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Aliases for MAPK1IP1L Gene

Aliases for MAPK1IP1L Gene

  • Mitogen-Activated Protein Kinase 1 Interacting Protein 1-Like 2 3 5
  • Mitogen Activated Protein Kinase 1 Interacting Protein 1-Like 2 3
  • Mitogen-Activated Protein Kinase 1-Interacting Protein 1-Like 3 4
  • C14orf32 3 4
  • MAPK-Interacting And Spindle-Stabilizing Protein 3
  • Chromosome 14 Open Reading Frame 32 2
  • C14_5346 3
  • MISS 3

External Ids for MAPK1IP1L Gene

Previous HGNC Symbols for MAPK1IP1L Gene

  • C14orf32

Previous GeneCards Identifiers for MAPK1IP1L Gene

  • GC14P054589
  • GC14P055518
  • GC14P035680

Summaries for MAPK1IP1L Gene

GeneCards Summary for MAPK1IP1L Gene

MAPK1IP1L (Mitogen-Activated Protein Kinase 1 Interacting Protein 1-Like) is a Protein Coding gene.

Gene Wiki entry for MAPK1IP1L Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAPK1IP1L Gene

Genomics for MAPK1IP1L Gene

Regulatory Elements for MAPK1IP1L Gene

Enhancers for MAPK1IP1L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MAPK1IP1L on UCSC Golden Path with GeneCards custom track

Promoters for MAPK1IP1L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MAPK1IP1L on UCSC Golden Path with GeneCards custom track

Genomic Location for MAPK1IP1L Gene

Chromosome:
14
Start:
55,051,631 bp from pter
End:
55,070,194 bp from pter
Size:
18,564 bases
Orientation:
Plus strand

Genomic View for MAPK1IP1L Gene

Genes around MAPK1IP1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAPK1IP1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAPK1IP1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAPK1IP1L Gene

Proteins for MAPK1IP1L Gene

  • Protein details for MAPK1IP1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NDC0-MISSL_HUMAN
    Recommended name:
    MAPK-interacting and spindle-stabilizing protein-like
    Protein Accession:
    Q8NDC0
    Secondary Accessions:
    • B2RDD8
    • Q96BG5

    Protein attributes for MAPK1IP1L Gene

    Size:
    245 amino acids
    Molecular mass:
    24269 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAPK1IP1L Gene

Proteomics data for MAPK1IP1L Gene at MOPED

Post-translational modifications for MAPK1IP1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAPK1IP1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAPK1IP1L Gene

Domains & Families for MAPK1IP1L Gene

Protein Domains for MAPK1IP1L Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MAPK1IP1L Gene

Graphical View of Domain Structure for InterPro Entry

Q8NDC0

UniProtKB/Swiss-Prot:

MISSL_HUMAN :
  • Belongs to the MISS family.
Family:
  • Belongs to the MISS family.
genes like me logo Genes that share domains with MAPK1IP1L: view

No data available for Gene Families for MAPK1IP1L Gene

Function for MAPK1IP1L Gene

genes like me logo Genes that share phenotypes with MAPK1IP1L: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MAPK1IP1L Gene

Localization for MAPK1IP1L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MAPK1IP1L Gene COMPARTMENTS Subcellular localization image for MAPK1IP1L gene
Compartment Confidence
cytosol 3
nucleus 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAPK1IP1L Gene

Pathways & Interactions for MAPK1IP1L Gene

SuperPathways for MAPK1IP1L Gene

No Data Available

Gene Ontology (GO) - Biological Process for MAPK1IP1L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MAPK1IP1L Gene

Drugs & Compounds for MAPK1IP1L Gene

No Compound Related Data Available

Transcripts for MAPK1IP1L Gene

Unigene Clusters for MAPK1IP1L Gene

Mitogen-activated protein kinase 1 interacting protein 1-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MAPK1IP1L Gene

No ASD Table

Relevant External Links for MAPK1IP1L Gene

GeneLoc Exon Structure for
MAPK1IP1L
ECgene alternative splicing isoforms for
MAPK1IP1L

Expression for MAPK1IP1L Gene

mRNA expression in normal human tissues for MAPK1IP1L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MAPK1IP1L Gene

This gene is overexpressed in NK cells (10.8), Bone marrow stromal cell (9.7), and CD4 Tcells (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for MAPK1IP1L Gene



SOURCE GeneReport for Unigene cluster for MAPK1IP1L Gene Hs.594338

genes like me logo Genes that share expression patterns with MAPK1IP1L: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MAPK1IP1L Gene

Orthologs for MAPK1IP1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for MAPK1IP1L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MAPK1IP1L 35
  • 93.65 (n)
  • 98.41 (a)
MAPK1IP1L 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MAPK1IP1L 35
  • 93.17 (n)
  • 94.67 (a)
MAPK1IP1L 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mapk1ip1l 35
  • 85.06 (n)
  • 78.84 (a)
Mapk1ip1l 16
Mapk1ip1 36
  • 41 (a)
OneToMany
Mapk1ip1l 36
  • 81 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia MAPK1IP1L 35
  • 99.86 (n)
  • 100 (a)
MAPK1IP1L 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mapk1ip1l 35
  • 85.01 (n)
  • 79.41 (a)
oppossum
(Monodelphis domestica)
Mammalia MAPK1IP1L 36
  • 87 (a)
OneToOne
chicken
(Gallus gallus)
Aves MAPK1IP1L 35
  • 74.46 (n)
  • 70.97 (a)
lizard
(Anolis carolinensis)
Reptilia MAPK1IP1L 36
  • 68 (a)
OneToOne
Species with no ortholog for MAPK1IP1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAPK1IP1L Gene

ENSEMBL:
Gene Tree for MAPK1IP1L (if available)
TreeFam:
Gene Tree for MAPK1IP1L (if available)

Paralogs for MAPK1IP1L Gene

Pseudogenes.org Pseudogenes for MAPK1IP1L Gene

genes like me logo Genes that share paralogs with MAPK1IP1L: view

No data available for Paralogs for MAPK1IP1L Gene

Variants for MAPK1IP1L Gene

Sequence variations from dbSNP and Humsavar for MAPK1IP1L Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs7493592 -- 55,059,290(+) ATTGT(A/C)AAGCT intron-variant, upstream-variant-2KB
rs728889 -- 55,059,092(-) CATCT(C/G)GTTCA intron-variant
rs3078612 -- 55,059,243(+) AAAAA(-/AAA)GACAG intron-variant, upstream-variant-2KB
rs3742564 -- 55,063,402(+) TTGGA(C/T)GGAAG intron-variant
rs3742565 -- 55,063,578(+) AGCAG(A/T)GTCCT intron-variant

Variation tolerance for MAPK1IP1L Gene

Residual Variation Intolerance Score: 26.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.48; 10.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAPK1IP1L Gene

HapMap Linkage Disequilibrium report
MAPK1IP1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MAPK1IP1L Gene

Disorders for MAPK1IP1L Gene

Relevant External Links for MAPK1IP1L

Genetic Association Database (GAD)
MAPK1IP1L
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MAPK1IP1L

No disorders were found for MAPK1IP1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAPK1IP1L Gene

Publications for MAPK1IP1L Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 67
  2. Meiotic spindle stability depends on MAPK-interacting and spindle-stabilizing protein (MISS), a new MAPK substrate. (PMID: 12011110) Lefebvre C. … Verlhac M.H. (J. Cell Biol. 2002) 2 3
  3. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3

Products for MAPK1IP1L Gene

Sources for MAPK1IP1L Gene

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