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GeneCards® Hot Genes

The following is a list of "hot" genes: those that have been most frequently requested at the GeneCards home site since Dec 21, 2007 sorted by frequency of access.

  1. EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  2. SORT1 sortilin 1
  3. TP53 tumor protein p53
  4. BRCA1 breast cancer 1, early onset
  5. CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  6. VIM vimentin
  7. INSR insulin receptor
  8. HGF hepatocyte growth factor (hepapoietin A; scatter factor)
  9. EPHB4 EPH receptor B4
  10. BRCA2 breast cancer 2, early onset
  11. NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  12. BCL2 B-cell CLL/lymphoma 2
  13. ESR1 estrogen receptor 1
  14. EP300 E1A binding protein p300
  15. JAK2 Janus kinase 2 (a protein tyrosine kinase)
  16. PCNA proliferating cell nuclear antigen
  17. ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  18. AKT1 v-akt murine thymoma viral oncogene homolog 1
  19. PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
  20. CREBBP CREB binding protein (Rubinstein-Taybi syndrome)
  21. NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  22. HTT huntingtin
  23. PTEN phosphatase and tensin homolog
  24. AR androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
  25. FGF2 fibroblast growth factor 2 (basic)
  26. VEGFA vascular endothelial growth factor A
  27. ATM ataxia telangiectasia mutated
  28. ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
  29. GAPDH glyceraldehyde-3-phosphate dehydrogenase
  30. PSAP prosaposin
  31. PARP1 poly (ADP-ribose) polymerase 1
  32. HEXB hexosaminidase B (beta polypeptide)
  33. MTHFR 5,10-methylenetetrahydrofolate reductase (NADPH)
  34. STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
  35. APOE apolipoprotein E
  36. ADRB2 adrenergic, beta-2-, receptor, surface
  37. ABL1 c-abl oncogene 1, receptor tyrosine kinase
  38. RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  39. CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
  40. HIF1A hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  41. ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
  42. TUBA8 tubulin, alpha 8
  43. MAPK8 mitogen-activated protein kinase 8
  44. DMD dystrophin (muscular dystrophy, Duchenne and Becker types)
  45. TNF tumor necrosis factor (TNF superfamily, member 2)
  46. HBB hemoglobin, beta
  47. HFE hemochromatosis
  48. KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  49. PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  50. APP amyloid beta (A4) precursor protein
  51. HEXA hexosaminidase A (alpha polypeptide)
  52. RB1 retinoblastoma 1
  53. IL6 interleukin 6 (interferon, beta 2)
  54. SOD1 superoxide dismutase 1, soluble
  55. MYC v-myc myelocytomatosis viral oncogene homolog (avian)
  56. TOP2A topoisomerase (DNA) II alpha 170kDa
  57. FYN FYN oncogene related to SRC, FGR, YES
  58. ACHE acetylcholinesterase (Yt blood group)
  59. NR4A2 nuclear receptor subfamily 4, group A, member 2
  60. TUBE1 tubulin, epsilon 1
  61. MAPK1 mitogen-activated protein kinase 1
  62. ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
  63. MAPK9 mitogen-activated protein kinase 9
  64. SNAI2 snail homolog 2 (Drosophila)
  65. BRAF v-raf murine sarcoma viral oncogene homolog B1
  66. BTK Bruton agammaglobulinemia tyrosine kinase
  67. IGF1 insulin-like growth factor 1 (somatomedin C)
  68. PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide
  69. MDM2 Mdm2 p53 binding protein homolog (mouse)
  70. MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  71. BCL2L1 BCL2-like 1
  72. BLM Bloom syndrome
  73. CCND1 cyclin D1
  74. CDH1 cadherin 1, type 1, E-cadherin (epithelial)
  75. CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
  76. MSN moesin
  77. CASP9 caspase 9, apoptosis-related cysteine peptidase
  78. APC adenomatous polyposis coli
  79. TGFB1 transforming growth factor, beta 1
  80. CD4 CD4 molecule
  81. BDNF brain-derived neurotrophic factor
  82. GRB2 growth factor receptor-bound protein 2
  83. ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  84. SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  85. ATP7B ATPase, Cu++ transporting, beta polypeptide
  86. VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
  87. CCR5 chemokine (C-C motif) receptor 5
  88. ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
  89. ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  90. NOS2A nitric oxide synthase 2A (inducible, hepatocytes)
  91. CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
  92. ICAM1 intercellular adhesion molecule 1
  93. BAX BCL2-associated X protein
  94. INS insulin
  95. CDC2 cell division cycle 2, G1 to S and G2 to M
  96. ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  97. NTRK1 neurotrophic tyrosine kinase, receptor, type 1
  98. E2F1 E2F transcription factor 1
