IAP repeat-containing 5
  157. INS insulin
  158. MECP2 methyl CpG binding protein 2 (Rett syndrome)
  159. UBB ubiquitin B
  160. CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
  161. ADRB2 adrenergic, beta-2-, receptor, surface
  162. ICAM1 intercellular adhesion molecule 1
  163. NOTCH1 Notch homolog 1, translocation-associated (Drosophila)
  164. GATA1 GATA binding protein 1 (globin transcription factor 1)
  165. CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
  166. RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  167. HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
  168. CD34 CD34 molecule
  169. IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
  170. BCR breakpoint cluster region
  171. PAH phenylalanine hydroxylase
  172. MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  173. OTC ornithine carbamoyltransferase
  174. EPO erythropoietin
  175. LMNA lamin A/C
  176. MYB v-myb myeloblastosis viral oncogene homolog (avian)
  177. ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
  178. SRY sex determining region Y
  179. FASN fatty acid synthase
  180. NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  181. EGF epidermal growth factor (beta-urogastrone)
  182. PARP1 poly (ADP-ribose) polymerase 1
  183. HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  184. ALB albumin
  185. ASS1 argininosuccinate synthetase 1
  186. CD14 CD14 molecule
  187. FGFR1 fibroblast growth factor receptor 1
  188. FUS fused in sarcoma
  189. IL10 interleukin 10
  190. CREBBP CREB binding protein
  191. TLR4 toll-like receptor 4
  192. PDGFRA platelet-derived growth factor receptor, alpha polypeptide
  193. SOD2 superoxide dismutase 2, mitochondrial
  194. ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2
  195. LDLR low density lipoprotein receptor
  196. KLF4 Kruppel-like factor 4 (gut)
  197. LPL lipoprotein lipase
  198. CLU clusterin
  199. FOXO1 forkhead box O1
  200. ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
  201. PRNP prion protein
  202. TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
  203. CDK2 cyclin-dependent kinase 2
  204. DDR1 discoidin domain receptor tyrosine kinase 1
  205. LOX lysyl oxidase
  206. AIRE autoimmune regulator
  207. SMAD3 SMAD family member 3
  208. EZH2 enhancer of zeste homolog 2 (Drosophila)
  209. NGLY1 N-glycanase 1
  210. VHL von Hippel-Lindau tumor suppressor
  211. SMAD7 SMAD family member 7
  212. SMAD2 SMAD family member 2
  213. GSTP1 glutathione S-transferase pi 1
  214. ERCC1 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
  215. JAK1 Janus kinase 1
  216. GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
  217. MCL1 myeloid cell leukemia sequence 1 (BCL2-related)
  218. PAPPA pregnancy-associated plasma protein A, pappalysin 1
  219. GATA3 GATA binding protein 3
  220. HNF4A hepatocyte nuclear factor 4, alpha
  221. TCF4 transcription factor 4
  222. FYN FYN oncogene related to SRC, FGR, YES
  223. SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  224. CD4 CD4 molecule
  225. IL2 interleukin 2
  226. FMR1 fragile X mental retardation 1
  227. NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
  228. DRD2 dopamine receptor D2
  229. RUNX2 runt-related transcription factor 2
  230. TGFBI transforming growth factor, beta-induced, 68kDa
  231. CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
  232. FTO fat mass and obesity associated
  233. RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
  234. SNCA synuclein, alpha (non A4 component of amyloid precursor)
  235. UTY ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
  236. CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  237. PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  238. B2M beta-2-microglobulin
  239. FGF2 fibroblast growth factor 2 (basic)
  240. BAD BCL2-associated agonist of cell death
  241. TBP TATA box binding protein
  242. NLK nemo-like kinase
  243. TWIST1 twist homolog 1 (Drosophila)
  244. A2M alpha-2-macroglobulin
  245. WRN Werner syndrome, RecQ helicase-like
  246. GNAS GNAS complex locus
  247. MSH6 mutS homolog 6 (E. coli)
