FLAD1 Gene
protein-coding GIFtS: 56
GCID: GC01P154955
|
|
FAD1 flavin adenine dinucleotide synthetase homolog (S....(Previous names: Fad1, flavin adenine dinucleotide synthetase, homolog (yeast)...)
| |
Aliases for FLAD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| FAD1 Flavin Adenine Dinucleotide Synthetase Homolog (S. Cerevisiae)1 2 | | Fad1, Flavin Adenine Dinucleotide Synthetase, Homolog (Yeast)1 | | FAD11 2 | | FAD-Synthetase1 | | Flavin Adenine Dinucleotide Synthase2 3 | | RP11-307C12.72 | | FAD Pyrophosphorylase2 3 | | FAD Synthase2 | | FMN Adenylyltransferase2 3 | | FAD Synthetase2 | | EC 2.7.7.23 8 | | Fad1, Flavin Adenine Dinucleotide Synthetase, Homolog2 | | FADS2 5 | | Flavin Adenine Dinucleotide Synthetase2 | | PP5911 | | EC 2.7.78 |
Export aliases for FLAD1 gene to outside databasesPrevious GC identifers: GC01P151769 GC01P153222 GC01P126317 |
Summaries for FLAD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for FLAD1: This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adeninedinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: FAD1_HUMAN, Q8NFF5Function: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme
|
Genomic Views for FLAD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FLAD1 gene promoter: CREB AP-1 deltaCREB ATF-2 c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for FLAD1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FLAD1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q22FLAD1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P154955: view genomic region
(about GC identifiers)
Start:
|
154,955,770 bp from pter |
End:
|
154,965,587 bp from pter |
Size:
|
9,818 bases |
Orientation:
|
plus strand |
|
Proteins for FLAD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: FAD1_HUMAN, Q8NFF5 (See
protein sequence)Recommended Name: FAD synthase Size: 587 amino acids; 65266 Da
Cofactor: Magnesium
Secondary accessions: Q8N5J1 Q8N686 Q8WU93 Q8WUJ4 Q96CR8 Q99764 Q9HBN6Alternative splicing: 5 isoforms: Q8NFF5-1 Q8NFF5-2 Q8NFF5-3 Q8NFF5-4 Q8NFF5-5 Explore the universe of human proteins at neXtProt for FLAD1: NX_Q8NFF5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NFF5 4/5 DME Specific Peptides for FLAD1 (Q8NFF5) (see all 5)
FLAD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001171820.1 NP_001171821.1 NP_079483.3 NP_958800.1 ENSEMBL proteins: ENSP00000357418 ENSP00000317296 ENSP00000357417 ENSP00000357416 ENSP00000292180 ENSP00000295530 ENSP00000357413 ENSP00000384323 Reactome Protein details: Q8NFF5 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- |
FLAD1 for ontologies About GeneDecksing
FLAD1 Antibody Products: Assay Products for FLAD1: |
Protein
Domains / Families for FLAD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FLAD1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NFF5ProtoNet protein and cluster: Q8NFF5 UniProtKB/Swiss-Prot: FAD1_HUMAN, Q8NFF5Domain: The molybdenum cofactor biosynthesis protein-like region may not be functionalSimilarity: In the N-terminal section; belongs to the MoaB/Mog familySimilarity: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily |
Function for FLAD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: FAD1_HUMAN, Q8NFF5Function: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzymeCatalytic activity: ATP + FMN = diphosphate + FADBiophysicochemical properties: Kinetic parameters: KM=1.5 uM for FMN (PubMed:16643857); KM=0.36 uM for FMN (isoform 2)(PubMed:17049878); Vmax=6.1 nmol/min/mg enzyme (PubMed:16643857); Vmax=3.9 nmol/min/mg enzyme (isoform 2)(PubMed:17049878);Enzyme Numbers (IUBMB): EC 2.7.7.21 2 EC 2.7.72
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FLAD1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FLAD1 (see all 6) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): FLAD1 (NM_025207) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FLAD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FLAD1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FLAD1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
FLAD1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for FLAD1:
|
Pathways & Interactions for FLAD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Riboflavin metabolism | | | 3 | Vitamin B5 (pantothenate) metabolism | | | 4 | Selenium Pathway | | | 5 | flavin biosynthesis IV (mammalian) | |
Pathway sources See GeneCards unified pathways Show all pathways
2 BioSystems Pathways for FLAD1 
4
Reactome Pathways for FLAD1
2
Kegg Pathways (Kegg details for FLAD1): UniProtKB/Swiss-Prot: FAD1_HUMAN, Q8NFF5Pathway: Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1
