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Aliases for HLA-DQA1 Gene

Aliases for HLA-DQA1 Gene

  • Major Histocompatibility Complex, Class II, DQ Alpha 1 2 3 5
  • MHC Class II DQA1 3 4
  • DC-1 Alpha Chain 3 4
  • DC-Alpha 3 4
  • HLA-DCA 3 4
  • HLA Class II Histocompatibility Antigen, DQ(W3) Alpha Chain 3
  • MHC Class II HLA-D Alpha Glycoprotein 3
  • MHC Class II Surface Glycoprotein 3
  • Leukocyte Antigen Alpha Chain 3
  • MHC Class II HLA-DQ-Alpha-1 3
  • Leucocyte Antigen DQA1 3
  • MHC Class II Antigen 3
  • MHC HLA-DQ Alpha 3
  • CELIAC1 3
  • HLA-DQA 3
  • DQ-A1 3
  • GSE 3
  • CD 3

External Ids for HLA-DQA1 Gene

Previous HGNC Symbols for HLA-DQA1 Gene

  • HLA-DQA

Previous GeneCards Identifiers for HLA-DQA1 Gene

  • GC06P032649
  • GC06Pd32632
  • GC06P032375
  • GC06P032714
  • GC06P032595
  • GC06P032346

Summaries for HLA-DQA1 Gene

Entrez Gene Summary for HLA-DQA1 Gene

  • HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]

GeneCards Summary for HLA-DQA1 Gene

HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ Alpha 1) is a Protein Coding gene. Diseases associated with HLA-DQA1 include celiac disease and creutzfeldt-jakob disease. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include peptide antigen binding and MHC class II receptor activity. An important paralog of this gene is HLA-DMA.

UniProtKB/Swiss-Prot for HLA-DQA1 Gene

  • Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and efficient peptide loading.

Gene Wiki entry for HLA-DQA1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for HLA-DQA1 Gene

Genomics for HLA-DQA1 Gene

Regulatory Elements for HLA-DQA1 Gene

Genomic Location for HLA-DQA1 Gene

Chromosome:
6
Start:
32,628,179 bp from pter
End:
32,654,774 bp from pter
Size:
26,596 bases
Orientation:
Plus strand

Genomic View for HLA-DQA1 Gene

Genes around HLA-DQA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
HLA-DQA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for HLA-DQA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for HLA-DQA1 Gene

  • Protein details for HLA-DQA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01909-DQA1_HUMAN
    Recommended name:
    HLA class II histocompatibility antigen, DQ alpha 1 chain
    Protein Accession:
    P01909
    Secondary Accessions:
    • O19630
    • O19706
    • P01907
    • P01908
    • P04225
    • P04226
    • P05536
    • P79553
    • Q06751
    • Q29876
    • Q29994
    • Q2Q6Y6
    • Q2Q6Y7
    • Q2Q6Y8
    • Q2WCM3
    • Q30064
    • Q30067
    • Q30068
    • Q30070
    • Q30071
    • Q30072
    • Q30073
    • Q30086
    • Q30101
    • Q5Y7D5
    • Q5Y7F5
    • Q6ICU6
    • Q6PR46
    • Q6QDB1
    • Q860W2
    • Q860W4
    • Q9BD37
    • Q9TPM3
    • Q9UM31

    Protein attributes for HLA-DQA1 Gene

    Size:
    254 amino acids
    Molecular mass:
    27805 Da
    Quaternary structure:
    • Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of antigenic peptides.
    SequenceCaution:
    • Sequence=AAD56720.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for HLA-DQA1 Gene

neXtProt entry for HLA-DQA1 Gene

Proteomics data for HLA-DQA1 Gene at MOPED

Post-translational modifications for HLA-DQA1 Gene

  • Glycosylation at Asn 103 and Asn 143

Other Protein References for HLA-DQA1 Gene

Antibody Products

No data available for DME Specific Peptides for HLA-DQA1 Gene

Domains & Families for HLA-DQA1 Gene

Graphical View of Domain Structure for InterPro Entry

P01909

UniProtKB/Swiss-Prot:

DQA1_HUMAN :
  • Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Belongs to the MHC class II family.
Domain:
  • Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
Family:
  • Belongs to the MHC class II family.
genes like me logo Genes that share domains with HLA-DQA1: view

Function for HLA-DQA1 Gene

Molecular function for HLA-DQA1 Gene

GENATLAS Biochemistry:
HLA-DQ,alpha chain
UniProtKB/Swiss-Prot Function:
Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and efficient peptide loading.
genes like me logo Genes that share phenotypes with HLA-DQA1: view

Human Phenotype Ontology for HLA-DQA1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for HLA-DQA1 Gene

MGI Knock Outs for HLA-DQA1:

Animal Model Products

CRISPR Products

miRNA for HLA-DQA1 Gene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for HLA-DQA1 Gene

Localization for HLA-DQA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for HLA-DQA1 Gene

Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for HLA-DQA1 Gene COMPARTMENTS Subcellular localization image for HLA-DQA1 gene
Compartment Confidence
extracellular 2
mitochondrion 2
plasma membrane 2
cytosol 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for HLA-DQA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010008 endosome membrane IEA --
GO:0012507 ER to Golgi transport vesicle membrane TAS --
GO:0016020 membrane IEA,IDA 19946888
GO:0030666 endocytic vesicle membrane TAS --
GO:0032588 trans-Golgi network membrane TAS --
genes like me logo Genes that share ontologies with HLA-DQA1: view

Pathways & Interactions for HLA-DQA1 Gene

genes like me logo Genes that share pathways with HLA-DQA1: view

Gene Ontology (GO) - Biological Process for HLA-DQA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IEA --
GO:0019221 cytokine-mediated signaling pathway TAS --
GO:0019882 antigen processing and presentation IEA --
genes like me logo Genes that share ontologies with HLA-DQA1: view

No data available for SIGNOR curated interactions for HLA-DQA1 Gene

Drugs & Compounds for HLA-DQA1 Gene

(6) Drugs for HLA-DQA1 Gene - From: PharmGKB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Azathioprine Approved Pharma 153
Interferon beta-1a Approved, Investigational Pharma 194
Interferon beta-1b Approved Pharma 82
Lapatinib Approved March 2007, Investigational Pharma EGFR/HER2 inhibitor,potent,selective and reversible, HER2 and EGFR kinase inhibitor, HER2 Inhibitors, Kinase Inhibitors, Epidermal growth factor receptor (EGFR) inhibitors 294
Mercaptopurine Approved Pharma 0

(7) Additional Compounds for HLA-DQA1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with HLA-DQA1: view

Transcripts for HLA-DQA1 Gene

Unigene Clusters for HLA-DQA1 Gene

Major histocompatibility complex, class II, DQ alpha 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for HLA-DQA1 Gene

No ASD Table

Relevant External Links for HLA-DQA1 Gene

GeneLoc Exon Structure for
HLA-DQA1
ECgene alternative splicing isoforms for
HLA-DQA1

Expression for HLA-DQA1 Gene

mRNA expression in normal human tissues for HLA-DQA1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for HLA-DQA1 Gene

This gene is overexpressed in Spleen (x4.1).

Protein differential expression in normal tissues from HIPED for HLA-DQA1 Gene

This gene is overexpressed in Skin (19.3), Blymphocyte (17.6), Monocytes (7.2), Lymph node (6.9), and Oral epithelium (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for HLA-DQA1 Gene



SOURCE GeneReport for Unigene cluster for HLA-DQA1 Gene Hs.387679

genes like me logo Genes that share expression patterns with HLA-DQA1: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for HLA-DQA1 Gene

Orthologs for HLA-DQA1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for HLA-DQA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PATR-DQA1 35
  • 94.38 (n)
  • 90.98 (a)
-- 36
  • 91 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia BOLA-DQA1 36
  • 79 (a)
ManyToMany
BOLA-DQA2 36
  • 58 (a)
ManyToMany
BOLA-DQA5 36
  • 78 (a)
ManyToMany
LOC100848815 35
  • 84.58 (n)
  • 78.43 (a)
dog
(Canis familiaris)
Mammalia DLA-DQA 36
  • 46 (a)
OneToMany
mouse
(Mus musculus)
Mammalia H2-Aa 16
H2-Aa 36
  • 71 (a)
OneToMany
H2-Aa 35
  • 80.91 (n)
  • 72.2 (a)
rat
(Rattus norvegicus)
Mammalia RT1-Ba 35
  • 80.45 (n)
  • 74.41 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii si:busm1-266f07.2 36
  • 33 (a)
ManyToMany
Species with no ortholog for HLA-DQA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for HLA-DQA1 Gene

ENSEMBL:
Gene Tree for HLA-DQA1 (if available)
TreeFam:
Gene Tree for HLA-DQA1 (if available)

Paralogs for HLA-DQA1 Gene

(31) SIMAP similar genes for HLA-DQA1 Gene using alignment to 194 proteins:

genes like me logo Genes that share paralogs with HLA-DQA1: view

Variants for HLA-DQA1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for HLA-DQA1 Gene

P01909-DQA1_HUMAN
DQ2 (heterodimer of DQA1*05:01/DQB1*02:01) is associated with more than 90% of celiac disease patients. A minority displays DQ8 (heterodimer of DQA1*03/DQB1*03:02). DQ0602 (heterodimer of DQA1*01:02/DQB1*06:02) confers dominant protection against type 1 diabetes (T1D) and strong susceptibility to narcolepsy.