  248. APOA1 apolipoprotein A-I
  249. MGMT O-6-methylguanine-DNA methyltransferase
  250. ALK anaplastic lymphoma receptor tyrosine kinase
  251. AURKA aurora kinase A
  252. FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  253. USF1 upstream transcription factor 1
  254. PPARA peroxisome proliferator-activated receptor alpha
  255. CD36 CD36 molecule (thrombospondin receptor)
  256. BLM Bloom syndrome, RecQ helicase-like
  257. NTRK1 neurotrophic tyrosine kinase, receptor, type 1
  258. CD68 CD68 molecule
  259. CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
  260. SYK spleen tyrosine kinase
  261. GFAP glial fibrillary acidic protein
  262. TP63 tumor protein p63
  263. YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
  264. NA neurocanthocytosis
  265. BCL6 B-cell CLL/lymphoma 6
  266. LEPR leptin receptor
  267. SPEN spen homolog, transcriptional regulator (Drosophila)
  268. MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
  269. IGFBP3 insulin-like growth factor binding protein 3
  270. PTPRC protein tyrosine phosphatase, receptor type, C
  271. IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor)
  272. NOD2 nucleotide-binding oligomerization domain containing 2
  273. LEP leptin
  274. F2 coagulation factor II (thrombin)
  275. CDK4 cyclin-dependent kinase 4
  276. CREB1 cAMP responsive element binding protein 1
  277. CAT catalase
  278. LEF1 lymphoid enhancer-binding factor 1
  279. CD24 CD24 molecule
  280. TNFAIP3 tumor necrosis factor, alpha-induced protein 3
  281. MPO myeloperoxidase
  282. PTPN11 protein tyrosine phosphatase, non-receptor type 11
  283. NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
  284. CRP C-reactive protein, pentraxin-related
  285. JAK3 Janus kinase 3
  286. HN1 hematological and neurological expressed 1
  287. IFNG interferon, gamma
  288. MAPK14 mitogen-activated protein kinase 14
  289. MUC1 mucin 1, cell surface associated
  290. AGTR1 angiotensin II receptor, type 1
  291. HMGB1 high-mobility group box 1
  292. PARK2 Parkinson disease (autosomal recessive, juvenile) 2, parkin
  293. AVPR1A arginine vasopressin receptor 1A
  294. CCL5 chemokine (C-C motif) ligand 5
  295. IRS1 insulin receptor substrate 1
  296. FOXO3 forkhead box O3
  297. TOP2A topoisomerase (DNA) II alpha 170kDa
  298. CAV1 caveolin 1, caveolae protein, 22kDa
  299. UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
  300. ATP7B ATPase, Cu++ transporting, beta polypeptide
  301. TTR transthyretin
  302. HMGA2 high mobility group AT-hook 2
  303. POMC proopiomelanocortin
  304. F8 coagulation factor VIII, procoagulant component
  305. EPHB4 EPH receptor B4
  306. MYH9 myosin, heavy chain 9, non-muscle
  307. HBA1 hemoglobin, alpha 1
  308. TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
  309. TYR tyrosinase (oculocutaneous albinism IA)
  310. NOS2 nitric oxide synthase 2, inducible
  311. GRB2 growth factor receptor-bound protein 2
  312. DKK1 dickkopf homolog 1 (Xenopus laevis)
  313. ADIPOQ adiponectin, C1Q and collagen domain containing
  314. GATA6 GATA binding protein 6
  315. ZEB1 zinc finger E-box binding homeobox 1
  316. LIF leukemia inhibitory factor (cholinergic differentiation factor)
  317. HAGH hydroxyacylglutathione hydrolase
  318. ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
  319. SELE selectin E
  320. RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
  321. STK11 serine/threonine kinase 11
  322. DNMT1 DNA (cytosine-5-)-methyltransferase 1
  323. TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
  324. CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  325. ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
  326. XIAP X-linked inhibitor of apoptosis
  327. CAMK2G calcium/calmodulin-dependent protein kinase II gamma
  328. ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
  329. RORA RAR-related orphan receptor A
  330. HDAC1 histone deacetylase 1
  331. MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
  332. PTK2 PTK2 protein tyrosine kinase 2
  333. SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