  99. MET met proto-oncogene (hepatocyte growth factor receptor)
  100. PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
  101. JUN jun oncogene
  102. MAPK14 mitogen-activated protein kinase 14
  103. MAPK3 mitogen-activated protein kinase 3
  104. GBA glucosidase, beta; acid (includes glucosylceramidase)
  105. PPARG peroxisome proliferator-activated receptor gamma
  106. ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  107. CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  108. ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
  109. MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  110. PSEN1 presenilin 1
  111. A2M alpha-2-macroglobulin
  112. FMR1 fragile X mental retardation 1
  113. CASP3 caspase 3, apoptosis-related cysteine peptidase
  114. VWF von Willebrand factor
  115. CDK4 cyclin-dependent kinase 4
  116. JAK3 Janus kinase 3 (a protein tyrosine kinase, leukocyte)
  117. FOS v-fos FBJ murine osteosarcoma viral oncogene homolog
  118. RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
  119. ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  120. BAD BCL2-antagonist of cell death
  121. EGF epidermal growth factor (beta-urogastrone)
  122. CYCS cytochrome c, somatic
  123. SP1 Sp1 transcription factor
  124. IL1B interleukin 1, beta
  125. ARNT aryl hydrocarbon receptor nuclear translocator
  126. HNF4A hepatocyte nuclear factor 4, alpha
  127. GSTM1 glutathione S-transferase M1
  128. RET ret proto-oncogene
  129. LPL lipoprotein lipase
  130. GSTT1 glutathione S-transferase theta 1
  131. NOS1 nitric oxide synthase 1 (neuronal)
  132. NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
  133. PLAU plasminogen activator, urokinase
  134. PML promyelocytic leukemia
  135. LEP leptin
  136. WTAP Wilms tumor 1 associated protein
  137. BMP4 bone morphogenetic protein 4
  138. CASP8 caspase 8, apoptosis-related cysteine peptidase
  139. FGFR1 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  140. BLNK B-cell linker
  141. GSTP1 glutathione S-transferase pi 1
  142. IL2 interleukin 2
  143. FAS Fas (TNF receptor superfamily, member 6)
  144. STAT1 signal transducer and activator of transcription 1, 91kDa
  145. CREB1 cAMP responsive element binding protein 1
  146. GJA1 gap junction protein, alpha 1, 43kDa
  147. SREBF1 sterol regulatory element binding transcription factor 1
  148. G6PD glucose-6-phosphate dehydrogenase
  149. CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
  150. ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
  151. PRNP prion protein
  152. ACTB actin, beta
  153. SMAD4 SMAD family member 4
  154. BCR breakpoint cluster region
  155. KDR kinase insert domain receptor (a type III receptor tyrosine kinase)
  156. MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
  157. NOS3 nitric oxide synthase 3 (endothelial cell)
  158. HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  159. NF1 neurofibromin 1
  160. ATP7A ATPase, Cu++ transporting, alpha polypeptide
  161. CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
  162. CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence
  163. CHUK conserved helix-loop-helix ubiquitous kinase
  164. CHRM1 cholinergic receptor, muscarinic 1
  165. HDAC1 histone deacetylase 1
  166. CXCR4 chemokine (C-X-C motif) receptor 4
  167. PTPRC protein tyrosine phosphatase, receptor type, C
  168. ERCC1 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
  169. FGFR3 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
  170. COMT catechol-O-methyltransferase
  171. SOD2 superoxide dismutase 2, mitochondrial
  172. SHC1 SHC (Src homology 2 domain containing) transforming protein 1
  173. FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  174. FBN1 fibrillin 1
  175. RARA retinoic acid receptor, alpha
  176. LDLR low density lipoprotein receptor (familial hypercholesterolemia)
  177. GHR growth hormone receptor
  178. C3 complement component 3
  179. ESR2 estrogen receptor 2 (ER beta)
  180. WNT1 wingless-type MMTV integration site family, member 1
  181. GCK glucokinase (hexokinase 4)
  182. PAX6 paired box 6
  183. TPI1 triosephosphate isomerase 1
  184. WRN Werner syndrome
  185. ARSA arylsulfatase A
  186. PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  187. KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  188. BIRC5 baculoviral IAP repeat-containing 5 (survivin)
  189. SHH sonic hedgehog homolog (Drosophila)
  190. NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
  191. COL1A1 collagen, type I, alpha 1
  192. DRD2 dopamine receptor D2
  193. HMOX1 heme oxygenase (decycling) 1
  194. EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
  195. PRKCA protein kinase C, alpha
  196. GSK3B glycogen synthase kinase 3 beta
  197. NGFR nerve growth factor receptor (TNFR superfamily, member 16)
