Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MTA1 Gene

Aliases for MTA1 Gene

  • Metastasis Associated 1 2 3 5

External Ids for MTA1 Gene

Previous GeneCards Identifiers for MTA1 Gene

  • GC14U990075
  • GC14P099877
  • GC14P103858
  • GC14P104957
  • GC14P105886
  • GC14P086101

Summaries for MTA1 Gene

Entrez Gene Summary for MTA1 Gene

  • This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

GeneCards Summary for MTA1 Gene

MTA1 (Metastasis Associated 1) is a Protein Coding gene. Diseases associated with MTA1 include Tonsil Cancer and Esophageal Cancer. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Validated targets of C-MYC transcriptional activation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is MTA2.

UniProtKB/Swiss-Prot for MTA1 Gene

  • Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. As a part of the histone-deacetylase multiprotein complex (NuRD), regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, PAX5 and SUMO2, independent of the NuRD complex. Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3. Plays a role in the inflammatory responses, both as a target and as a component of the NF-kappa-B signaling and regulates a subset of proinflammatory cytokines such as IL1B, MIP2, and TNF. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and MDM2 thereby regulating the p53-dependent DNA repair. Plays an important role in tumorigenesis, tumor invasion, and metastasis. Involved in the epigenetic regulation of ESR1 expression in breast cancer in a TFAP2C, IFI16 and HDAC4/5/6-dependent manner. Plays a role in the regulation of the circadian clock and is essential for the generation and maintenance of circadian rhythms under constant light and for normal entrainment of behavior to light-dark (LD) cycles. Positively regulates the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of its own transcription and the transcription of CRY1. Regulates deacetylation of ARNTL/BMAL1 by regulating SIRT1 expression, resulting in derepressing CRY1-mediated transcription repression. Isoform Short binds to ESR1 and sequesters it in the cytoplasm and enhances its non-genomic responses.

Gene Wiki entry for MTA1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTA1 Gene

Genomics for MTA1 Gene

Regulatory Elements for MTA1 Gene

Enhancers for MTA1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G105479 1.4 ENCODE dbSUPER 4.9 +66.2 66184 13.2 CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC TMEM121 MTA1 ENSG00000257270 C14orf79 CRIP1 CRIP2
GH14G105351 1.4 Ensembl ENCODE dbSUPER 4.6 -67.4 -67390 1.1 ELF3 HDGF ATF1 ARID4B RAD21 RFX5 GLIS2 ZNF143 RELB IKZF2 BRF1 PACS2 MTA1 ENSG00000279495
GH14G105332 1.3 ENCODE dbSUPER 4.5 -85.1 -85072 5.1 ATF1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF48 ZBTB7B SLC30A9 ZNF766 LINC02298 TMEM121 ENSG00000258811 MTA1 CRIP2 BRF1 ENSG00000279495
GH14G105312 1.2 ENCODE dbSUPER 4.4 -104.4 -104383 5.4 PKNOX1 ARID4B SIN3A ZNF48 ZNF766 GLIS2 ELK1 SP3 GLIS1 KDM1A ENSG00000225200 ENSG00000257270 TEX22 NUDT14 JAG2 MTA1 BRF1 GC14M105304
GH14G105323 1 FANTOM5 ENCODE dbSUPER 4.5 -95.3 -95282 1.3 POLR2A ZIC2 MTA1 BRF1 ENSG00000279495
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MTA1 on UCSC Golden Path with GeneCards custom track

Promoters for MTA1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000073819 480 1401 HDGF ZFP64 ZEB1 GLIS2 SCRT2 FOS PCBP1 ZNF263 KLF11 MXD4

Genomic Location for MTA1 Gene

Chromosome:
14
Start:
105,419,820 bp from pter
End:
105,470,729 bp from pter
Size:
50,910 bases
Orientation:
Plus strand

Genomic View for MTA1 Gene

Genes around MTA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MTA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MTA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTA1 Gene

Proteins for MTA1 Gene

  • Protein details for MTA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13330-MTA1_HUMAN
    Recommended name:
    Metastasis-associated protein MTA1
    Protein Accession:
    Q13330
    Secondary Accessions:
    • A5PLK4
    • Q86SW2
    • Q8NFI8
    • Q96GI8

