Aliases for CYP7B1 Gene
External Ids for CYP7B1 Gene
Previous HGNC Symbols for CYP7B1 Gene
Previous GeneCards Identifiers for CYP7B1 Gene
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for CYP7B1 Gene
CYP7B1 (Cytochrome P450, Family 7, Subfamily B, Polypeptide 1) is a Protein Coding gene. Diseases associated with CYP7B1 include bile acid synthesis defect, congenital, 3 and spastic paraplegia 5a, autosomal recessive. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include electron carrier activity and heme binding. An important paralog of this gene is CYP8B1.