  198. ATF4 activating transcription factor 4 (tax-responsive enhancer element B67)
  199. RAF1 v-raf-1 murine leukemia viral oncogene homolog 1
  200. MPO myeloperoxidase
  201. AKT2 v-akt murine thymoma viral oncogene homolog 2
  202. ACADM acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
  203. LEPR leptin receptor
  204. EGR1 early growth response 1
  205. IL8 interleukin 8
  206. EMP3 epithelial membrane protein 3
  207. RHOA ras homolog gene family, member A
  208. CCL2 chemokine (C-C motif) ligand 2
  209. MAP2K1 mitogen-activated protein kinase kinase 1
  210. AOC3 amine oxidase, copper containing 3 (vascular adhesion protein 1)
  211. FUK fucokinase
  212. PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  213. HNF1A HNF1 homeobox A
  214. IFNG interferon, gamma
  215. CD44 CD44 molecule (Indian blood group)
  216. CHEK2 CHK2 checkpoint homolog (S. pombe)
  217. SQSTM1 sequestosome 1
  218. VHL von Hippel-Lindau tumor suppressor
  219. RUNX1 runt-related transcription factor 1
  220. SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  221. IGF1R insulin-like growth factor 1 receptor
  222. NQO1 NAD(P)H dehydrogenase, quinone 1
  223. SMAD3 SMAD family member 3
  224. CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
  225. PDGFRA platelet-derived growth factor receptor, alpha polypeptide
  226. CDC42 cell division cycle 42 (GTP binding protein, 25kDa)
  227. JAK1 Janus kinase 1 (a protein tyrosine kinase)
  228. APOD apolipoprotein D
  229. PRKCG protein kinase C, gamma
  230. TERT telomerase reverse transcriptase
  231. THBS1 thrombospondin 1
  232. CASR calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
  233. TUBB tubulin, beta
  234. CDK2 cyclin-dependent kinase 2
  235. VCP valosin-containing protein
  236. MLL myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
  237. MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
  238. ADIPOQ adiponectin, C1Q and collagen domain containing
  239. IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  240. ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
  241. FLNB filamin B, beta (actin binding protein 278)
  242. TBP TATA box binding protein
  243. ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
  244. GLA galactosidase, alpha
  245. CLU clusterin
  246. PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
  247. CDK5 cyclin-dependent kinase 5
  248. TOP1 topoisomerase (DNA) I
  249. NTRK2 neurotrophic tyrosine kinase, receptor, type 2
  250. FASLG Fas ligand (TNF superfamily, member 6)
  251. AGER advanced glycosylation end product-specific receptor
  252. PTPN11 protein tyrosine phosphatase, non-receptor type 11
  253. LCK lymphocyte-specific protein tyrosine kinase
  254. MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  255. FGFR2 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
  256. GSN gelsolin (amyloidosis, Finnish type)
  257. TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
  258. ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  259. CHRNA7 cholinergic receptor, nicotinic, alpha 7
  260. TYR tyrosinase (oculocutaneous albinism IA)
  261. CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
  262. ADORA1 adenosine A1 receptor
  263. MYP2 myopia 2 (high grade, autosomal dominant)
  264. NOTCH1 Notch homolog 1, translocation-associated (Drosophila)
  265. PRKG1 protein kinase, cGMP-dependent, type I
  266. ACTA1 actin, alpha 1, skeletal muscle
  267. GNAS GNAS complex locus
  268. TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
  269. CTSD cathepsin D
  270. TH tyrosine hydroxylase
  271. ACTN4 actinin, alpha 4
  272. FN1 fibronectin 1
  273. CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  274. CHAT choline acetyltransferase
  275. CP ceruloplasmin (ferroxidase)
  276. UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  277. SYK spleen tyrosine kinase
  278. IL8RB interleukin 8 receptor, beta
  279. CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
  280. TLR4 toll-like receptor 4
  281. MGMT O-6-methylguanine-DNA methyltransferase
  282. WNT5A wingless-type MMTV integration site family, member 5A
  283. LIPA lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
  284. HLA-B major histocompatibility complex, class I, B
  285. CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
  286. CAV1 caveolin 1, caveolae protein, 22kDa
  287. HMGB1 high-mobility group box 1
  288. CSF3 colony stimulating factor 3 (granulocyte)
  289. ALB albumin
  290. DMPK dystrophia myotonica-protein kinase
  291. EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
  292. WNT2 wingless-type MMTV integration site family member 2
  293. DCN decorin
  294. ASS1 argininosuccinate synthetase 1
  295. ERCC2 excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
  296. ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  297. FRAP1 FK506 binding protein 12-rapamycin associated protein 1
