Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TRPA1 Gene

Aliases for TRPA1 Gene

  • Transient Receptor Potential Cation Channel Subfamily A Member 1 2 3 5
  • Ankyrin-Like With Transmembrane Domains 1 2 3
  • Transformation-Sensitive Protein P120 3 4
  • ANKTM1 3 4
  • Transient Receptor Potential Cation Channel, Subfamily A, Member 1 2
  • Ankyrin-Like With Transmembrane Domains Protein 1 4
  • FEPS1 3
  • FEPS 3

External Ids for TRPA1 Gene

Previous HGNC Symbols for TRPA1 Gene

  • ANKTM1

Previous GeneCards Identifiers for TRPA1 Gene

  • GC08M072983
  • GC08M073096
  • GC08M068428
  • GC08M072932

Summaries for TRPA1 Gene

Entrez Gene Summary for TRPA1 Gene

  • The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008]

GeneCards Summary for TRPA1 Gene

TRPA1 (Transient Receptor Potential Cation Channel Subfamily A Member 1) is a Protein Coding gene. Diseases associated with TRPA1 include Episodic Pain Syndrome, Familial, 1 and Somatoform Disorder. Among its related pathways are TRP channels and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include ion channel activity and channel activity. An important paralog of this gene is ANKFY1.

UniProtKB/Swiss-Prot for TRPA1 Gene

  • Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function (PubMed:25389312, PubMed:25855297). Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes (PubMed:25389312, PubMed:20547126). Is also activated by menthol (in vitro)(PubMed:25389312). Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312). May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).

Tocris Summary for TRPA1 Gene

  • The ankyrin-like receptor family (TRPA1) is a member of the transient receptor potential (TRP) superfamily of ion channels. TRPA1 is classed as a thermoTRP: a TRP channel which is gated by temperature and functions as a temperature transducer.

Gene Wiki entry for TRPA1 Gene

Additional gene information for TRPA1 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRPA1 Gene

Genomics for TRPA1 Gene

Regulatory Elements for TRPA1 Gene

Enhancers for TRPA1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H072106 1 ENCODE 0.4 -17.7 -17745 2 PKNOX1 FOXA2 ATF1 ARNT TCF12 ZNF766 ATF7 FOS SP3 NCOA1 GC08M071877 TRPA1
GH08H072075 0.8 ENCODE 0.4 +14.4 14379 0 HDAC1 KLF1 ZSCAN4 ZBTB40 ZIC2 GLIS2 CTBP1 POLR2A PRDM10 EZH2 MSC-AS1 TRPA1 RPS20P20
GH08H072095 0.7 FANTOM5 0.4 -6.1 -6090 0 HDAC1 TAL1 RELA TCF12 CTBP1 GATA2 NCOR1 SMARCE1 RFX1 SOX6 ENSG00000200191 TRPA1 GC08M071877
GH08H072004 1.1 Ensembl ENCODE 0.2 +84.8 84809 1 HDAC1 TBP ATF1 RB1 CBX5 EGR1 ZNF143 CREM SMARCA5 HCFC1 ENSG00000200191 MSC-AS1 TRPA1 RPS20P20
GH08H072014 0.8 ENCODE 0.2 +75.8 75839 0 PKNOX1 FOXA2 JUN MAX CEBPG FEZF1 RFX5 SMARCC2 RCOR1 FOS ENSG00000200191 TRPA1 RPS20P20
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRPA1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRPA1 Gene

Chromosome:
8
Start:
72,019,917 bp from pter
End:
72,090,009 bp from pter
Size:
70,093 bases
Orientation:
Minus strand

Genomic View for TRPA1 Gene

Genes around TRPA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRPA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRPA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPA1 Gene

Proteins for TRPA1 Gene

  • Protein details for TRPA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75762-TRPA1_HUMAN
    Recommended name:
    Transient receptor potential cation channel subfamily A member 1
    Protein Accession:
    O75762
    Secondary Accessions:
    • A6NIN6

    Protein attributes for TRPA1 Gene

    Size:
    1119 amino acids
    Molecular mass:
    127501 Da
    Quaternary structure:
    • Homotetramer (PubMed:25389312, PubMed:25855297). Interacts with TMEM100 (By similarity).