    Protein attributes for MTA1 Gene

    Size:
    715 amino acids
    Molecular mass:
    80786 Da
    Quaternary structure:
    • Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD). Interacts with HDAC1 and ITGB3BP/CENPR. Binds to CSNK1G2 in the cytoplasm. Interacts with NACC2. Interacts with ARNTL/BMAL1 and CLOCK. Interacts with EP300, TFAP2C, IFI16, TPR, HDAC2, UBE2I/UBC9, PIAS1, PIAS3, PIAS4, p53/TP53, MDM2, RFWD2, SUMO1, SUMO2, SENP1 and SENP2. Interacts with SIX3; facilitates the binding of SIX3 to the core DNA motif of SIX3 promoter (By similarity).

    Three dimensional structures from OCA and Proteopedia for MTA1 Gene

    Alternative splice isoforms for MTA1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MTA1 Gene

Post-translational modifications for MTA1 Gene

  • Acetylation is essential for its transcriptional coactivator activity.
  • Phosphorylation by CSNK1G2/CK1 triggered by estrogen enhances corepression of estrogen receptor (ER).
  • Sumoylation positively regulates its transcriptional corepressor activity but does not affect the protein stability. Sumoylated preferentially by SUMO2 or SUMO3 than SUMO1. Sumoylation is enhanced by PIAS1/3/4 and preferentially sumoylated by SUMO2 in the presence of PIAS1/3/4. Desumoylated by SENP1.
  • Ubiquitinated by RFWD2, which leads to proteasomal degradation.
  • Ubiquitination at posLast=182182, posLast=208208, Lys361, posLast=527527, and posLast=6161
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for MTA1 (MTA1)

No data available for DME Specific Peptides for MTA1 Gene

Domains & Families for MTA1 Gene

Suggested Antigen Peptide Sequences for MTA1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13330

UniProtKB/Swiss-Prot:

MTA1_HUMAN :
  • Isoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
Domain:
  • Isoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
genes like me logo Genes that share domains with MTA1: view

Function for MTA1 Gene

Molecular function for MTA1 Gene

UniProtKB/Swiss-Prot Function:
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. As a part of the histone-deacetylase multiprotein complex (NuRD), regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, PAX5 and SUMO2, independent of the NuRD complex. Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3. Plays a role in the inflammatory responses, both as a target and as a component of the NF-kappa-B signaling and regulates a subset of proinflammatory cytokines such as IL1B, MIP2, and TNF. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and MDM2 thereby regulating the p53-dependent DNA repair. Plays an important role in tumorigenesis, tumor invasion, and metastasis. Involved in the epigenetic regulation of ESR1 expression in breast cancer in a TFAP2C, IFI16 and HDAC4/5/6-dependent manner. Plays a role in the regulation of the circadian clock and is essential for the generation and maintenance of circadian rhythms under constant light and for normal entrainment of behavior to light-dark (LD) cycles. Positively regulates the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of its own transcription and the transcription of CRY1. Regulates deacetylation of ARNTL/BMAL1 by regulating SIRT1 expression, resulting in derepressing CRY1-mediated transcription repression. Isoform Short binds to ESR1 and sequesters it in the cytoplasm and enhances its non-genomic responses.

Gene Ontology (GO) - Molecular Function for MTA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001046 core promoter sequence-specific DNA binding ISS --
GO:0001047 core promoter binding IDA 21965678
GO:0001103 RNA polymerase II repressing transcription factor binding IPI 22926524
GO:0003677 DNA binding IEA --
GO:0003682 chromatin binding IEA --
genes like me logo Genes that share ontologies with MTA1: view
genes like me logo Genes that share phenotypes with MTA1: view

Animal Models for MTA1 Gene

MGI Knock Outs for MTA1:

Animal Model Products

  • Taconic Biosciences Mouse Models for MTA1

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MTA1 Gene

Localization for MTA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MTA1 Gene