Sequence variations from dbSNP and Humsavar for HLA-DQA1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10093 - 32,641,396(+) ATGAG(C/G)AGTTC reference, missense
rs1047989 - 32,637,480(+) CTCTG(A/C)TGCTG reference, missense
rs1047992 - 32,637,489(+) TGGGG(A/G/T)CCCTC reference, missense
rs1071630 - 32,641,349(+) CCAGT(C/T)TTACG reference, missense
rs12722051 - 32,641,370(+) CCAGT(A/T)CACCC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for HLA-DQA1 Gene

Variant ID Type Subtype PubMed ID
dgv1931e1 CNV Complex 17122850
nsv428142 CNV Gain+Loss 18775914
esv21985 CNV Gain+Loss 19812545
esv33476 CNV Gain+Loss 17666407
nsv7883 CNV Gain+Loss 18304495
nsv511120 CNV Complex 20534489
dgv1013n67 CNV Loss 20364138
esv2459937 CNV Loss 19546169
esv2731847 CNV Deletion 23290073
dgv1935e1 CNV Complex 17122850
nsv462881 CNV Loss 19166990
esv2668413 CNV Deletion 23128226
nsv885508 CNV Loss 21882294
dgv750n27 CNV Loss 19166990
nsv830632 CNV Loss 17160897
dgv6772n71 CNV Loss 21882294
esv2676495 CNV Deletion 23128226
esv2421999 OTHER Complex 20811451
dgv1031n67 CNV Loss 20364138
dgv6773n71 CNV Loss 21882294
dgv6774n71 CNV Loss 21882294
nsv885517 CNV Loss 21882294
dgv6775n71 CNV Gain 21882294
dgv6776n71 CNV Loss 21882294
dgv6777n71 CNV Loss 21882294
esv2673715 CNV Deletion 23128226
esv1003385 CNV Gain 20482838
dgv6778n71 CNV Loss 21882294
dgv6779n71 CNV Loss 21882294
dgv6780n71 CNV Gain+Loss 21882294
dgv6781n71 CNV Gain+Loss 21882294
dgv6782n71 CNV Loss 21882294
dgv1046e201 CNV Deletion 23290073
dgv6783n71 CNV Loss 21882294
nsv525222 CNV Loss 19592680
nsv885558 CNV Gain 21882294
esv2676540 CNV Deletion 23128226
dgv1032n67 CNV Loss 20364138
dgv1033n67 CNV Loss 20364138
dgv1034n67 CNV Loss 20364138
esv32765 CNV Gain 17666407
dgv6784n71 CNV Gain 21882294
nsv885564 CNV Gain 21882294
dgv6785n71 CNV Loss 21882294
esv998922 CNV Gain 20482838
dgv1035n67 CNV Loss 20364138
dgv6786n71 CNV Gain 21882294
dgv6787n71 CNV Gain+Loss 21882294
dgv6788n71 CNV Gain 21882294
dgv6789n71 CNV Loss 21882294
nsv514351 CNV Loss 21397061
dgv6790n71 CNV Gain 21882294
dgv6791n71 CNV Gain 21882294
dgv6792n71 CNV Loss 21882294
dgv6793n71 CNV Gain 21882294
dgv6794n71 CNV Gain+Loss 21882294
esv2421710 CNV Deletion 20811451
nsv823622 CNV Loss 20364138
dgv6795n71 CNV Loss 21882294
dgv1110e199 CNV Deletion 23128226
dgv6796n71 CNV Loss 21882294
nsv823623 CNV Loss 20364138
dgv1036n67 CNV Loss 20364138
nsv820032 CNV Gain 19587683
esv29995 CNV Gain 17803354

Variation tolerance for HLA-DQA1 Gene

Residual Variation Intolerance Score: 99.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 27.60; 99.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for HLA-DQA1 Gene

HapMap Linkage Disequilibrium report
HLA-DQA1
Human Gene Mutation Database (HGMD)
HLA-DQA1

Disorders for HLA-DQA1 Gene

MalaCards: The human disease database

(40) MalaCards diseases for HLA-DQA1 Gene - From: OMIM, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
celiac disease
  • celiac sprue
creutzfeldt-jakob disease
  • creutzfeldt-jakob disease, variant
blau syndrome
  • sarcoidosis, early-onset
sarcoidosis, early-onset
  • early onset sarcoidosis
multiple sclerosis, disease progression, modifier of
  • multiple sclerosis 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for HLA-DQA1

Genetic Association Database (GAD)
HLA-DQA1
Human Genome Epidemiology (HuGE) Navigator
HLA-DQA1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
HLA-DQA1
genes like me logo Genes that share disorders with HLA-DQA1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for HLA-DQA1 Gene

Publications for HLA-DQA1 Gene

  1. Association between HLA-DQA1, -DQB1 gene polymorphisms and susceptibility to asthma in northern Chinese subjects. (PMID: 12890388) Gao J. … Liu Y. (Chin. Med. J. 2003) 3 23 48 67
  2. Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes. (PMID: 20061363) Kohno T. … Yokota J. (Carcinogenesis 2010) 3 23
  3. Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes. (PMID: 19143818) Bronson P.G. … Barcellos L.F. (Diabetes Obes Metab 2009) 3 23
  4. HLA class II polymorphism in children with coeliac disease in Tunisia: is there any influence on clinical manifestation? (PMID: 19474744) Laadhar L. … Ben Hariz M. (Eur J Gastroenterol Hepatol 2009) 3 23
  5. HLA-DQA1 gene expression profiling in oligoarticular JIA. (PMID: 19811310) Haas J.P. … Wassmuth R. (Autoimmunity 2009) 3 23

Products for HLA-DQA1 Gene

Sources for HLA-DQA1 Gene

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