Aliases for SYT7 Gene
External Ids for SYT7 Gene
Previous HGNC Symbols for SYT7 Gene
Previous GeneCards Identifiers for SYT7 Gene
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for SYT7 Gene
SYT7 (Synaptotagmin VII) is a Protein Coding gene. Diseases associated with SYT7 include prostate cancer. GO annotations related to this gene include calcium ion binding and syntaxin binding. An important paralog of this gene is SYT5.
UniProtKB/Swiss-Prot for SYT7 Gene
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.