FLAD1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FLAD1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
 5/251 Interacting proteins for FLAD1 (Q8NFF52, 3 ENSP000002921804) via UniProtKB, MINT, STRING, and/or I2D (see all 251) About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006747 | FAD biosynthetic process |
IEA | -- | | GO:0006766 | vitamin metabolic process |
TAS | -- | | GO:0006767 | water-soluble vitamin metabolic process |
TAS | -- | | GO:0006771 | riboflavin metabolic process |
TAS | -- | | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process |
IEA | -- |
FLAD1 for ontologies About GeneDecksing
|
Drugs & Compounds for FLAD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
FLAD1 for compounds About GeneDecksing
Browse Tocris compounds for FLAD1
6 HMDB Compounds for FLAD1 About this table 4 Novoseek chemical compound relationships for FLAD1 gene About this table
Search CenterWatch for drugs/clinical trials and news about FLAD1 / FAD1 
|
Transcripts for FLAD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for FLAD1 gene (4 alternative transcripts): NM_001184891.1 NM_001184892.1 NM_025207.4 NM_201398.2 Unigene Cluster for FLAD1: FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) Hs.118666 [show with all ESTs]Unigene Representative Sequence: NM_02520713 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000492620 ENST00000368433(uc001fgd.2) ENST00000315144(uc001fge.2) ENST00000368432(uc001fgg.2) ENST00000368431(uc001fgc.3) ENST00000292180(uc001fgf.2) ENST00000487371 ENST00000295530(uc001fgh.1) ENST00000368428 ENST00000489992 ENST00000477609 ENST00000481758 ENST00000405236
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FLAD1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FLAD1 (see all 6) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): FLAD1 (NM_025207) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FLAD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FLAD1  |
Additional cDNA sequence: AF218022.1 AF481877.1 AF520568.1 AK025979.1 AK308243.1 AY545550.1 BC011378.1 BC014012.2 BC020253.1 BC021096.1 BC032323.1 DQ458779.1 U79241.1 24 DOTS entries: DT.100829891 DT.444810 DT.100029164 DT.95253193 DT.100828220 DT.121413889 DT.100699547 DT.100828208 DT.121413714 DT.100828210 DT.100029162 DT.87011710 DT.100828216 DT.92436438 DT.121413938 DT.92436440 DT.86994148 DT.92436441 DT.121413836 DT.121413907 DT.92436436 DT.121413964 DT.87015794 DT.95253197 24/300 AceView cDNA sequences (see all 300): U79241 BE733323 BG285944 Z45642 BQ918747 BE314012 CR606793 BF528674 AW593854 CA455034 BM696968 BI754823 BU181903 BU175895 Z41315 BQ939808 BE791982 BI521295 BU943923 AK090542 CR617327 AA640012 AA628718 BE502278 GeneLoc Exon Structure
5/17 Alternative Splicing Database (ASD) splice patterns (SP) for FLAD1 (see all 17) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | |
| SP1: | |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | - |   | - |   | |
| SP5: | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 12 | ^ | 13a | · | 13b | |
| SP1: | |   | |   | |   | |
| SP2: | |   | |   | |   | |
| SP3: | |   | |   | |   | |
| SP4: | |   | |   | |   | |
| SP5: | |   | |   | |   |
ECgene alternative splicing isoforms for FLAD1
|
Expression for FLAD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FLAD1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: ACCTCCCACC
About this image See FLAD1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FLAD1
SOURCE GeneReport for Unigene cluster: Hs.118666 SABiosciences Custom PCR Arrays for FLAD1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FLAD1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FLAD1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FLAD1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FLAD1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FLAD1 |
Orthologs for FLAD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FLAD1 gene from 10/34 species (see all 34) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Flad11 , 5 |
RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) less1, 5 |
86.23(n)1 89.98(a)1 |
  |
3 (39.10 cM)5 3199451 NM_177041.31 NP_796015.21 894010045 |
chicken (Gallus gallus) |
Aves |
LOC1008578981 |
FAD synthase-like |
64.17(n) 62.96(a) |
  |
100857898 XM_003642661.1 XP_003642709.1 |
lizard (Anolis carolinensis) |
Reptilia |
FLAD16 |
-- |
62(a) |
1 ↔ 1 |
GL344514.1(24222-30370) |
African clawed frog (Xenopus laevis) |
Amphibia |
CF548370.12 |
-- |
75.79(n) |
  |