  334. ETS1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
  335. TIMP3 TIMP metallopeptidase inhibitor 3
  336. ESR2 estrogen receptor 2 (ER beta)
  337. CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
  338. RARA retinoic acid receptor, alpha
  339. MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
  340. ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  341. TIMP1 TIMP metallopeptidase inhibitor 1
  342. ANXA1 annexin A1
  343. CASP8 caspase 8, apoptosis-related cysteine peptidase
  344. CSF1R colony stimulating factor 1 receptor
  345. NANOG Nanog homeobox
  346. UNG uracil-DNA glycosylase
  347. WNT5A wingless-type MMTV integration site family, member 5A
  348. TOP1 topoisomerase (DNA) I
  349. TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
  350. PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
  351. CTGF connective tissue growth factor
  352. CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
  353. DRD4 dopamine receptor D4
  354. MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
  355. APOB apolipoprotein B (including Ag(x) antigen)
  356. FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  357. NGFR nerve growth factor receptor (TNFR superfamily, member 16)
  358. MEN1 multiple endocrine neoplasia I
  359. HDGF hepatoma-derived growth factor (high-mobility group protein 1-like)
  360. FH fumarate hydratase
  361. TET2 tet oncogene family member 2
  362. CHUK conserved helix-loop-helix ubiquitous kinase
  363. ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
  364. PTCH1 patched homolog 1 (Drosophila)
  365. MAPK8 mitogen-activated protein kinase 8
  366. TGFBR1 transforming growth factor, beta receptor 1
  367. MSX1 msh homeobox 1
  368. L1CAM L1 cell adhesion molecule
  369. SPARC secreted protein, acidic, cysteine-rich (osteonectin)
  370. PPIA peptidylprolyl isomerase A (cyclophilin A)
  371. ALDH1A1 aldehyde dehydrogenase 1 family, member A1
  372. GSN gelsolin (amyloidosis, Finnish type)
  373. MTOR mechanistic target of rapamycin (serine/threonine kinase)
  374. CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
  375. OTX2 orthodenticle homeobox 2
  376. PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  377. NOTCH3 Notch homolog 3 (Drosophila)
  378. PGK1 phosphoglycerate kinase 1
  379. SCN5A sodium channel, voltage-gated, type V, alpha subunit
  380. TSC2 tuberous sclerosis 2
  381. CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
  382. TF transferrin
  383. TPO thyroid peroxidase
  384. CD40 CD40 molecule, TNF receptor superfamily member 5
  385. CD19 CD19 molecule
  386. UBE3A ubiquitin protein ligase E3A
  387. PDGFRB platelet-derived growth factor receptor, beta polypeptide
  388. MME membrane metallo-endopeptidase
  389. HLA-B major histocompatibility complex, class I, B
  390. DHFR dihydrofolate reductase
  391. HNF1A HNF1 homeobox A
  392. EPOR erythropoietin receptor
  393. WNT1 wingless-type MMTV integration site family, member 1
  394. BLNK B-cell linker
  395. SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  396. NF2 neurofibromin 2 (merlin)
  397. CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
  398. TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
  399. HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
  400. PSEN1 presenilin 1
  401. CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
  402. HBA2 hemoglobin, alpha 2
  403. CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  404. HMOX1 heme oxygenase (decycling) 1
  405. PLAT plasminogen activator, tissue
  406. SQSTM1 sequestosome 1
  407. KCNH2 potassium voltage-gated channel, subfamily H (eag-related), member 2
  408. HLA-G major histocompatibility complex, class I, G
  409. CXCL10 chemokine (C-X-C motif) ligand 10
  410. CTLA4 cytotoxic T-lymphocyte-associated protein 4
  411. DICER1 dicer 1, ribonuclease type III
  412. GHR growth hormone receptor
  413. JAG1 jagged 1 (Alagille syndrome)
  414. ALOX5 arachidonate 5-lipoxygenase
  415. FOXA1 forkhead box A1
  416. TLR2 toll-like receptor 2