Isoform Short: Cytoplasm.
Isoform Long: Nucleus. Nucleus envelope. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules. Localization at the nuclear envelope is TPR-dependent.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MTA1 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 5

Gene Ontology (GO) - Cellular Components for MTA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 21965678
GO:0005635 nuclear envelope IDA,IEA 24970816
GO:0005654 nucleoplasm TAS,IDA --
GO:0005737 cytoplasm IEA,IDA 24970816
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with MTA1: view

Pathways & Interactions for MTA1 Gene

genes like me logo Genes that share pathways with MTA1: view

Gene Ontology (GO) - Biological Process for MTA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006302 double-strand break repair IMP 19805145
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0007165 signal transduction TAS 8083195
GO:0010212 response to ionizing radiation IDA 19805145
genes like me logo Genes that share ontologies with MTA1: view

No data available for SIGNOR curated interactions for MTA1 Gene

Drugs & Compounds for MTA1 Gene

(5) Drugs for MTA1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with MTA1: view

Transcripts for MTA1 Gene

Unigene Clusters for MTA1 Gene

Metastasis associated 1:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MTA1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^
SP1: - - - - - -
SP2: - - - - - - -
SP3: - - - -
SP4: - - -
SP5: - - - - - -
SP6: - -
SP7: -
SP8: -
SP9: -
SP10:

ExUns: 22a · 22b ^ 23
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for MTA1 Gene

GeneLoc Exon Structure for
MTA1
ECgene alternative splicing isoforms for
MTA1

Expression for MTA1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MTA1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MTA1 Gene

This gene is overexpressed in Fetal Brain (10.5), Peripheral blood mononuclear cells (9.2), CD8 Tcells (6.5), and Lymph node (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MTA1 Gene



Protein tissue co-expression partners for MTA1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MTA1 Gene:

MTA1

SOURCE GeneReport for Unigene cluster for MTA1 Gene:

Hs.525629

mRNA Expression by UniProt/SwissProt for MTA1 Gene:

Q13330-MTA1_HUMAN
Tissue specificity: Widely expressed. High expression in brain, liver, kidney, and cardiac muscle, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual. Up-regulated in a wide variety of cancers including breast, liver, ovarian, and colorectal cancer and its expression levels are closely correlated with tumor aggressiveness and metastasis.

Evidence on tissue expression from TISSUES for MTA1 Gene

  • Nervous system(4.8)
  • Liver(4.3)
  • Lung(3.1)
  • Lymph node(2.5)
  • Intestine(2.2)
genes like me logo Genes that share expression patterns with MTA1: view

Primer Products

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MTA1 Gene

Orthologs for MTA1 Gene

This gene was present in the common ancestor of animals.

Orthologs for MTA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MTA1 34
  • 99.01 (n)
cow
(Bos Taurus)
Mammalia MTA1 35
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MTA1 35
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MTA1 35
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MTA1 34 35
  • 91.93 (n)
mouse
(Mus musculus)
Mammalia Mta1 34 16 35
  • 89.64 (n)
rat
(Rattus norvegicus)
Mammalia Mta1 34
  • 89.43 (n)
chicken
(Gallus gallus)
Aves MTA1 34 35
  • 78.06 (n)
lizard
(Anolis carolinensis)
Reptilia MTA1 35
  • 87 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mta1 34
  • 75.04 (n)
zebrafish
(Danio rerio)
Actinopterygii MTA1 35
  • 81 (a)
OneToOne
LOC794477 34
  • 75.51 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004341 34
  • 57.8 (n)
fruit fly
(Drosophila melanogaster)
Insecta MTA1-like 34
  • 56.07 (n)
worm
(Caenorhabditis elegans)
Secernentea egr-1 36
  • 40 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1613 34
Species where no ortholog for MTA1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MTA1 Gene

ENSEMBL:
Gene Tree for MTA1 (if available)
TreeFam:
Gene Tree for MTA1 (if available)

