Aliases for PMPCB Gene
External Ids for PMPCB Gene
Previous GeneCards Identifiers for PMPCB Gene
This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008]
GeneCards Summary for PMPCB Gene
PMPCB (Peptidase (Mitochondrial Processing) Beta) is a Protein Coding gene. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Mitochondrial Protein Import. GO annotations related to this gene include metalloendopeptidase activity. An important paralog of this gene is UQCRC1.
UniProtKB/Swiss-Prot for PMPCB Gene
Cleaves presequences (transit peptides) from mitochondrial protein precursors.