  298. ADORA2A adenosine A2a receptor
  299. LRP1 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
  300. PTGDS prostaglandin D2 synthase 21kDa (brain)
  301. ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
  302. APOA1 apolipoprotein A-I
  303. WT1 Wilms tumor 1
  304. MECP2 methyl CpG binding protein 2 (Rett syndrome)
  305. IL1A interleukin 1, alpha
  306. PGR progesterone receptor
  307. SELP selectin P (granule membrane protein 140kDa, antigen CD62)
  308. NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  309. EPO erythropoietin
  310. ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
  311. AGTR1 angiotensin II receptor, type 1
  312. DPP4 dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)
  313. PC pyruvate carboxylase
  314. HPRT1 hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)
  315. CD14 CD14 molecule
  316. P4HB procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
  317. ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
  318. SLC6A2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  319. ADRB3 adrenergic, beta-3-, receptor
  320. TTR transthyretin
  321. TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
  322. PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  323. CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  324. CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
  325. LTA lymphotoxin alpha (TNF superfamily, member 1)
  326. GAL galanin prepropeptide
  327. TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  328. ACTG1 actin, gamma 1
  329. VAV1 vav 1 guanine nucleotide exchange factor
  330. RYR1 ryanodine receptor 1 (skeletal)
  331. FASN fatty acid synthase
  332. HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
  333. PDGFRB platelet-derived growth factor receptor, beta polypeptide
  334. BMP2 bone morphogenetic protein 2
  335. NBN nibrin
  336. SOX9 SRY (sex determining region Y)-box 9
  337. TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
  338. SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  339. MAPT microtubule-associated protein tau
  340. GFAP glial fibrillary acidic protein
  341. TGFB3 transforming growth factor, beta 3
  342. ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
  343. CCR2 chemokine (C-C motif) receptor 2
  344. GSR glutathione reductase
  345. ALK anaplastic lymphoma receptor tyrosine kinase
  346. HADHA hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
  347. IRS1 insulin receptor substrate 1
  348. ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  349. NCAM1 neural cell adhesion molecule 1
  350. FLT3 fms-related tyrosine kinase 3
  351. PPARA peroxisome proliferator-activated receptor alpha
  352. GALK1 galactokinase 1
  353. TAZ tafazzin
  354. GRN granulin
  355. SMAD2 SMAD family member 2
  356. ADRB1 adrenergic, beta-1-, receptor
  357. MAOA monoamine oxidase A
  358. MSH6 mutS homolog 6 (E. coli)
  359. PBX1 pre-B-cell leukemia homeobox 1
  360. AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
  361. NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
  362. PARK7 Parkinson disease (autosomal recessive, early onset) 7
  363. NRG1 neuregulin 1
  364. NR3C2 nuclear receptor subfamily 3, group C, member 2
  365. NEFL neurofilament, light polypeptide 68kDa
  366. CAT catalase
  367. ABAT 4-aminobutyrate aminotransferase
  368. CD40 CD40 molecule, TNF receptor superfamily member 5
  369. CHEK1 CHK1 checkpoint homolog (S. pombe)
  370. YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
  371. PARK2 Parkinson disease (autosomal recessive, juvenile) 2, parkin
  372. FADD Fas (TNFRSF6)-associated via death domain
  373. KLF6 Kruppel-like factor 6
  374. F7 coagulation factor VII (serum prothrombin conversion accelerator)
  375. APOB apolipoprotein B (including Ag(x) antigen)
  376. ATR ataxia telangiectasia and Rad3 related
  377. XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
  378. CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  379. LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  380. USF1 upstream transcription factor 1
  381. MAP3K1 mitogen-activated protein kinase kinase kinase 1
  382. TLR2 toll-like receptor 2
  383. ADAM17 ADAM metallopeptidase domain 17
  384. SELL selectin L
  385. AIRE autoimmune regulator
  386. SELE selectin E
  387. CRH corticotropin releasing hormone
  388. ACACA acetyl-Coenzyme A carboxylase alpha
  389. IL10 interleukin 10
  390. CASP7 caspase 7, apoptosis-related cysteine peptidase
  391. HDAC9 histone deacetylase 9
  392. LIF leukemia inhibitory factor (cholinergic differentiation factor)
  393. CALR calreticulin
  394. ALOX5 arachidonate 5-lipoxygenase
  395. MME membrane metallo-endopeptidase
  396. SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
  397. HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
  398. ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6