    Three dimensional structures from OCA and Proteopedia for TRPA1 Gene

neXtProt entry for TRPA1 Gene

Post-translational modifications for TRPA1 Gene

  • TRPA1 activation by electrophiles occurs though covalent modification of specific cysteine residues in the N-terminal cytoplasmic domain.
  • Glycosylation at Asn747 and posLast=753753
  • Modification sites at PhosphoSitePlus

Other Protein References for TRPA1 Gene

No data available for DME Specific Peptides for TRPA1 Gene

Domains & Families for TRPA1 Gene

Gene Families for TRPA1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Disease related genes
  • FDA approved drug targets
  • Predicted membrane proteins
  • Transporters
  • Voltage-gated ion channels

Protein Domains for TRPA1 Gene

Suggested Antigen Peptide Sequences for TRPA1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75762

UniProtKB/Swiss-Prot:

TRPA1_HUMAN :
  • C-terminal helices from the four subunits associate to form atypical coiled coil structure; this region is probably involved in binding the inositol polyphosphates that are required for optimal channel activity (in vitro).
  • Belongs to the transient receptor (TC 1.A.4) family.
Domain:
  • C-terminal helices from the four subunits associate to form atypical coiled coil structure; this region is probably involved in binding the inositol polyphosphates that are required for optimal channel activity (in vitro).
  • The ANK repeat domain consists of a convex stem structure formed by five ANK repeats and 11 additional ANK repeats that form a crescent-shaped structure that surrounds the protein core.
Family:
  • Belongs to the transient receptor (TC 1.A.4) family.
genes like me logo Genes that share domains with TRPA1: view

Function for TRPA1 Gene

Molecular function for TRPA1 Gene

UniProtKB/Swiss-Prot EnzymeRegulation:
Inhibited by ruthenium red, a potent blocker of TRPV channels.
UniProtKB/Swiss-Prot Function:
Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function (PubMed:25389312, PubMed:25855297). Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes (PubMed:25389312, PubMed:20547126). Is also activated by menthol (in vitro)(PubMed:25389312). Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312). May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).

Phenotypes From GWAS Catalog for TRPA1 Gene

Gene Ontology (GO) - Molecular Function for TRPA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005262 calcium channel activity IEA,TAS --
GO:0015267 channel activity IEA,TAS 10066796
GO:0015278 calcium-release channel activity IMP 25855297
GO:0097604 temperature-gated cation channel activity IDA 20547126
genes like me logo Genes that share ontologies with TRPA1: view
genes like me logo Genes that share phenotypes with TRPA1: view

Human Phenotype Ontology for TRPA1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for TRPA1 Gene

MGI Knock Outs for TRPA1:

Animal Model Products

  • Taconic Biosciences Mouse Models for TRPA1

CRISPR Products

miRNA for TRPA1 Gene

miRTarBase miRNAs that target TRPA1

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TRPA1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TRPA1 Gene

Localization for TRPA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRPA1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRPA1 gene
Compartment Confidence
plasma membrane 5
extracellular 2
peroxisome 1
cytosol 1

Gene Ontology (GO) - Cellular Components for TRPA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IMP,TAS 20547126
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0032421 stereocilium bundle IEA --
genes like me logo Genes that share ontologies with TRPA1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TRPA1 Gene

Pathways & Interactions for TRPA1 Gene

genes like me logo Genes that share pathways with TRPA1: view

Pathways by source for TRPA1 Gene

Gene Ontology (GO) - Biological Process for TRPA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0006811 ion transport TAS 10066796
GO:0006816 calcium ion transport IEA --
GO:0007166 cell surface receptor signaling pathway IEA --
GO:0009409 response to cold IEA --
genes like me logo Genes that share ontologies with TRPA1: view

No data available for SIGNOR curated interactions for TRPA1 Gene

Drugs & Compounds for TRPA1 Gene

(86) Drugs for TRPA1 Gene - From: DrugBank, ClinicalTrials, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Menthol Approved Pharma Partial agonist, Activator, activator, Target, inducer 2826
Apomorphine Approved, Investigational Pharma Partial agonist, Agonist, agonist 39
Auranofin Approved Pharma Activation, Activator, inhibitor Thioredoxin reductase inhibitor; induces MPT 11
Nicotine Approved Pharma Antagonist, antagonist 1148
Thymol Approved Pharma Activation, Activator 8

(8) Additional Compounds for TRPA1 Gene - From: IUPHAR, Novoseek, and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
1-acetoxychavicol acetate
Activation, Activator
2-pentenal
  • FEMA 3218
Agonist, Activator 764-39-6
chembridge-5861528
Inhibition, Gating inhibitor
cinnamaldehyde
  • (2E)-3-Phenyl-2-propenal
  • (2E)-3-phenylacrylaldehyde
  • (E)-3-Phenyl-2-propenal
  • (E)-3-Phenylpropenal
  • (E)-Cinnamaldehyde
Activation, Activator 104-55-2
Delta<sup>9</sup>-tetrahydrocannabinol
Partial agonist, Agonist

