Aliases for ZBED1 Gene
External Ids for ZBED1 Gene
Previous HGNC Symbols for ZBED1 Gene
Previous GeneCards Identifiers for ZBED1 Gene
This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]
GeneCards Summary for ZBED1 Gene
ZBED1 (Zinc Finger, BED-Type Containing 1) is a Protein Coding gene. GO annotations related to this gene include protein dimerization activity and transposase activity. An important paralog of this gene is ZBED4.
UniProtKB/Swiss-Prot for ZBED1 Gene
Binds to 5-TGTCG[CT]GA[CT]A-3 DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.