Paralogs for MTA1 Gene

Paralogs for MTA1 Gene

genes like me logo Genes that share paralogs with MTA1: view

Variants for MTA1 Gene

Sequence variations from dbSNP and Humsavar for MTA1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000218127 -- 105,456,231(+) GGTGA(A/G)AACAC intron-variant
rs1000239590 -- 105,423,055(+) AGCAT(C/G)CAAAA intron-variant
rs1000374998 -- 105,466,282(+) CAGCC(C/G)AGTCA intron-variant
rs1000378320 -- 105,433,555(+) CCAAG(A/C)CTGCT intron-variant
rs1000435226 -- 105,462,249(+) CTGAA(C/T)CCTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MTA1 Gene

Variant ID Type Subtype PubMed ID
dgv1143n106 CNV deletion 24896259
dgv3987n54 CNV loss 21841781
dgv3988n54 CNV gain 21841781
dgv3989n54 CNV gain 21841781
esv1158347 CNV deletion 17803354
esv1257424 CNV insertion 17803354
esv1287990 CNV insertion 17803354
esv2749293 CNV deletion 23290073
esv2749294 CNV deletion 23290073
esv2749295 CNV deletion 23290073
esv2749297 CNV deletion 23290073
esv2760014 CNV loss 17122850
esv3310519 CNV novel sequence insertion 20981092
esv3360291 CNV insertion 20981092
esv3413895 CNV insertion 20981092
esv3635644 CNV loss 21293372
esv996317 CNV insertion 20482838
esv998455 CNV insertion 20482838
esv999483 CNV insertion 20482838
nsv1054190 CNV gain 25217958
nsv1070248 CNV deletion 25765185
nsv1078210 CNV insertion 25765185
nsv1125600 CNV tandem duplication 24896259
nsv1132866 CNV insertion 24896259
nsv1160204 CNV duplication 26073780
nsv470679 CNV loss 18288195
nsv475394 CNV novel sequence insertion 20440878
nsv478567 CNV novel sequence insertion 20440878
nsv517055 CNV gain+loss 19592680
nsv566189 CNV gain 21841781
nsv566204 CNV gain 21841781
nsv566205 CNV loss 21841781
nsv566206 CNV loss 21841781
nsv566207 CNV loss 21841781
nsv566209 CNV gain+loss 21841781
nsv566210 CNV gain 21841781
nsv817647 CNV gain 17921354
nsv827088 CNV gain 20364138
nsv832890 CNV loss 17160897
nsv84553 CNV insertion 16902084
nsv85362 CNV insertion 16902084
nsv952282 CNV deletion 24416366

Variation tolerance for MTA1 Gene

Residual Variation Intolerance Score: 7.21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.13; 87.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MTA1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MTA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MTA1 Gene

Disorders for MTA1 Gene

MalaCards: The human disease database

(5) MalaCards diseases for MTA1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
tonsil cancer
  • malignant neoplasm of faucial tonsil
esophageal cancer
  • esophageal cancer, somatic
breast cancer
  • breast cancer, invasive ductal
colorectal cancer
  • colorectal cancer, somatic
microphthalmia, isolated 1
  • isolated microphthalmia 1
- elite association - COSMIC cancer census association via MalaCards
Search MTA1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for MTA1

Genetic Association Database (GAD)
MTA1
Human Genome Epidemiology (HuGE) Navigator
MTA1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MTA1
genes like me logo Genes that share disorders with MTA1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MTA1 Gene

Publications for MTA1 Gene

  1. Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines. (PMID: 7607577) Toh Y. … Nicolson G.L. (Gene 1995) 2 3 4 22 64
  2. A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. (PMID: 8083195) Toh Y. … Nicolson G.L. (J. Biol. Chem. 1994) 2 3 4 22 64
  3. MTA1 coregulator regulates p53 stability and function. (PMID: 19837670) Li D.Q. … Kumar R. (J. Biol. Chem. 2009) 3 4 22 64
  4. E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1. (PMID: 19805145) Li D.Q. … Kumar R. (Proc. Natl. Acad. Sci. U.S.A. 2009) 3 4 22 64
  5. MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene. (PMID: 17922032) Molli P.R. … Kumar R. (Oncogene 2008) 3 4 22 64

Products for MTA1 Gene

Sources for MTA1 Gene

Content
Loading form....