  399. ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
  400. SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  401. CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
  402. JAG1 jagged 1 (Alagille syndrome)
  403. BDKRB2 bradykinin receptor B2
  404. GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  405. ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2
  406. UBB ubiquitin B
  407. CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
  408. HLA-G major histocompatibility complex, class I, G
  409. ALDH1A1 aldehyde dehydrogenase 1 family, member A1
  410. ALS2 amyotrophic lateral sclerosis 2 (juvenile)
  411. ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  412. FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
  413. B2M beta-2-microglobulin
  414. CAMK2G calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
  415. A1BG alpha-1-B glycoprotein
  416. LRRK2 leucine-rich repeat kinase 2
  417. ELN elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)
  418. CEBPB CCAAT/enhancer binding protein (C/EBP), beta
  419. HSPA4 heat shock 70kDa protein 4
  420. SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
  421. THRA thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
  422. GRIA2 glutamate receptor, ionotropic, AMPA 2
  423. HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
  424. ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  425. MEF2A myocyte enhancer factor 2A
  426. IGF2 insulin-like growth factor 2 (somatomedin A)
  427. AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  428. AURKA aurora kinase A
  429. GADD45A growth arrest and DNA-damage-inducible, alpha
  430. F2 coagulation factor II (thrombin)
  431. JUP junction plakoglobin
  432. SCARB1 scavenger receptor class B, member 1
  433. ADRA2A adrenergic, alpha-2A-, receptor
  434. IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  435. LAMP1 lysosomal-associated membrane protein 1
  436. KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1
  437. ENO1 enolase 1, (alpha)
  438. TF transferrin
  439. DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
  440. CRYAB crystallin, alpha B
  441. LMNA lamin A/C
  442. ACP1 acid phosphatase 1, soluble
  443. NPY neuropeptide Y
  444. TGFBR1 transforming growth factor, beta receptor 1
  445. ATXN1 ataxin 1
  446. SIRT1 sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
  447. S100A1 S100 calcium binding protein A1
  448. WNT4 wingless-type MMTV integration site family, member 4
  449. HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
  450. NOD2 nucleotide-binding oligomerization domain containing 2
  451. RXRA retinoid X receptor, alpha
  452. SHBG sex hormone-binding globulin
  453. TXN thioredoxin
  454. AVPR2 arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)
  455. PSEN2 presenilin 2 (Alzheimer disease 4)
  456. KCNH2 potassium voltage-gated channel, subfamily H (eag-related), member 2
  457. LCT lactase
  458. COL2A1 collagen, type II, alpha 1
  459. GATA4 GATA binding protein 4
  460. OPRM1 opioid receptor, mu 1
  461. ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
  462. IRF1 interferon regulatory factor 1
  463. CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  464. SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  465. PECAM1 platelet/endothelial cell adhesion molecule
  466. SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
  467. HTR2A 5-hydroxytryptamine (serotonin) receptor 2A
  468. CD59 CD59 molecule, complement regulatory protein
  469. CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
  470. MMP1 matrix metallopeptidase 1 (interstitial collagenase)
  471. BCHE butyrylcholinesterase
  472. OGG1 8-oxoguanine DNA glycosylase
  473. RHO rhodopsin
  474. TIMP1 TIMP metallopeptidase inhibitor 1
  475. PHB prohibitin
  476. ANXA2 annexin A2
  477. MYH7 myosin, heavy chain 7, cardiac muscle, beta
  478. CRP C-reactive protein, pentraxin-related
  479. FGF1 fibroblast growth factor 1 (acidic)
  480. GUSB glucuronidase, beta
  481. TPP1 tripeptidyl peptidase I
  482. CCL5 chemokine (C-C motif) ligand 5
  483. WNT3A wingless-type MMTV integration site family, member 3A
  484. CETP cholesteryl ester transfer protein, plasma
  485. GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
  486. MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
  487. HDAC2 histone deacetylase 2
  488. FOXO3 forkhead box O3
  489. BAIAP2 BAI1-associated protein 2
  490. ASPA aspartoacylase (Canavan disease)
  491. MAPK10 mitogen-activated protein kinase 10
  492. FXN frataxin
  493. SFN stratifin
  494. ARAF v-raf murine sarcoma 3611 viral oncogene homolog
  495. PON1 paraoxonase 1
  496. RPS27A ribosomal protein S27a
  497. STAT5A signal transducer and activator of transcription 5A
  498. PAH phenylalanine hydroxylase
  499. AHSG alpha-2-HS-glycoprotein
  500. HSPB1 heat shock 27kDa protein 1