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Aliases for HYMAI Gene

Subcategory (RNA class) for HYMAI Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for HYMAI Gene

  • Hydatidiform Mole Associated And Imprinted (Non-Protein Coding) 2 3 5
  • Non-Protein Coding RNA 20 2
  • NCRNA00020 3

External Ids for HYMAI Gene

Previous GeneCards Identifiers for HYMAI Gene

  • GC06U990239
  • GC06M144365
  • GC06M141887

Summaries for HYMAI Gene

Entrez Gene Summary for HYMAI Gene

  • This gene, which encodes a non-protein coding transcript, exhibits differential DNA methylation between the two parental alleles at an adjacent CpG island, and is expressed only from the paternal allele. It is believed to be one of the causative genes for transient neonatal diabetes mellitus (TNDM), which is a rare disease characterized by intrauterine growth retardation, dehydration, and failure to thrive due to a lack of normal insulin secretion. [provided by RefSeq, Oct 2010]

GeneCards Summary for HYMAI Gene

HYMAI (Hydatidiform Mole Associated And Imprinted (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with HYMAI include diabetes mellitus, transient neonatal, 1 and paternal uniparental disomy of chromosome 6.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HYMAI Gene

Genomics for HYMAI Gene

Regulatory Elements for HYMAI Gene

Promoters for HYMAI Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around HYMAI on UCSC Golden Path with GeneCards custom track

Genomic Location for HYMAI Gene

Chromosome:
6
Start:
144,002,886 bp from pter
End:
144,008,730 bp from pter
Size:
5,845 bases
Orientation:
Minus strand

Genomic View for HYMAI Gene

Genes around HYMAI on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HYMAI Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HYMAI Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for HYMAI Gene

Proteins for HYMAI Gene

Post-translational modifications for HYMAI Gene

No Post-translational modifications

No data available for DME Specific Peptides for HYMAI Gene

Domains & Families for HYMAI Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for HYMAI Gene

Function for HYMAI Gene

Human Phenotype Ontology for HYMAI Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for HYMAI Gene

Localization for HYMAI Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for HYMAI Gene

Pathways & Interactions for HYMAI Gene

SuperPathways for HYMAI Gene

No Data Available

Interacting Proteins for HYMAI Gene

Gene Ontology (GO) - Biological Process for HYMAI Gene

None

No data available for Pathways by source and SIGNOR curated interactions for HYMAI Gene

Drugs & Compounds for HYMAI Gene

No Compound Related Data Available

Transcripts for HYMAI Gene

mRNA/cDNA for HYMAI Gene

(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for HYMAI Gene

Hydatidiform mole associated and imprinted (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HYMAI Gene

No ASD Table

Relevant External Links for HYMAI Gene

GeneLoc Exon Structure for
HYMAI
ECgene alternative splicing isoforms for
HYMAI

Expression for HYMAI Gene

mRNA expression in normal human tissues for HYMAI Gene

SOURCE GeneReport for Unigene cluster for HYMAI Gene Hs.657760

genes like me logo Genes that share expression patterns with HYMAI: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for HYMAI Gene

Orthologs for HYMAI Gene

Evolution for HYMAI Gene

ENSEMBL:
Gene Tree for HYMAI (if available)
TreeFam:
Gene Tree for HYMAI (if available)

No data available for Orthologs for HYMAI Gene

Paralogs for HYMAI Gene

No data available for Paralogs for HYMAI Gene

Variants for HYMAI Gene

Structural Variations from Database of Genomic Variants (DGV) for HYMAI Gene

Variant ID Type Subtype PubMed ID
nsv830830 CNV Gain 17160897
nsv5516 CNV Loss 18451855

Relevant External Links for HYMAI Gene

HapMap Linkage Disequilibrium report
HYMAI

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for HYMAI Gene

Disorders for HYMAI Gene

MalaCards: The human disease database

(3) MalaCards diseases for HYMAI Gene - From: Orphanet and GeneCards

Disorder Aliases PubMed IDs
diabetes mellitus, transient neonatal, 1
  • diabetes mellitus, transient neonatal
paternal uniparental disomy of chromosome 6
  • upd(6)pat
diabetes mellitus, 6q24-related transient neonatal
  • diabetes mellitus, transient neonatal, 1
- elite association - COSMIC cancer census association via MalaCards
Search HYMAI in MalaCards View complete list of genes associated with diseases

Relevant External Links for HYMAI

Genetic Association Database (GAD)
HYMAI
Human Genome Epidemiology (HuGE) Navigator
HYMAI
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HYMAI
genes like me logo Genes that share disorders with HYMAI: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HYMAI Gene

Publications for HYMAI Gene

  1. Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach. (PMID: 16873690) Gloyn A.L. … Frayling T.M. (Diabetes 2006) 3 48 67
  2. A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC. (PMID: 10936046) Arima T. … Surani M.A. (Genomics 2000) 2 3
  3. Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop. (PMID: 23295672) Iglesias-Platas I. … Monk D. (Nucleic Acids Res. 2013) 3
  4. Prenatal diagnosis of trisomy 6 rescue resulting in paternal UPD6 with novel placental findings. (PMID: 21739591) Cajaiba M.M. … Surti U. (Am. J. Med. Genet. A 2011) 3
  5. Further refinement of the critical minimal genetic region for the imprinting disorder 6q24 transient neonatal diabetes. (PMID: 20668833) Docherty L.E. … Mackay D.J. (Diabetologia 2010) 3

Products for HYMAI Gene

Sources for HYMAI Gene

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