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Aliases for TRA Gene

Aliases for TRA Gene

  • T-Cell Receptor Alpha Locus 2 3
  • T Cell Receptor Alpha Locus 2 3
  • T-Cell Antigen Receptor, Alpha Polypeptide 3
  • T-Cell Receptor, Alpha (V,D,J,C) 3
  • TRAC 3
  • IMD7 3
  • TCRD 3
  • TCRA 3
  • TRA@ 3

External Ids for TRA Gene

Previous HGNC Symbols for TRA Gene

  • TCRA
  • TRA@

Previous GeneCards Identifiers for TRA Gene

  • GC14P022093

Summaries for TRA Gene

GeneCards Summary for TRA Gene

TRA (T-Cell Receptor Alpha Locus) is a Protein Coding gene. Diseases associated with TRA include Immunodeficiency 7, Tcr-Alpha/Beta Deficient and Precursor T-Cell Acute Lymphoblastic Leukemia. Among its related pathways are Immune response Antigen presentation by MHC class II and Immune response NFAT in immune response.

Gene Wiki entry for TRA Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRA Gene

Genomics for TRA Gene

Regulatory Elements for TRA Gene

Enhancers for TRA Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TRA on UCSC Golden Path with GeneCards custom track

Genomic Location for TRA Gene

Chromosome:
14
Start:
21,621,904 bp from pter
End:
22,552,132 bp from pter
Size:
930,229 bases
Orientation:
Plus strand

Genomic View for TRA Gene

Genes around TRA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRA Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRA Gene

Proteins for TRA Gene

  • Protein details for TRA Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0C4ZLG8
    Recommended name:
    TRA protein
    Protein Accession:
    A0A0C4ZLG8

    Protein attributes for TRA Gene

    Size:
    187 amino acids
    Molecular mass:
    20713 Da
    Quaternary structure:
    No Data Available
  • Protein details for TRA Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0C4ZNA2
    Recommended name:
    TRA protein
    Protein Accession:
    A0A0C4ZNA2

    Protein attributes for TRA Gene

    Size:
    132 amino acids
    Molecular mass:
    14614 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRA Gene

Proteomics data for TRA Gene at MOPED

Post-translational modifications for TRA Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRA Gene

Domains & Families for TRA Gene

Gene Families for TRA Gene

Protein Domains for TRA Gene

Suggested Antigen Peptide Sequences for TRA Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRA: view

No data available for UniProtKB/Swiss-Prot for TRA Gene

Function for TRA Gene

Phenotypes for TRA Gene

GenomeRNAi human phenotypes for TRA:
genes like me logo Genes that share phenotypes with TRA: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRA Gene

Localization for TRA Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRA Gene

Drugs & Compounds for TRA Gene

(1) Drugs for TRA Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(2) Additional Compounds for TRA Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TRA: view

Transcripts for TRA Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRA Gene

No ASD Table

Relevant External Links for TRA Gene

GeneLoc Exon Structure for
TRA
ECgene alternative splicing isoforms for
TRA

No data available for mRNA/cDNA for TRA Gene

Expression for TRA Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRA Gene

Orthologs for TRA Gene

No data available for Orthologs and Evolution for TRA Gene

Paralogs for TRA Gene

No data available for Paralogs for TRA Gene

Variants for TRA Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for TRA Gene

Disorders for TRA Gene

MalaCards: The human disease database

(4) MalaCards diseases for TRA Gene - From: OMIM, Orphanet, and GeneCards

Disorder Aliases PubMed IDs
immunodeficiency 7, tcr-alpha/beta deficient
  • immunodeficiency 7
precursor t-cell acute lymphoblastic leukemia
  • precursor t-cell acute lymphoblastic leukemia/lymphoma
allergic encephalomyelitis
  • experimental autoimmune encephalomyelitis
hypersomnia
- elite association - COSMIC cancer census association via MalaCards
Search TRA in MalaCards View complete list of genes associated with diseases

Relevant External Links for TRA

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRA
genes like me logo Genes that share disorders with TRA: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRA Gene

Publications for TRA Gene

  1. The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia. (PMID: 3875483) Rabbitts T.H. … Goodfellow P.N. (EMBO J. 1985) 2 3 67
  2. Pre T-cell receptor alpha (pTalpha) expression patterns and functional analysis in human T-cell lymphoblastic leukemia. (PMID: 20208138) Ivanyi P. … Franzke A. (Cell. Oncol. 2010) 3 23
  3. Gene-specific signal joint modifications during V(D)J recombination of TCRAD locus genes in murine and human thymocytes. (PMID: 17015149) Touvrey C. … CandAcias S.M. (Immunobiology 2006) 3 23
  4. Locus of the alpha-chain of the T-cell receptor is split by chromosome translocation in T-cell leukemias. (PMID: 3875152) Erikson J. … Croce C.M. (Science 1985) 2 3
  5. The macrophage-TCRI+I^ is a cholesterol-responsive combinatorial immune receptor and implicated in atherosclerosis. (PMID: 25446098) Fuchs T. … Kaminski W.E. (Biochem. Biophys. Res. Commun. 2015) 3

Products for TRA Gene

Sources for TRA Gene

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