(5) Tocris Compounds for TRPA1 Gene

Compound Action Cas Number
A 967079 Selective TRPA1 channel blocker 1170613-55-4
ASP 7663 Selective TRPA1 activator 1190217-35-6
HC 030031 Selective TRPA1 blocker 349085-38-7
Icilin Activates a novel cold receptor. Cooling agent 36945-98-9
TCS 5861528 TRPA1 blocker 332117-28-9

(38) ApexBio Compounds for TRPA1 Gene

Compound Action Cas Number
5'-Iodoresiniferatoxin 535974-91-5
6'-Iodoresiniferatoxin 335151-55-8
9-Phenanthrol 484-17-3
A 967079 Selective TRPA1 channel blocker 1170613-55-4
AMTB hydrochloride 926023-82-7
AP 18 Reversible TRPA1 channel blocker 55224-94-7
BCTC 393514-24-4
EIPA 1154-25-2
GSK 2193874 1336960-13-4
GsMTx4
HC 067047 883031-03-6
HC-030031 TRPA1 channel blocker,potent and selective 349085-38-7
JNJ 17203212 821768-06-3
L-R4W2 206350-79-0
ML 204 5465-86-1
ML SA1 332382-54-4
Nonivamide 2444-46-4
OLDA 105955-11-1
Olvanil 58493-49-5
Ononetin 487-49-0
Optovin 348575-88-2
PALDA 136181-87-8
Phenamil 1161-94-0
Polygodial 6754-20-7
PPAHV 175796-50-6
Pyr3 1160514-60-2
Resiniferatoxin 57444-62-9
RN 1734 946387-07-1
RN 1747 1024448-59-6
SB 366791 472981-92-3
SB 452533 459429-39-1
SN 2 823218-99-1
STEARDA 105955-10-0
TC-I 2000 1159996-20-9
TCS 5861528 332117-28-9
TRPC6 inhibitor 1333207-63-8
WS 12 68489-09-8
α-Spinasterol 481-18-5
genes like me logo Genes that share compounds with TRPA1: view

Drug Products

Transcripts for TRPA1 Gene

mRNA/cDNA for TRPA1 Gene

Unigene Clusters for TRPA1 Gene

Transient receptor potential cation channel, subfamily A, member 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TRPA1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TRPA1 Gene

No ASD Table

Relevant External Links for TRPA1 Gene

GeneLoc Exon Structure for
TRPA1
ECgene alternative splicing isoforms for
TRPA1

Expression for TRPA1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRPA1 Gene

mRNA differential expression in normal tissues according to GTEx for TRPA1 Gene

This gene is overexpressed in Bladder (x15.7), Colon - Transverse (x8.8), Small Intestine - Terminal Ileum (x7.4), and Stomach (x5.3).

Protein differential expression in normal tissues from HIPED for TRPA1 Gene

This gene is overexpressed in Urine (50.9) and Platelet (17.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TRPA1 Gene



Protein tissue co-expression partners for TRPA1 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRPA1 Gene:

TRPA1

SOURCE GeneReport for Unigene cluster for TRPA1 Gene:

Hs.716816

mRNA Expression by UniProt/SwissProt for TRPA1 Gene:

O75762-TRPA1_HUMAN
Tissue specificity: Expressed at very low level. Expressed at very low level in human fibroblasts and at a moderate level in liposarcoma cells.

Evidence on tissue expression from TISSUES for TRPA1 Gene

  • Lung(4.4)
  • Nervous system(3)
  • Skin(2.7)
genes like me logo Genes that share expression patterns with TRPA1: view

Primer Products

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TRPA1 Gene

Orthologs for TRPA1 Gene

This gene was present in the common ancestor of animals.