  417. ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  418. ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  419. CDC42 cell division cycle 42 (GTP binding protein, 25kDa)
  420. NTRK2 neurotrophic tyrosine kinase, receptor, type 2
  421. AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  422. EEF1A1 eukaryotic translation elongation factor 1 alpha 1
  423. DDIT3 DNA-damage-inducible transcript 3
  424. SGK1 serum/glucocorticoid regulated kinase 1
  425. VCAM1 vascular cell adhesion molecule 1
  426. CDK5 cyclin-dependent kinase 5
  427. NLRP3 NLR family, pyrin domain containing 3
  428. MITF microphthalmia-associated transcription factor
  429. PON1 paraoxonase 1
  430. CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  431. ENO1 enolase 1, (alpha)
  432. ADA adenosine deaminase
  433. FGA fibrinogen alpha chain
  434. CSF1 colony stimulating factor 1 (macrophage)
  435. MUSK muscle, skeletal, receptor tyrosine kinase
  436. VWF von Willebrand factor
  437. VKORC1 vitamin K epoxide reductase complex, subunit 1
  438. ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
  439. GATA2 GATA binding protein 2
  440. NGF nerve growth factor (beta polypeptide)
  441. PRKCA protein kinase C, alpha
  442. OPRM1 opioid receptor, mu 1
  443. GSTT1 glutathione S-transferase theta 1
  444. LTA lymphotoxin alpha (TNF superfamily, member 1)
  445. ARSA arylsulfatase A
  446. IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  447. ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
  448. IL4 interleukin 4
  449. AHR aryl hydrocarbon receptor
  450. LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  451. NR4A2 nuclear receptor subfamily 4, group A, member 2
  452. CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
  453. FER fer (fps/fes related) tyrosine kinase
  454. UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  455. A2BP1
  456. WWOX WW domain containing oxidoreductase
  457. SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
  458. ATF3 activating transcription factor 3
  459. PRKDC protein kinase, DNA-activated, catalytic polypeptide
  460. DHCR7 7-dehydrocholesterol reductase
  461. DISC1 disrupted in schizophrenia 1
  462. PLK1 polo-like kinase 1 (Drosophila)
  463. THY1 Thy-1 cell surface antigen
  464. MYD88 myeloid differentiation primary response gene (88)
  465. LGR5 leucine-rich repeat-containing G protein-coupled receptor 5
  466. MBS3 Moebius syndrome 3
  467. JUNB jun B proto-oncogene
  468. HSPA1A heat shock 70kDa protein 1A
  469. HSPA8 heat shock 70kDa protein 8
  470. FABP4 fatty acid binding protein 4, adipocyte
  471. CCR7 chemokine (C-C motif) receptor 7
  472. RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
  473. GADD45A growth arrest and DNA-damage-inducible, alpha
  474. ACTA1 actin, alpha 1, skeletal muscle
  475. BIRC3 baculoviral IAP repeat-containing 3
  476. ACACA acetyl-Coenzyme A carboxylase alpha
  477. GIF gastric intrinsic factor (vitamin B synthesis)
  478. DPP4 dipeptidyl-peptidase 4
  479. LCK lymphocyte-specific protein tyrosine kinase
  480. RHOA ras homolog gene family, member A
  481. MYOD1 myogenic differentiation 1
  482. BCL2L11 BCL2-like 11 (apoptosis facilitator)
  483. ACHE acetylcholinesterase (Yt blood group)
  484. ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  485. WHSC1 Wolf-Hirschhorn syndrome candidate 1
  486. THBS1 thrombospondin 1
  487. HDAC2 histone deacetylase 2
  488. BBC3 BCL2 binding component 3
  489. CHEK2 CHK2 checkpoint homolog (S. pombe)
  490. FLNA filamin A, alpha
  491. PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
  492. FANCA Fanconi anemia, complementation group A
  493. GAL galanin prepropeptide
  494. MYH7 myosin, heavy chain 7, cardiac muscle, beta
  495. SOCS3 suppressor of cytokine signaling 3
  496. HLA-DRB1 major histocompatibility complex, class II, DR beta 1
  497. POLG polymerase (DNA directed), gamma
  498. HGD homogentisate 1,2-dioxygenase (homogentisate oxidase)
  499. HES1 hairy and enhancer of split 1, (Drosophila)
  500. TFRC transferrin receptor (p90, CD71)



Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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