CF548370.1 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.272122 |
Transcribed sequence with weak similarity to protein refNP_079483.1 (H.sapiens) hypothetical protein PP591 [Homo sapiens] less |
70.38(n) |
  |
57055166 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG168481 |
CG16848 |
49.84(n) 44.81(a) |
  |
34759 NM_135809.1 NP_609653.1 |
worm (Caenorhabditis elegans) |
Secernentea |
flad-11 |
Protein FLAD-1 |
46.82(n) 40.25(a) |
  |
3565030 NM_001027115.1 NP_001022286.1 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
FAD1(YDL045C)4 FAD11 |
Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin less4 Fad1p1 |
44.94(n)1 36.32(a)1 |
  |
4(373608-372688)4 8515161, 4 NP_010239.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT5G034306 |
phosphoadenosine phosphosulfate (PAPS) reductase f... |
18(a) |
1 ↔ 1 |
5(848864-853142) |
rice (Oryza sativa) |
Liliopsida |
-- |
phosphoadenosine phosphosulfate, putative, express... |
17(a) |
1 ↔ 1 |
1(8700159-8707630) |
ENSEMBL Gene Tree for FLAD1 (if available) TreeFam Gene Tree for FLAD1 (if available)  |
Paralogs for FLAD1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for FLAD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for FLAD1 (154955770 - 154965587 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FLAD1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FLAD1 |
|
Disorders
/ Diseases for FLAD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FLAD1 for disorders About GeneDecksing
OMIM gene information: 610595
OMIM disorders: --
12 diseases for FLAD1: About MalaCardscholinergic urticaria localized osteosarcoma amyotrophic lateral sclerosis phimosis hydranencephaly lateral sclerosis polyhydramnios urticaria nasopharyngitis osteosarcoma malaria carcinoma 4 diseases from the University of Copenhagen DISEASES database for FLAD1:Associative agnosia Phimosis Localized osteosarcoma Cholinergic urticaria Export disorders for FLAD1 gene to outside databases
|
Publications for FLAD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FLAD1 gene, integrated from 9 sources (see all 32): (articles sorted by number of sources associating them with FLAD1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase. (PubMed id 16643857)1, 2, 9 Brizio C.... Barile M. (2006)
- Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 2 Yu W.... Gibbs R.A. (1997)
- Specific electron transport chain abnormalities in amyotrophic lateral sclerosis. (PubMed id 19240958)1, 9 Lin J....Sadiq S.A. (2009)
- Over-expression in Escherichia coli, purification and characterization of isoform 2 of human FAD synthetase. (PubMed id 17049878)2, 9 Galluccio M.... Barile M. (2007)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (2010)
|
External Searches for FLAD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing FLAD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FLAD1 gene
(According to HUGE)
About This Section
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Specialized Databases showing FLAD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for FLAD1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FLAD1 gene: Search GeneIP for patents involving FLAD1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for FLAD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for FLAD1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FLAD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FLAD1 | | OriGene Protein Over-expression Lysate for FLAD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for FLAD1 | | OriGene 3'-UTR Clone for FLAD1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FLAD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FLAD1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for FLAD1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for FLAD1 | | OriGene Custom Protein Services for FLAD1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FLAD1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FLAD1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FLAD1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FLAD1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FLAD1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FLAD1 |
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| | | Search Tocris compounds for FLAD1 |
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 | | FLAD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FLAD1 |
|  |  |  | | | ThermoFisher Antibodies for FLAD1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FLAD1 |
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