Orthologs for TRPA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRPA1 33 34
  • 99.49 (n)
dog
(Canis familiaris)
Mammalia TRPA1 33 34
  • 85.94 (n)
cow
(Bos Taurus)
Mammalia TRPA1 33 34
  • 84.04 (n)
mouse
(Mus musculus)
Mammalia Trpa1 33 16 34
  • 81.06 (n)
rat
(Rattus norvegicus)
Mammalia Trpa1 33
  • 80.28 (n)
oppossum
(Monodelphis domestica)
Mammalia TRPA1 34
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TRPA1 34
  • 65 (a)
OneToOne
chicken
(Gallus gallus)
Aves TRPA1 33 34
  • 67.99 (n)
lizard
(Anolis carolinensis)
Reptilia TRPA1 34
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia trpa1 33
  • 60.98 (n)
zebrafish
(Danio rerio)
Actinopterygii trpa1a 33 34
  • 55.3 (n)
trpa1b 34
  • 46 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004863 33
  • 47.85 (n)
fruit fly
(Drosophila melanogaster)
Insecta TrpA1 33 34
  • 47.01 (n)
worm
(Caenorhabditis elegans)
Secernentea trpa-1 33 34
  • 43.78 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 22 (a)
OneToMany
-- 34
  • 21 (a)
OneToMany
Species where no ortholog for TRPA1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRPA1 Gene

ENSEMBL:
Gene Tree for TRPA1 (if available)
TreeFam:
Gene Tree for TRPA1 (if available)

Paralogs for TRPA1 Gene

Paralogs for TRPA1 Gene

(6) SIMAP similar genes for TRPA1 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for TRPA1 Gene

genes like me logo Genes that share paralogs with TRPA1: view

Variants for TRPA1 Gene

Sequence variations from dbSNP and Humsavar for TRPA1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs398123010 Pathogenic, Episodic pain syndrome, familial, 1 (FEPS1) [MIM:615040] 72,034,369(-) TGAAA(A/G)TTGTG intron-variant, reference, missense
rs1000004224 -- 72,071,579(+) ACCCA(C/G/T)AATTC intron-variant
rs1000025831 -- 72,030,857(+) ATTAG(C/G)TGGGG intron-variant
rs1000089152 -- 72,036,327(+) AGTAA(A/G)CAGCA intron-variant, reference, missense
rs1000109550 -- 72,035,263(+) CAGCA(A/C)GGCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRPA1 Gene

Variant ID Type Subtype PubMed ID
esv1942504 CNV deletion 18987734
esv2737154 CNV deletion 23290073
esv2737155 CNV deletion 23290073
esv2737156 CNV deletion 23290073
esv6851 CNV gain 19470904
nsv611530 CNV loss 21841781
nsv831353 CNV loss 17160897

Variation tolerance for TRPA1 Gene

Residual Variation Intolerance Score: 12.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.53; 91.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRPA1 Gene

Human Gene Mutation Database (HGMD)
TRPA1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRPA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRPA1 Gene

Disorders for TRPA1 Gene

MalaCards: The human disease database

(5) MalaCards diseases for TRPA1 Gene - From: HGMD, OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
episodic pain syndrome, familial, 1
  • familial episodic pain syndrome with predominantly upper body involvement
somatoform disorder
  • physiological malfunction arising from mental factor
dentin sensitivity
  • sensitive dentin
familial episodic pain syndrome
  • feps
pain disorder
  • paine syndrome
- elite association - COSMIC cancer census association via MalaCards
Search TRPA1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

TRPA1_HUMAN
  • Episodic pain syndrome, familial, 1 (FEPS1) [MIM:615040]: An autosomal dominant neurologic disorder characterized by onset in infancy of episodic debilitating upper body pain triggered by fasting, cold, and physical stress. The period of intense pain is accompanied by breathing difficulties, tachycardia, sweating, generalized pallor, peribuccal cyanosis, and stiffness of the abdominal wall. Affected individuals do not manifest altered pain sensitivity outside the episodes. {ECO:0000269 PubMed:20547126}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for TRPA1

Genetic Association Database (GAD)
TRPA1
Human Genome Epidemiology (HuGE) Navigator
TRPA1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRPA1
genes like me logo Genes that share disorders with TRPA1: view

No data available for Genatlas for TRPA1 Gene

Publications for TRPA1 Gene

  1. Structure of the TRPA1 ion channel suggests regulatory mechanisms. (PMID: 25855297) Paulsen CE … Julius D (Nature 2015) 3 4 60
  2. A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome. (PMID: 20547126) Kremeyer B … Ruiz-Linares A (Neuron 2010) 3 4 60
  3. Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells. (PMID: 19507192) Louhivuori LM … Akerman KE (Journal of cellular physiology 2009) 3 22 60
  4. QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells. (PMID: 19507004) Doihara H … Ito H (Molecular and cellular biochemistry 2009) 3 22 60
  5. Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. (PMID: 19074743) Bessac BF … Jordt SE (Physiology (Bethesda, Md.) 2008) 3 22 60

Products for TRPA1 Gene

Sources for TRPA1 Gene

Content
Loading form....