Aliases for LHX2 Gene
External Ids for LHX2 Gene
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHX2 Gene
LHX2 (LIM Homeobox 2) is a Protein Coding gene. Diseases associated with LHX2 include schizencephaly. Among its related pathways are Neural Crest Differentiation. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and RNA polymerase II transcription factor binding transcription factor activity. An important paralog of this gene is LHX4.
UniProtKB/Swiss-Prot for LHX2 Gene
Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).